Reactome | PolyUb-CCNA1 [nucleoplasm]

PolyUb-CCNA1 [nucleoplasm]

Stable Identifier

R-HSA-6783068

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

CCNA1, Cyclin A1

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External Reference Information

External Reference

UniProt:P78396 CCNA1

Gene Names

CCNA1

Chain

chain:1-465

Reference Genes

BioGPS Gene:8900 CCNA1

COSMIC (genes):CCNA1 CCNA1

CTD Gene:8900 CCNA1

dbSNP Gene:8900 CCNA1

ENSEMBL:ENSG00000133101 CCNA1

HGNC:1577 CCNA1

KEGG:hsa:8900 CCNA1

Monarch:8900 CCNA1

NCBI Gene:8900 CCNA1

OMIM:604036 CCNA1

UCSC:P78396 CCNA1

Reference Transcript

Other Identifiers

11732350_a_at

16774053

1914_at

205899_PM_at

205899_at

3485675

3485676

3485677

3485678

3485679

3485680

3485681

3485682

3485683

3485684

3485686

3485687

3485688

3485689

3485691

3485692

7968637

8900

A_14_P104510

A_23_P48414

GE80093

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005813

GO:0005815

GO:0005829

GO:0005856

GO:0007141

GO:0007283

GO:0015630

GO:0016538

GO:0022414

GO:0043226

GO:0044772

GO:0051301

GO:0097121

GO:0097123

GO:0097124

GO:0098772

GO:0140013

HMNXSV003022709

ILMN_2157099

PH_hs_0019647

TC13000124.hg

U66838_at

g4502610_3p_at

Participates

as a member of

PolyUb-CCNA [nucleoplasm] (Homo sapiens)

Other forms of this molecule

CCNA1 [cytosol]

CCNA1 [nucleoplasm]

Inferred To

CCNA1 [nucleoplasm] (Bos taurus)

CCNA1 [nucleoplasm] (Canis familiaris)

CCNA1 [nucleoplasm] (Gallus gallus)

CCNA1 [nucleoplasm] (Sus scrofa)

ccna1 [nucleoplasm] (Danio rerio)

ccna1 [nucleoplasm] (Xenopus tropicalis)

Ccna1 [nucleoplasm] (Mus musculus)

Ccna1 [nucleoplasm] (Rattus norvegicus)

CycA [nucleoplasm] (Drosophila melanogaster)

crs1 [nucleoplasm] (Schizosaccharomyces pombe)

Homologues of PolyUb-CCNA1 [nucleoplasm] (Caenorhabditis elegans)

PolyUb-CCNA1 [nucleoplasm] (Caenorhabditis elegans)

cya-1 [nucleoplasm] (Caenorhabditis elegans)

Modified Residues

Name

ubiquitinylated lysine (PolyUb [nucleoplasm]) at unknown position

Modification

PolyUb [nucleoplasm]

PsiMod Name

ubiquitinylated lysine [MOD:01148]

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.

Cross References

RefSeq

NP_003905.1, XP_011533598.1, XP_011533597.1, NP_001104516.1, XP_011533596.1, NP_001104515.1, NP_001104517.1

ENSEMBL

ENST00000255465, ENSP00000486017, ENSP00000486482, ENST00000440264, ENST00000625767, ENSP00000400666, ENST00000630422, ENSP00000255465

OpenTargets

ENSG00000133101

HPA

ENSG00000133101-CCNA1

PRO

P78396

Pharos - Targets

P78396

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P38936 CDKN1A	5	p-S130-CDKN1A [nucleoplasm] (R-HSA-187857) CDKN1A [nucleoplasm] (R-HSA-182585) CDKN1A [cytosol] (R-HSA-182512) p-Y77-CDKN1A [cytosol] (R-HSA-8942601) p-T145-CDKN1A [cytosol] (R-HSA-198614)	0.838	8
UniProt:P46527 CDKN1B	8	p-T187-CDKN1B [nucleoplasm] (R-HSA-187525) CDKN1B [nucleoplasm] (R-HSA-182563) p-Y88-CDKN1B [nucleoplasm] (R-HSA-8942808) p-Y88-CDKN1B [cytosol] (R-HSA-8848438) CDKN1B [cytosol] (R-HSA-198622) p-T157-CDKN1B [cytosol] (R-HSA-198629) p-S10 CDKN1B [nucleoplasm] (R-HSA-9632832) p-S10 CDKN1B [cytosol] (R-HSA-9632829)	0.783	7
UniProt:Q05397 PTK2	11	p-6Y-PTK2 [cytosol] (R-HSA-354128) p-Y397-PTK2 [cytosol] (R-HSA-354068) PTK2 [cytosol] (R-HSA-201621) PTK2(1-772) [cytosol] (R-HSA-202827) PTK2(773-1052) [cytosol] (R-HSA-202829) p-5Y-PTK2 [cytosol] (R-HSA-5218711) p-5Y,S732-PTK2 [cytosol] (R-HSA-5229006) p-6Y,S732-PTK2 [cytosol] (R-HSA-5218694) pY-PTK2 [cytosol] (R-HSA-9632393) p-Y194,Y397-PTK2 [cytosol] (R-HSA-8874600) p-Y194,Y397,Y576,Y577-PTK2 [cytosol] (R-HSA-8874613)	0.536	2

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