Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
RPS3A [nucleoplasm]
Stable Identifier
R-HSA-6791182
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
fullName evidence="2"40S ribosomal protein S3a, RS3A_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
rRNA processing (Homo sapiens)
rRNA processing in the nucleus and cytosol (Homo sapiens)
Major pathway of rRNA processing in the nucleolus and cytosol (Homo sapiens)
18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol (Homo sapiens)
18SE pre-40S particle [nucleoplasm] (Homo sapiens)
RPS3A [nucleoplasm] (Homo sapiens)
30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA (Homo sapiens)
RPS3A [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P61247 RPS3A
Gene Names
RPS3A, FTE1, MFTL
Chain
initiator methionine:1, chain:2-264
Reference Genes
BioGPS Gene:6189 RPS3A
COSMIC (genes):RPS3A RPS3A
CTD Gene:6189 RPS3A
dbSNP Gene:6189 RPS3A
ENSEMBL:ENSG00000145425 RPS3A
ENSEMBL:ENSG00000145425.10 RPS3A
HGNC:10421 RPS3A
KEGG Gene (Homo sapiens):6189 RPS3A
Monarch:6189 RPS3A
NCBI Gene:6189 RPS3A
OMIM:180478 RPS3A
UCSC:P61247 RPS3A
Reference Transcript
RefSeq:NM_001006.4 RPS3A
Other Identifiers
11716320_x_at
1653_at
16971413
18670014
18670019
18670020
18670021
18670022
18670023
18670025
18670027
18670028
18670029
18670030
200099_PM_s_at
200099_s_at
201257_PM_x_at
201257_x_at
212391_PM_x_at
212391_x_at
2612273
2640149
2683221
2747386
2747387
2747392
2747394
2747396
2747397
2747404
2747406
2864032
2870769
2870772
3061872
3062954
3062956
3062958
3062959
3062962
3062963
3084158
3084759
3122846
3124697
3124911
3255508
3255510
3255512
3259229
3359842
3379154
3482604
3596234
3596235
3596236
3621007
3621014
3790794
3790796
3957133
6189
7894205
7894971
7894982
7988031
8097782
8103222
8141050
8141222
A_23_P144497
GO:0002181
GO:0003723
GO:0003735
GO:0005198
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0005783
GO:0005829
GO:0005840
GO:0005925
GO:0006412
GO:0006413
GO:0012501
GO:0022626
GO:0022627
GO:0030154
GO:0032040
GO:0042254
GO:0042274
GO:0043066
GO:0043226
GO:0045202
GO:0048027
GO:0070062
GO:1990904
HMNXSV003004860
HMNXSV003018368
Hs.77039.1.S1_3p_x_at
ILMN_1657722
ILMN_1673638
ILMN_2139943
M84711_at
PH_hs_0029871
g4506722_3p_x_at
Participates
as a component of
18SE pre-40S particle [nucleoplasm] (Homo sapiens)
This entity regulates
Positively
30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA
(Homo sapiens)
Other forms of this molecule
RPS3A [cytosol]
Inferred To
RPS3A [nucleoplasm]
(Bos taurus)
RPS3A [nucleoplasm]
(Canis familiaris)
RPS3A [nucleoplasm]
(Gallus gallus)
RPS3A [nucleoplasm]
(Plasmodium falciparum)
RPS3A [nucleoplasm]
(Sus scrofa)
RpS3A [nucleoplasm]
(Drosophila melanogaster)
RPS1B [nucleoplasm]
(Saccharomyces cerevisiae)
rps-1 [nucleoplasm]
(Caenorhabditis elegans)
rps101 [nucleoplasm]
(Schizosaccharomyces pombe)
Rps3a [nucleoplasm]
(Mus musculus)
Rps3a [nucleoplasm]
(Rattus norvegicus)
rps3a [nucleoplasm]
(Danio rerio)
rps3a [nucleoplasm]
(Dictyostelium discoideum)
rps3a [nucleoplasm]
(Xenopus tropicalis)
Cross References
RefSeq
NP_000997.1
OpenTargets
ENSG00000145425
HPA
ENSG00000145425-RPS3A
GeneCards
P61247
Ensembl
ENST00000274065
,
ENSP00000346050
,
ENSG00000145425
PRO
P61247
Pharos - Targets
P61247
PDB
6ZVJ
,
6IP6
,
7WTZ
,
6ZXD
,
6Y0G
,
6Z6L
,
7WTS
,
6ZMW
,
6Y57
,
6ZLW
,
7A09
,
6ZN5
,
6OM7
,
6OM0
,
6QZP
,
6ZXF
,
7K5I
,
5A2Q
,
6OLE
,
7TQL
,
7WTU
,
4UG0
,
6Z6N
,
7WU0
,
7QVP
,
6OLI
,
6OLF
,
5VYC
,
6ZV6
,
6OLG
,
7R4X
,
7MQ9
,
6Y2L
,
6ZMO
,
6ZXE
,
6IP5
,
6G5H
,
6IP8
,
7MQA
,
6ZVH
,
4V6X
,
6ZOK
,
6FEC
,
6ZMT
,
5FLX
,
6OLZ
,
6ZOJ
,
6YBW
,
6G5I
,
6ZP4
,
6ZXH
,
7WTV
,
6G18
,
5OA3
,
7QP7
,
6G51
,
5AJ0
,
6Z6M
,
6ZM7
,
7MQ8
,
6ZUO
,
7QP6
,
7WTT
,
6ZXG
,
6G4S
,
6ZON
,
5LKS
,
7WTX
,
6ZMI
,
6YBD
,
6G4W
,
5T2C
,
7WTW
,
6ZME
,
6G53
,
6XA1
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P07900 HSP90AA1
8
HSP90AA1 [endocytic vesicle lumen]
(R-HSA-3221912)
HSP90AA1 [secretory granule lumen]
(R-HSA-6801515)
HSP90AA1 [extracellular region]
(R-HSA-3221946)
HSP90AA1 [ficolin-1-rich granule lumen]
(R-HSA-6801470)
HSP90AA1 [plasma membrane]
(R-HSA-534996)
HSP90AA1 [nucleoplasm]
(R-HSA-5082401)
HSP90AA1 [cytosol]
(R-HSA-192864)
HSP90AA1 [lysosomal lumen]
(R-HSA-9622850)
0.635
3
UniProt:P62263 RPS14
2
RPS14 [nucleoplasm]
(R-HSA-6790669)
RPS14 [cytosol]
(R-HSA-72333)
0.564
2
UniProt:P0DTC9 N
13
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane]
(R-COV-9729325)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus]
(R-COV-9729339)
N [plasma membrane]
(R-COV-9694356)
SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol]
(R-COV-9756489)
N [cytosol]
(R-COV-9694300)
p-S188,206-N [cytosol]
(R-COV-9729324)
p-8S-N [cytosol]
(R-COV-9729335)
p-8S,2T-N [cytosol]
(R-COV-9729277)
p-11S,2T-N [cytosol]
(R-COV-9729264)
p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729308)
ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729275)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9729341)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729340)
0.527
4
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.527
3
UniProt:P63244 RACK1
1
GNB2L1 [cytosol]
(R-HSA-5626956)
0.495
2
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.483
12
UniProt:P03372 ESR1
8
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
ESR1 [nucleoplasm]
(R-HSA-446168)
ESR1 [cytosol]
(R-HSA-9020968)
0.462
2
© 2023
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text