Reactome | p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus

p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus

Stable Identifier

R-HSA-6786293

Type

Reaction [BlackBoxEvent]

Species

Homo sapiens

Compartment

cytosol, nucleoplasm

Synonyms

Phosphorylated STAT3 and STAT6 dimers translocate to the nucleus

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p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus

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Phosphorylated, dimerized Signal transducer and activator of transcription 6 (STAT6) translocates to the nucleus where it regulates the expression of multiple genes (Mikita et al. 1996, Daines et al. 2003, Hebenstreit et al. 2006, Goenka & Kaplan 2011).

Literature References

PubMed ID	Title	Journal	Year
8816495	Requirements for interleukin-4-induced gene expression and functional characterization of Stat6 Schindler, U, Campbell, D, Mikita, T, Williamson, K, Wu, P	Mol. Cell. Biol.	1996