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RBM28 [nucleoplasm]
Stable Identifier
R-HSA-6791192
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
RNA-binding protein 28, RBM28_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q9UHB9 SRP68
Expand all
Metabolism of RNA (Homo sapiens)
rRNA processing (Homo sapiens)
rRNA processing in the nucleus and cytosol (Homo sapiens)
Major pathway of rRNA processing in the nucleolus and cytosol (Homo sapiens)
45S pre-rRNA is nucleolytically processed at site 2 (site 2b) to yield 30S pre-rRNA and 32S pre-rRNA (Homo sapiens)
RBM28 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NW13 RBM28
Gene Names
RBM28
Chain
initiator methionine:, chain:2-759
Reference Genes
BioGPS Gene:55131 RBM28
COSMIC (genes):RBM28 RBM28
CTD Gene:55131 RBM28
dbSNP Gene:55131 RBM28
ENSEMBL:ENSG00000106344 RBM28
HGNC:21863 RBM28
Monarch:55131 RBM28
NCBI Gene:55131 RBM28
OMIM:612074 RBM28
UCSC:Q9NW13 RBM28
Reference Transcript
RefSeq:NM_001166135.1 RBM28
RefSeq:NM_018077.2 RBM28
Other Identifiers
11744629_at
11752936_a_at
11756968_a_at
17062639
17118305
218593_PM_at
218593_at
231844_PM_at
231844_at
3071606
3071607
3071608
3071609
3071610
3071611
3071612
3071613
3071614
3071615
3071616
3071617
3071618
3071619
3071620
3071621
3071622
3071623
3071627
3071631
3071632
3071633
3071634
3071635
3071637
3071638
3071639
3071640
3071641
3071642
3071643
3071644
3071645
3071646
3071647
3071648
3071649
3071650
3071651
3071652
3071653
3071654
3071655
3071656
3071657
3071658
3071660
3071662
3071664
3071666
3071668
3071670
47815_at
51989_at
55131
81347_at
8142770
8142774
A_23_P168629
A_23_P336218
A_23_P393697
A_33_P3333050
A_33_P3628481
GE470391
GE55773
GE82294
GO:0003676
GO:0003723
GO:0003729
GO:0005515
GO:0005634
GO:0005681
GO:0005730
GO:0006397
GO:0008380
GO:0016071
GO:0043226
HMNXSV003002610
HMNXSV003022840
Hs.156828.0.S1_3p_at
ILMN_1660412
ILMN_1793033
PH_hs_0014131
PH_hs_0028595
PH_hs_0029257
TC07001843.hg
TC07001844.hg
TC07003159.hg
g8922387_3p_at
p25453
This entity regulates
Positively
45S pre-rRNA is nucleolytically processed at site 2 (site 2b) to yield 30S pre-rRNA and 32S pre-rRNA
(Homo sapiens)
Cross References
OpenTargets
ENSG00000106344
ENSEMBL
ENST00000223073
,
ENST00000415472
,
ENSP00000390517
,
ENSP00000223073
HPA
ENSG00000106344-RBM28
PRO
Q9NW13
Pharos - Targets
Q9NW13
GlyGen
Q9NW13
Orphanet
RBM28
Interactors (39)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P0DTC9 N
13
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729340)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9729341)
ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729275)
p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729308)
p-11S,2T-N [cytosol]
(R-COV-9729264)
p-8S,2T-N [cytosol]
(R-COV-9729277)
p-8S-N [cytosol]
(R-COV-9729335)
p-S188,206-N [cytosol]
(R-COV-9729324)
N [cytosol]
(R-COV-9694300)
SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol]
(R-COV-9756489)
N [plasma membrane]
(R-COV-9694356)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus]
(R-COV-9729339)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane]
