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UTP14A [nucleoplasm]
Stable Identifier
R-HSA-6790695
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
U3 small nucleolar RNA-associated protein 14 homolog A, UT14A_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
rRNA processing (Homo sapiens)
rRNA processing in the nucleus and cytosol (Homo sapiens)
Major pathway of rRNA processing in the nucleolus and cytosol (Homo sapiens)
21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA (Homo sapiens)
18SE pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
UTP14A,C [nucleoplasm] (Homo sapiens)
UTP14A [nucleoplasm] (Homo sapiens)
21S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
UTP14A,C [nucleoplasm] (Homo sapiens)
UTP14A [nucleoplasm] (Homo sapiens)
30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA (Homo sapiens)
21S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
UTP14A,C [nucleoplasm] (Homo sapiens)
UTP14A [nucleoplasm] (Homo sapiens)
30S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
UTP14A,C [nucleoplasm] (Homo sapiens)
UTP14A [nucleoplasm] (Homo sapiens)
45S pre-rRNA is nucleolytically processed at site 2 (site 2b) to yield 30S pre-rRNA and 32S pre-rRNA (Homo sapiens)
30S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
UTP14A,C [nucleoplasm] (Homo sapiens)
UTP14A [nucleoplasm] (Homo sapiens)
45S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
UTP14A,C [nucleoplasm] (Homo sapiens)
UTP14A [nucleoplasm] (Homo sapiens)
47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA (Homo sapiens)
45S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
UTP14A,C [nucleoplasm] (Homo sapiens)
UTP14A [nucleoplasm] (Homo sapiens)
47S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
UTP14A,C [nucleoplasm] (Homo sapiens)
UTP14A [nucleoplasm] (Homo sapiens)
rRNA modification in the nucleus and cytosol (Homo sapiens)
EMG1 of the SSU processome methylates pseudouridine-1248 of 18S rRNA yielding N(1)-methylpseudouridine-1248 (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
UTP14A,C [nucleoplasm] (Homo sapiens)
UTP14A [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9BVJ6 UTP14A
Gene Names
UTP14A, SDCCAG16
Chain
chain:1-771
Reference Genes
BioGPS Gene:10813 UTP14A
COSMIC (genes):UTP14A UTP14A
CTD Gene:10813 UTP14A
dbSNP Gene:10813 UTP14A
ENSEMBL:ENSG00000156697 UTP14A
HGNC:10665 UTP14A
Monarch:10813 UTP14A
NCBI Gene:10813 UTP14A
OMIM:300508 UTP14A
UCSC:Q9BVJ6 UTP14A
Reference Transcript
RefSeq:NM_006649.3 UTP14A
RefSeq:NM_001166221.1 UTP14A
Other Identifiers
10813
11733838_s_at
17106895
221098_3p_x_at
221098_x_at
221513_PM_s_at
221513_s_at
221514_PM_at
221514_at
3490539
3990574
3990575
3990577
3990578
3990580
3990583
3990584
3990586
3990587
3990588
3990589
3990590
3990591
3990592
3990593
3990594
3990595
3990596
3990597
3990598
3990601
3990602
3990603
59733_s_at
74734_at
8169868
A_14_P104928
A_23_P205216
A_24_P170538
GE543941
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0005730
GO:0005829
GO:0006364
GO:0032040
GO:0042254
GO:0043226
HMNXSV003036335
HMNXSV003057378
ILMN_1688725
ILMN_2095820
PH_hs_0032403
TC0X000619.hg
g12654624_3p_at
g12654624_3p_x_at
Participates
as a member of
UTP14A,C [nucleoplasm] (Homo sapiens)
Inferred To
Utp14a [nucleoplasm]
(Mus musculus)
Utp14a [nucleoplasm]
(Rattus norvegicus)
Dmel\CG12301 [nucleoplasm]
(Drosophila melanogaster)
utp14 [nucleoplasm]
(Dictyostelium discoideum)
UTP14A [nucleoplasm]
(Bos taurus)
UTP14A [nucleoplasm]
(Caenorhabditis elegans)
UTP14A [nucleoplasm]
(Canis familiaris)
UTP14A [nucleoplasm]
(Gallus gallus)
UTP14A [nucleoplasm]
(Plasmodium falciparum)
UTP14A [nucleoplasm]
(Saccharomyces cerevisiae)
UTP14A [nucleoplasm]
(Schizosaccharomyces pombe)
UTP14A [nucleoplasm]
(Sus scrofa)
Cross References
ENSEMBL
ENST00000425117
,
ENSP00000377944
,
ENST00000394422
,
ENSP00000388669
OpenTargets
ENSG00000156697
HPA
ENSG00000156697-UTP14A
PRO
Q9BVJ6
Pharos - Targets
Q9BVJ6
GlyGen
Q9BVJ6
PDB
7MQ9
,
7MQ8
,
7WTS
,
7MQA
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.666
4
UniProt:Q8NB12 SMYD1
1
SMYD1 [nucleoplasm]
(R-HSA-5688412)
0.666
4
UniProt:P05067 APP
20
APP(672-713) [extracellular region]
(R-HSA-879340)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
0.556
3
UniProt:P63000 RAC1
6
RAC1 [plasma membrane]
(R-HSA-351141)
RAC1 [cytosol]
(R-HSA-442615)
GGC-PalmC-RAC1 [plasma membrane]
(R-HSA-2316446)
RAC1 [ficolin-1-rich granule membrane]
(R-HSA-6804802)
RAC1 [secretory granule membrane]
(R-HSA-6804770)
RAC1 [endoplasmic reticulum membrane]
(R-HSA-5672076)
0.556
3
UniProt:P0DTC9 N
13
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729340)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9729341)
ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729275)
p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729308)
p-11S,2T-N [cytosol]
(R-COV-9729264)
p-8S,2T-N [cytosol]
(R-COV-9729277)
p-8S-N [cytosol]
(R-COV-9729335)
p-S188,206-N [cytosol]
(R-COV-9729324)
N [cytosol]
(R-COV-9694300)
SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol]
(R-COV-9756489)
N [plasma membrane]
(R-COV-9694356)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus]
(R-COV-9729339)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane]
(R-COV-9729325)
0.527
2
UniProt:P03372 ESR1
10
ESR1 [cytosol]
(R-HSA-9020968)
ESR1 [nucleoplasm]
(R-HSA-446168)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
p-S167-ESR1 [cytosol]
(R-HSA-9841254)
p-S167-ESR1 [nucleoplasm]
(R-HSA-9841867)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
0.527
3
UniProt:P06748 NPM1
11
NPM1 [cytosol]
(R-HSA-3008211)
p-S4-NPM1 [cytosol]
(R-HSA-6801679)
NPM1 [nucleoplasm]
(R-HSA-606320)
NPM1 [granular component]
(R-HSA-9017702)
NPM1(1-117)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9699834)
NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9699861)
NPM1(1-117)-ALK(1068-1620) fusion [cytosol]
(R-HSA-9730697)
NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol]
(R-HSA-9730703)
NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm]
(R-HSA-9725010)
polySUMO2,3-K263-NPM1 [nucleoplasm]
(R-HSA-4086056)
monoSUMO1-K263-NPM1 [nucleoplasm]
(R-HSA-4086039)
0.483
2
UniProt:P62280 RPS11
2
RPS11 [cytosol]
(R-HSA-72327)
RPS11 [nucleoplasm]
(R-HSA-6791212)
0.483
2
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