Reactome | WTAP [nucleoplasm]

WTAP [nucleoplasm]

Stable Identifier

R-HSA-6789461

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Pre-mRNA-splicing regulator WTAP, FL2D_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q15007 WTAP

Gene Names

WTAP, KIAA0105

Chain

chain:1-396

Reference Genes

BioGPS Gene:9589 WTAP

COSMIC (genes):WTAP WTAP

CTD Gene:9589 WTAP

dbSNP Gene:9589 WTAP

ENSEMBL:ENSG00000146457 WTAP

HGNC:16846 WTAP

KEGG:hsa:9589 WTAP

Monarch:9589 WTAP

NCBI Gene:9589 WTAP

OMIM:605442 WTAP

UCSC:Q15007 WTAP

Reference Transcript

Participates

as a component of

mRNA (N6-adenosine)-methyltransferase [nucleoplasm] (Homo sapiens)

Inferred To

fl(2)d [nucleoplasm] (Drosophila melanogaster)

Wtap [nucleoplasm] (Mus musculus)

Wtap [nucleoplasm] (Rattus norvegicus)

wtap [nucleoplasm] (Danio rerio)

wtap [nucleoplasm] (Xenopus tropicalis)

WTAP [nucleoplasm] (Bos taurus)

WTAP [nucleoplasm] (Plasmodium falciparum)

WTAP [nucleoplasm] (Sus scrofa)

Cross References

RefSeq

XP_047275534.1, NP_004897.2, XP_054212834.1, NP_001257461.1, NP_690596.1, NP_001257460.1, NP_690597.1, NP_001257462.1

OpenTargets

ENSG00000146457

ENSEMBL

ENST00000358372, ENST00000337387, ENST00000650096, ENSP00000351141, ENST00000621533, ENSP00000497840, ENSG00000146457, ENSP00000479438, ENSP00000336911

HPA

ENSG00000146457-WTAP

GeneCards

WTAP

PRO

Q15007

Pharos - Targets

Q15007

GlyGen

Q15007

PDB

7VF5, 7YG4, 7VF2, 7YFJ

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P63104 YWHAZ	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.564	2
UniProt:Q13895 BYSL	2	BYSL [nucleoplasm] (R-HSA-6791526) BYSL [cytosol] (R-HSA-6791518)	0.556	3
UniProt:P25786 PSMA1	2	PSMA1 [cytosol] (R-HSA-68724) PSMA1 [nucleoplasm] (R-HSA-174333)	0.556	3
UniProt:Q6UWZ7 ABRAXAS1	1	p-S406-FAM175A [nucleoplasm] (R-HSA-5682575)	0.527	2

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