Reactome | RPS24 [nucleoplasm]

RPS24 [nucleoplasm]

Stable Identifier

R-HSA-6791186

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

40S ribosomal protein S24, RS24_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P62847 RPS24

Gene Names

RPS24

Chain

chain:1-133

Reference Genes

BioGPS Gene:6229 RPS24

COSMIC (genes):RPS24 RPS24

CTD Gene:6229 RPS24

dbSNP Gene:6229 RPS24

ENSEMBL:ENSG00000138326 RPS24

ENSEMBL:ENSG00000138326.21 RPS24

HGNC:10411 RPS24

KEGG Gene (Homo sapiens):6229 RPS24

Monarch:6229 RPS24

NCBI Gene:6229 RPS24

OMIM:602412 RPS24

UCSC:P62847 RPS24

Reference Transcript

Other Identifiers

11740590_at

11757021_x_at

18670719

18670722

18670723

18670725

18670729

18670731

18670732

200061_PM_s_at

200061_s_at

32315_at

3253439

3253443

3253444

3253445

3253447

3253453

3253457

3253463

3253464

6229

64287_s_at

7894061

7894214

7895026

7895622

7895687

7928551

A_19_P00804723

A_23_P1206

GE711672

GO:0002181

GO:0002376

GO:0003723

GO:0003735

GO:0005198

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0005783

GO:0005829

GO:0005840

GO:0006364

GO:0006412

GO:0015935

GO:0016020

GO:0022626

GO:0022627

GO:0031369

GO:0032040

GO:0034101

GO:0042254

GO:0042274

GO:0043226

GO:0110165

GO:1990904

HMNXSV003022039

HMNXSV003046110

ILMN_1656625

ILMN_2399893

M31520_at

g12653502_3p_s_at

Participates

as a component of

18SE pre-40S particle [nucleoplasm] (Homo sapiens)

This entity regulates

Positively

30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA (Homo sapiens)

Other forms of this molecule

RPS24 [cytosol]

Inferred To

rps2402 [nucleoplasm] (Schizosaccharomyces pombe)

Homologues of RPS24 [nucleoplasm] (Saccharomyces cerevisiae)

Homologues of RPS24 [nucleoplasm] (Schizosaccharomyces pombe)

Rps24 [nucleoplasm] (Mus musculus)

Rps24 [nucleoplasm] (Rattus norvegicus)

RPS24A [nucleoplasm] (Saccharomyces cerevisiae)

Ghost homologue of RPS24 [nucleoplasm] (Xenopus tropicalis)

RpS24 [nucleoplasm] (Drosophila melanogaster)

rps-24 [nucleoplasm] (Caenorhabditis elegans)

RPS24B [nucleoplasm] (Saccharomyces cerevisiae)

rps2401 [nucleoplasm] (Schizosaccharomyces pombe)

RPS24 [nucleoplasm] (Bos taurus)

RPS24 [nucleoplasm] (Canis familiaris)

RPS24 [nucleoplasm] (Gallus gallus)

RPS24 [nucleoplasm] (Plasmodium falciparum)

RPS24 [nucleoplasm] (Sus scrofa)

wu:fa66b02 [nucleoplasm] (Danio rerio)

rps24 [nucleoplasm] (Dictyostelium discoideum)

Cross References

RefSeq

NP_001135757.1, NP_001135755.1, NP_148982.1, NP_001017.1

OpenTargets

ENSG00000138326

HPA

ENSG00000138326-RPS24

GeneCards

P62847

Ensembl

ENSP00000494231, ENST00000613865, ENST00000440692, ENSP00000414321, ENSP00000361435, ENSG00000138326, ENSP00000478869, ENST00000372360, ENST00000464716

PRO

P62847

Pharos - Targets

P62847

Orphanet

15230

PDB

6ZXE, 7WTW, 6Y57, 6IP5, 6OLE, 5A2Q, 7QP6, 6ZMO, 6OLZ, 5FLX, 4V6X, 7WTZ, 6MTE, 6G51, 6ZP4, 6G4W, 6ZUO, 6ZME, 6G18, 7WTS, 6ZON, 6OLI, 6G4S, 6ZM7, 6ZOK, 4UG0, 6OLF, 6ZLW, 6ZXF, 6ZMT, 7WTV, 6ZOJ, 6ZVH, 6Z6L, 5AJ0, 7R4X, 6FEC, 6ZXD, 6G5H, 6OM7, 6YBW, 7WTX, 6QZP, 7K5I, 7WU0, 6ZMI, 7QVP, 6OM0, 6Y2L, 6G53, 6MTD, 6ZV6, 6Y0G, 7MQA, 5T2C, 5VYC, 6XA1, 6ZXH, 5LKS, 7WTT, 5OA3, 6ZXG, 6OLG, 7WTU, 6IP8, 6Z6N, 7MQ9, 7QP7, 6ZMW, 6ZN5, 6Z6M, 7MQ8, 6IP6, 6G5I, 7TQL

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC9 N	13	SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane] (R-COV-9729325) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus] (R-COV-9729339) N [plasma membrane] (R-COV-9694356) SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol] (R-COV-9756489) N [cytosol] (R-COV-9694300) p-S188,206-N [cytosol] (R-COV-9729324) p-8S-N [cytosol] (R-COV-9729335) p-8S,2T-N [cytosol] (R-COV-9729277) p-11S,2T-N [cytosol] (R-COV-9729264) p-11S,2T-metR95,177-N [cytosol] (R-COV-9729308) ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729275) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9729341) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729340)	0.643	4
UniProt:Q99558 MAP3K14	5	p-T559-MAP3K14 [cytosol] (R-HSA-5668531) K48polyUb-NIK [cytosol] (R-HSA-5668525) Active NIK [cytosol] (R-HSA-5607646) MAP3K14 [cytosol] (R-HSA-168189) p-MAP3K14 [cytosol] (R-HSA-168187)	0.564	2
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4
UniProt:P63244 RACK1	1	GNB2L1 [cytosol] (R-HSA-5626956)	0.495	2
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	5

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