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ZEB1 [nucleoplasm]
Stable Identifier
R-HSA-6789836
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Zinc finger E-box-binding homeobox 1, ZEB1_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
MITF-M-regulated melanocyte development (Homo sapiens)
MITF-M-dependent gene expression (Homo sapiens)
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition (Homo sapiens)
MITF-M-dependent ZEB1 gene expression (Homo sapiens)
ZEB1 [nucleoplasm] (Homo sapiens)
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-4 and Interleukin-13 signaling (Homo sapiens)
Expression of STAT3-upregulated nuclear proteins (Homo sapiens)
STAT3-upregulated nuclear proteins [nucleoplasm] (Homo sapiens)
ZEB1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P37275 ZEB1
Gene Names
ZEB1, AREB6, TCF8
Chain
chain:1-1124
Reference Genes
BioGPS Gene:6935 ZEB1
COSMIC (genes):ZEB1 ZEB1
CTD Gene:6935 ZEB1
dbSNP Gene:6935 ZEB1
ENSEMBL:ENSG00000148516 ZEB1
HGNC:11642 ZEB1
KEGG:hsa:6935 ZEB1
Monarch:6935 ZEB1
NCBI Gene:6935 ZEB1
OMIM:189909 ZEB1
UCSC:P37275 ZEB1
Reference Transcript
RefSeq:NM_001174096.1 ZEB1
RefSeq:NM_001128128.2 ZEB1
RefSeq:NM_001174093.1 ZEB1
RefSeq:NM_001174094.1 ZEB1
RefSeq:NM_001174095.1 ZEB1
RefSeq:NM_030751.5 ZEB1
Other Identifiers
11721545_x_at
11721546_s_at
11721547_s_at
11734686_x_at
11749136_x_at
11749644_s_at
11758473_s_at
16703715
210875_PM_s_at
210875_s_at
212758_PM_s_at
212758_s_at
212764_PM_at
212764_at
239952_PM_at
239952_at
3241317
3241318
3241319
3241320
3241321
3241330
3241331
3241340
3241342
3241343
3241344
3241345
3241360
3241361
3241368
3241369
3241370
3241371
3241374
3241378
3241379
3241381
3241382
3241383
3241384
3241385
3241386
3241387
3241388
3241389
33440_at
57311_at
61486_at
6935
74451_at
7926916
A_14_P102704
A_14_P111969
A_14_P114639
A_14_P129718
A_19_P00331133
A_23_P202013
A_33_P3374723
A_33_P3640690
GE563654
GO:0000122
GO:0000785
GO:0000978
GO:0000981
GO:0001227
GO:0003677
GO:0003682
GO:0003690
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005829
GO:0006355
GO:0006357
GO:0007389
GO:0007399
GO:0007417
GO:0008270
GO:0008283
GO:0010464
GO:0010839
GO:0014823
GO:0017015
GO:0030154
GO:0030857
GO:0030900
GO:0031667
GO:0033081
GO:0043226
GO:0043565
GO:0043616
GO:0045602
GO:0045666
GO:0045892
GO:0045944
GO:0046872
GO:0048513
GO:0048596
GO:0048598
GO:0048704
GO:0048752
GO:0048856
GO:0050673
GO:0050680
GO:0051150
GO:0051216
GO:0070888
GO:0071230
GO:0071560
GO:0090103
GO:0140110
HMNXSV003030533
HMNXSV003039633
Hs.104372.0.A1_3p_at
Hs.232068.2.A1_3p_s_at
Hs.232068.2.A2_3p_at
ILMN_1762231
PH_hs_0012717
TC10000219.hg
g529172_3p_a_at
p24856
Participates
as a member of
STAT3-upregulated nuclear proteins [nucleoplasm] (Homo sapiens)
as an output of
MITF-M-dependent ZEB1 gene expression (Homo sapiens)
Cross References
ENSEMBL
ENST00000320985
,
ENSP00000415961
,
ENST00000560721
,
ENST00000446923
,
ENST00000542815
,
ENSP00000319248
,
ENSG00000148516
,
ENSP00000391612
,
ENSP00000452787
,
ENST00000424869
,
ENSP00000444891
OpenTargets
ENSG00000148516
GeneCards
ZEB1
HPA
ENSG00000148516-ZEB1
PRO
P37275
Pharos - Targets
P37275
GlyGen
P37275
Orphanet
ZEB1
HMDB Protein
HMDBP10917
PDB
2E19
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13363 CTBP1
3
CTBP1 [nucleoplasm]
(R-HSA-212372)
polySUMO2,3-K428-CTBP1 [nucleoplasm]
(R-HSA-3108226)
monoSUMO1-K428-CTBP1 [nucleoplasm]
(R-HSA-3108200)
0.859
12
UniProt:Q92769 HDAC2
2
HDAC2 [nucleoplasm]
(R-HSA-205135)
monoSUMO1-K462-HDAC2 [nucleoplasm]
(R-HSA-4615958)
0.527
2
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