Reactome | RBM28 [nucleoplasm]

RBM28 [nucleoplasm]

Stable Identifier

R-HSA-6791192

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

RNA-binding protein 28, RBM28_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9NW13 RBM28

Gene Names

RBM28

Chain

initiator methionine:, chain:2-759

Reference Genes

BioGPS Gene:55131 RBM28

COSMIC (genes):RBM28 RBM28

CTD Gene:55131 RBM28

dbSNP Gene:55131 RBM28

ENSEMBL:ENSG00000106344 RBM28

ENSEMBL_homo_sapiens_GENE:ENSG00000106344.8 RBM28

HGNC:21863 RBM28

KEGG Gene (Homo sapiens):55131 RBM28

Monarch:55131 RBM28

NCBI Gene:55131 RBM28

OMIM:612074 RBM28

UCSC:Q9NW13 RBM28

Reference Transcript

Other Identifiers

11744629_at

11752936_a_at

11756968_a_at

17062639

17118305

218593_PM_at

218593_at

231844_PM_at

231844_at

3071606

3071607

3071608

3071609

3071610

3071611

3071612

3071613

3071614

3071615

3071616

3071617

3071618

3071619

3071620

3071621

3071622

3071623

3071631

3071632

3071633

3071634

3071635

3071637

3071638

3071639

3071640

3071641

3071642

3071643

3071644

3071645

3071646

3071647

3071648

3071649

3071650

3071651

3071652

3071653

3071654

3071655

3071656

3071657

3071658

47815_at

51989_at

55131

81347_at

8142770

8142774

A_23_P168629

A_23_P336218

A_23_P393697

A_33_P3333050

A_33_P3628481

GE470391

GE55773

GE82294

GO:0003676

GO:0003723

GO:0005634

GO:0005681

GO:0005730

GO:0006397

GO:0008380

GO:0016071

GO:0043226

HMNXSV003002610

HMNXSV003022840

Hs.156828.0.S1_3p_at

ILMN_1660412

ILMN_1793033

PH_hs_0014131

PH_hs_0028595

PH_hs_0029257

TC07001843.hg

TC07001844.hg

TC07003159.hg

g8922387_3p_at

p25453

This entity regulates

Positively

45S pre-rRNA is nucleolytically processed at site 2 (site 2b) to yield 30S pre-rRNA and 32S pre-rRNA (Homo sapiens)

