Reactome | WDR3 [nucleoplasm]

WDR3 [nucleoplasm]

Stable Identifier

R-HSA-6790724

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

WD repeat-containing protein 3, WDR3_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9UNX4 WDR3

Gene Names

WDR3

Chain

chain:1-943

Reference Genes

BioGPS Gene:10885 WDR3

COSMIC (genes):WDR3 WDR3

CTD Gene:10885 WDR3

dbSNP Gene:10885 WDR3

ENSEMBL:ENSG00000065183 WDR3

HGNC:12755 WDR3

Monarch:10885 WDR3

NCBI Gene:10885 WDR3

OMIM:604737 WDR3

UCSC:Q9UNX4 WDR3

Reference Transcript

RefSeq:NM_006784.2 WDR3

Other Identifiers

10885

11742734_s_at

11751592_a_at

1557593_PM_at

1557593_at

16669288

218882_PM_s_at

218882_s_at

2354081

2354083

2354084

2354088

2354089

2354090

2354091

2354092

2354093

2354094

2354095

2354096

2354097

2354098

2354100

2354101

2354102

2354103

2354104

2354106

2354108

2354109

2354110

2354111

2354112

2354113

2354114

2354115

2354116

2354118

2354119

2354120

2354121

2354123

2354124

2354126

2354127

2354128

2354129

2354130

2354131

2354133

2354134

2354135

2354137

2354139

2354141

64096_at

7904364

80919_at

A_14_P201561

A_23_P23318

A_24_P122524

A_33_P3211633

GE58423

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005730

GO:0030490

GO:0030515

GO:0031965

GO:0032040

GO:0034388

GO:0042254

GO:0042274

GO:0043226

HMNXSV003020407

Hs2.87771.1.S1_3p_at

Hs2.87771.1.S1_3p_s_at

ILMN_1711254

PH_hs_0022987

TC01001033.hg

TC01004662.hg

g5803220_3p_a_at

p28225

Participates

as a component of

UTPB complex [nucleoplasm] (Homo sapiens)

Inferred To

WDR3 [nucleoplasm] (Bos taurus)

WDR3 [nucleoplasm] (Caenorhabditis elegans)

WDR3 [nucleoplasm] (Canis familiaris)

WDR3 [nucleoplasm] (Gallus gallus)

WDR3 [nucleoplasm] (Plasmodium falciparum)

WDR3 [nucleoplasm] (Schizosaccharomyces pombe)

WDR3 [nucleoplasm] (Sus scrofa)

Dmel\CG8064 [nucleoplasm] (Drosophila melanogaster)

wdr3 [nucleoplasm] (Dictyostelium discoideum)

DIP2 [nucleoplasm] (Saccharomyces cerevisiae)

Wdr3 [nucleoplasm] (Mus musculus)

Wdr3 [nucleoplasm] (Rattus norvegicus)

Cross References

ENSEMBL

ENSP00000308179, ENST00000349139

OpenTargets

ENSG00000065183

HPA

ENSG00000065183-WDR3

PRO

Q9UNX4

Pharos - Targets

Q9UNX4

GlyGen

Q9UNX4

PDB

7MQ8, 7MQ9, 7MQA

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O43159 RRP8	1	RRP8 [nucleoplasm] (R-HSA-427524)	0.527	3
UniProt:P0DTC9 N	13	SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729340) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9729341) ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729275) p-11S,2T-metR95,177-N [cytosol] (R-COV-9729308) p-11S,2T-N [cytosol] (R-COV-9729264) p-8S,2T-N [cytosol] (R-COV-9729277) p-8S-N [cytosol] (R-COV-9729335) p-S188,206-N [cytosol] (R-COV-9729324) N [cytosol] (R-COV-9694300) SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol] (R-COV-9756489) N [plasma membrane] (R-COV-9694356) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus] (R-COV-9729339) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane] (R-COV-9729325)	0.527	2
UniProt:P06748 NPM1	11	NPM1 [cytosol] (R-HSA-3008211) p-S4-NPM1 [cytosol] (R-HSA-6801679) NPM1 [nucleoplasm] (R-HSA-606320) NPM1 [granular component] (R-HSA-9017702) NPM1(1-117)-ALK(1058-1620) fusion [cytosol] (R-HSA-9699834) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9699861) NPM1(1-117)-ALK(1068-1620) fusion [cytosol] (R-HSA-9730697) NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol] (R-HSA-9730703) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm] (R-HSA-9725010) polySUMO2,3-K263-NPM1 [nucleoplasm] (R-HSA-4086056) monoSUMO1-K263-NPM1 [nucleoplasm] (R-HSA-4086039)	0.527	2