Spontaneous hydrolysis of 1-pyrroline-3-hydroxy-5-carboxylate to 4-OH-L-glutamate semialdehyde

Stable Identifier
R-HSA-6784402
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
1-pyrroline-3-hydroxy-5-carboxylate + H2O => 4-OH-L-glutamate semialdehyde
ReviewStatus
5/5
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Spontaneous hydrolysis of 1-pyrroline-3-hydroxy-5-carboxylate to 4-OH-L-glutamate semialdehyde
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The spontaneous hydrolysis of 1-pyrroline-3-hydroxy-5-carboxylate to form 4-OH-L-glutamate semialdehyde is inferred from the behavior of the analogous intermediate of proline catabolism (Moxley et al. 2011).
Literature References
PubMed ID Title Journal Year
22040654 Steady-state kinetic mechanism of the proline:ubiquinone oxidoreductase activity of proline utilization A (PutA) from Escherichia coli

Tanner, JJ, Becker, DF, Moxley, MA

Arch. Biochem. Biophys. 2011
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Event Information
Go Biological Process
glyoxylate metabolic process (0046487)
Authored
D'Eustachio, P  (2015-06-19)
Reviewed
Jassal, B  (2016-12-23)
Created
D'Eustachio, P  (2015-06-19)
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