(R-COV-9729325)
0.725
4
UniProt:P06748 NPM1
11
NPM1 [cytosol]
(R-HSA-3008211)
p-S4-NPM1 [cytosol]
(R-HSA-6801679)
NPM1 [nucleoplasm]
(R-HSA-606320)
NPM1 [granular component]
(R-HSA-9017702)
NPM1(1-117)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9699834)
NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9699861)
NPM1(1-117)-ALK(1068-1620) fusion [cytosol]
(R-HSA-9730697)
NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol]
(R-HSA-9730703)
NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm]
(R-HSA-9725010)
polySUMO2,3-K263-NPM1 [nucleoplasm]
(R-HSA-4086056)
monoSUMO1-K263-NPM1 [nucleoplasm]
(R-HSA-4086039)
0.615
3
UniProt:P62753 RPS6
4
RPS6 [cytosol]
(R-HSA-72381)
p-5S-RPS6 [cytosol]
(R-HSA-165727)
3OHR147-RPS6 [cytosol]
(R-HSA-9629876)
RPS6 [nucleoplasm]
(R-HSA-6790606)
0.569
3
UniProt:P46087 NOP2
1
NOP2 [nucleoplasm]
(R-HSA-6790922)
0.564
3
UniProt:O76021 RL1D1
0.564
2
UniProt:P62263 RPS14
2
RPS14 [cytosol]
(R-HSA-72333)
RPS14 [nucleoplasm]
(R-HSA-6790669)
0.527
2
UniProt:Q9H9Z2 LIN28A
1
LIN28A [cytosol]
(R-HSA-500391)
0.527
2
UniProt:Q15646 OASL
1
OASL [cytosol]
(R-HSA-1015678)
0.527
3
UniProt:O43159 RRP8
1
RRP8 [nucleoplasm]
(R-HSA-427524)
0.527
3
UniProt:Q9BYG3 MK67I
0.527
2
UniProt:Q96HE9 PRR11
0.527
2
UniProt:Q9BSG1 ZNF2
1
ZNF2 [nucleoplasm]
(R-HSA-975031)
0.527
2
UniProt:P10412 H1-4
1
HIST1H1E [nucleoplasm]
(R-HSA-211251)
0.527
3
UniProt:Q9P0M6 H2AW
0.527
2
UniProt:Q1ED39 KNOP1
0.527
2
UniProt:Q9UPE1 SRPK3
0.527
2
UniProt:P10074 TZAP
0.527
2
UniProt:Q15397 PUM3
0.527
4
UniProt:Q9BWF3 RBM4
1
RBM4 [cytosol]
(R-HSA-8878898)
0.527
2
UniProt:P01127 PDGFB
8
PDGFB(82-241) [platelet alpha granule lumen]
(R-HSA-387075)
PDGFB(21-81) [platelet alpha granule lumen]
(R-HSA-184200)
PDGFB(191-241) [Golgi lumen]
(R-HSA-396945)
PDGFB(1-81) [Golgi lumen]
(R-HSA-389058)
PDGFB(1-241) [Golgi membrane]
(R-HSA-380740)
PDGFB(1-241) [endoplasmic reticulum lumen]
(R-HSA-381903)
PDGFB(82-241) [extracellular region]
(R-HSA-381904)
PDGFB (82-190) [extracellular region]
(R-HSA-184201)
0.527
2
UniProt:P78362 SRPK2
1
SRPK2 [cytosol]
(R-HSA-9729332)
0.527
2
UniProt:P46779 RPL28
1
RPL28 [cytosol]
(R-HSA-72444)
0.527
2
UniProt:Q07020 RPL18
1
RPL18 [cytosol]
(R-HSA-72420)
0.527
2
UniProt:Q8IXZ2 ZC3H3
0.527
2
UniProt:Q9UHB9 SRP68
1
SRP68 [cytosol]
(R-HSA-445234)
0.527
2
UniProt:P84098 RPL19
1
RPL19 [cytosol]
(R-HSA-72424)
0.527
2
UniProt:Q9BXY0 MAK16
0.527
3
UniProt:Q02543 RPL18A
1
RPL18A [cytosol]
(R-HSA-72422)
0.527
2
UniProt:P50914 RPL14
1
RPL14 [cytosol]
(R-HSA-72414)
0.527
2
UniProt:P51608 MECP2
0.527
3
UniProt:Q9NZM5 NOP53
0.527
3
UniProt:Q15020 SART3
0.527
3
UniProt:P42696 RBM34
0.527
4
UniProt:P36578 RPL4
1
RPL4 [cytosol]
(R-HSA-72474)
0.527
3
UniProt:P62888 RPL30
1
RPL30 [cytosol]
(R-HSA-72452)
0.527
3
UniProt:P61513 RPL37A
1
RPL37A [cytosol]
(R-HSA-72468)
0.527
2
UniProt:Q9NR30 DDX21
1
DDX21 [nucleoplasm]
(R-HSA-5250652)
0.483
2
UniProt:Q8WYQ5 DGCR8
1
DGCR8 [nucleoplasm]
(R-HSA-1482509)
0.483
3
UniProt:Q6ZN17 LN28B
0.483
2
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