Cross References

RefSeq

NP_060547.2, NP_001159607.1

OpenTargets

ENSG00000106344

HPA

ENSG00000106344-RBM28

GeneCards

Q9NW13

Ensembl

ENSP00000390517, ENSP00000223073, ENST00000223073, ENSG00000106344, ENST00000415472

PRO

Q9NW13

Pharos - Targets

Q9NW13

Orphanet

17334

Interactors (39)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC9 N	13	SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane] (R-COV-9729325) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus] (R-COV-9729339) N [plasma membrane] (R-COV-9694356) SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol] (R-COV-9756489) N [cytosol] (R-COV-9694300) p-S188,206-N [cytosol] (R-COV-9729324) p-8S-N [cytosol] (R-COV-9729335) p-8S,2T-N [cytosol] (R-COV-9729277) p-11S,2T-N [cytosol] (R-COV-9729264) p-11S,2T-metR95,177-N [cytosol] (R-COV-9729308) ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729275) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9729341) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729340)	0.725	4
UniProt:P06748 NPM1	11	monoSUMO1-K263-NPM1 [nucleoplasm] (R-HSA-4086039) polySUMO2,3-K263-NPM1 [nucleoplasm] (R-HSA-4086056) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm] (R-HSA-9725010) NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol] (R-HSA-9730703) NPM1(1-117)-ALK(1068-1620) fusion [cytosol] (R-HSA-9730697) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9699861) NPM1(1-117)-ALK(1058-1620) fusion [cytosol] (R-HSA-9699834) NPM1 [granular component] (R-HSA-9017702) NPM1 [nucleoplasm] (R-HSA-606320) NPM1 [cytosol] (R-HSA-3008211) p-S4-NPM1 [cytosol] (R-HSA-6801679)	0.615	3
UniProt:P62753 RPS6	4	RPS6 [nucleoplasm] (R-HSA-6790606) 3OHR147-RPS6 [cytosol] (R-HSA-9629876) p-5S-RPS6 [cytosol] (R-HSA-165727) RPS6 [cytosol] (R-HSA-72381)	0.569	3
UniProt:P46087 NOP2	1	NOP2 [nucleoplasm] (R-HSA-6790922)	0.564	3
UniProt:O76021 RL1D1			0.564	2
UniProt:P61513 RPL37A	1	RPL37A [cytosol] (R-HSA-72468)	0.527	2
UniProt:P62888 RPL30	1	RPL30 [cytosol] (R-HSA-72452)	0.527	3
UniProt:P36578 RPL4	1	RPL4 [cytosol] (R-HSA-72474)	0.527	3
UniProt:P42696 RBM34			0.527	4
UniProt:Q15020 SART3			0.527	3
UniProt:Q9NZM5 NOP53			0.527	3
UniProt:P51608 MECP2			0.527	3
UniProt:P50914 RPL14	1	RPL14 [cytosol] (R-HSA-72414)	0.527	2
UniProt:Q02543 RPL18A	1	RPL18A [cytosol] (R-HSA-72422)	0.527	2
UniProt:Q9BXY0 MAK16			0.527	3
UniProt:P62263 RPS14	2	RPS14 [nucleoplasm] (R-HSA-6790669) RPS14 [cytosol] (R-HSA-72333)	0.527	2
UniProt:P84098 RPL19	1	RPL19 [cytosol] (R-HSA-72424)	0.527	2
UniProt:Q9UHB9 SRP68	1	SRP68 [cytosol] (R-HSA-445234)	0.527	2
UniProt:O43159 RRP8	1	RRP8 [nucleoplasm] (R-HSA-427524)	0.527	3
UniProt:Q8IXZ2 ZC3H3			0.527	2
UniProt:Q07020 RPL18	1	RPL18 [cytosol] (R-HSA-72420)	0.527	2
UniProt:P46779 RPL28	1	RPL28 [cytosol] (R-HSA-72444)	0.527	2
UniProt:P78362 SRPK2	1	SRPK2 [cytosol] (R-HSA-9729332)	0.527	2
UniProt:Q9H9Z2 LIN28A	1	LIN28A [cytosol] (R-HSA-500391)	0.527	2
UniProt:Q15646 OASL	1	OASL [cytosol] (R-HSA-1015678)	0.527	3
UniProt:Q9BYG3 MK67I			0.527	2
UniProt:Q96HE9 PRR11			0.527	2
UniProt:Q9BSG1 ZNF2	1	ZNF2 [nucleoplasm] (R-HSA-975031)	0.527	2
UniProt:P10412 H1-4	1	HIST1H1E [nucleoplasm] (R-HSA-211251)	0.527	3
UniProt:Q9P0M6 H2AW			0.527	2
UniProt:Q1ED39 KNOP1			0.527	2
UniProt:Q9UPE1 SRPK3			0.527	2
UniProt:P10074 TZAP			0.527	2
UniProt:Q15397 PUM3			0.527	4
UniProt:Q9BWF3 RBM4	1	RBM4 [cytosol] (R-HSA-8878898)	0.527	2
UniProt:P01127 PDGFB	8	PDGFB (82-190) [extracellular region] (R-HSA-184201) PDGFB(82-241) [extracellular region] (R-HSA-381904) PDGFB(1-241) [endoplasmic reticulum lumen] (R-HSA-381903) PDGFB(1-241) [Golgi membrane] (R-HSA-380740) PDGFB(1-81) [Golgi lumen] (R-HSA-389058) PDGFB(191-241) [Golgi lumen] (R-HSA-396945) PDGFB(21-81) [platelet alpha granule lumen] (R-HSA-184200) PDGFB(82-241) [platelet alpha granule lumen] (R-HSA-387075)	0.527	2
UniProt:Q6ZN17 LN28B			0.483	2
UniProt:Q9NR30 DDX21	1	DDX21 [nucleoplasm] (R-HSA-5250652)	0.483	2
UniProt:Q8WYQ5 DGCR8	1	DGCR8 [nucleoplasm] (R-HSA-1482509)	0.483	3

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