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RPS16 [nucleoplasm]
Stable Identifier
R-HSA-6791196
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
40S ribosomal protein S16, RS16_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q9H6S0 YTDC2
Expand all
Metabolism of RNA (Homo sapiens)
rRNA processing (Homo sapiens)
rRNA processing in the nucleus and cytosol (Homo sapiens)
Major pathway of rRNA processing in the nucleolus and cytosol (Homo sapiens)
30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA (Homo sapiens)
RPS16 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P62249 RPS16
Gene Names
RPS16
Chain
initiator methionine:, chain:2-146
Reference Genes
BioGPS Gene:6217 RPS16
COSMIC (genes):RPS16 RPS16
CTD Gene:6217 RPS16
dbSNP Gene:6217 RPS16
ENSEMBL:ENSG00000105193 RPS16
ENSEMBL_homo_sapiens_GENE:ENSG00000105193.9 RPS16
HGNC:10396 RPS16
KEGG Gene (Homo sapiens):6217 RPS16
Monarch:6217 RPS16
NCBI Gene:6217 RPS16
OMIM:603675 RPS16
UCSC:P62249 RPS16
Reference Transcript
RefSeq:NM_001020.5 RPS16
Other Identifiers
11758289_x_at
16872229
201258_PM_at
201258_at
213890_PM_x_at
213890_x_at
226131_PM_s_at
226131_s_at
38061_at
3862019
3862020
3862021
3862022
3862024
3862026
3862029
3862030
3862031
3862032
6217
8036737
A_23_P208850
GE80063
GE88165
GO:0000462
GO:0002181
GO:0003723
GO:0003735
GO:0005198
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0005829
GO:0005840
GO:0005925
GO:0006364
GO:0006412
GO:0015935
GO:0016020
GO:0022626
GO:0022627
GO:0032040
GO:0042254
GO:0042274
GO:0043226
GO:0045202
GO:0070062
GO:1990830
GO:1990904
HMNXSV003030940
Hs.80617.2.S1_3p_x_at
ILMN_1651850
M60854_at
TC19001521.hg
g4506690_3p_a_at
Participates
as a component of
18SE pre-40S particle [nucleoplasm] (Homo sapiens)
This entity regulates
Positively
30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA
(Homo sapiens)
Other forms of this molecule
RPS16 [cytosol]
Inferred To
Homologues of RPS16 [nucleoplasm]
(Saccharomyces cerevisiae)
Homologues of RPS16 [nucleoplasm]
(Schizosaccharomyces pombe)
Rps16 [nucleoplasm]
(Mus musculus)
Rps16 [nucleoplasm]
(Rattus norvegicus)
rps16 [nucleoplasm]
(Danio rerio)
rps16 [nucleoplasm]
(Dictyostelium discoideum)
rps16 [nucleoplasm]
(Xenopus tropicalis)
rps-16 [nucleoplasm]
(Caenorhabditis elegans)
rps1601 [nucleoplasm]
(Schizosaccharomyces pombe)
RPS16 [nucleoplasm]
(Bos taurus)
RPS16 [nucleoplasm]
(Canis familiaris)
RPS16 [nucleoplasm]
(Gallus gallus)
RPS16 [nucleoplasm]
(Plasmodium falciparum)
RPS16 [nucleoplasm]
(Sus scrofa)
RPS16B [nucleoplasm]
(Saccharomyces cerevisiae)
RPS16A [nucleoplasm]
(Saccharomyces cerevisiae)
RpS16 [nucleoplasm]
(Drosophila melanogaster)
rps1602 [nucleoplasm]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_001011.1
OpenTargets
ENSG00000105193
HPA
ENSG00000105193-RPS16
GeneCards
P62249
Ensembl
ENSG00000105193
,
ENST00000251453
,
ENSP00000251453
PRO
P62249
Pharos - Targets
P62249
PDB
6ZXD
,
6G4W
,
8PPK
,
6ZME
,
6Y2L
,
6ZXE
,
4UG0
,
8JDM
,
8T4S
,
8IFD
,
6G5I
,
6OLI
,
6XA1
,
6G4S
,
7WU0
,
6G18
,
7WTZ
,
5T2C
,
8JDL
,
6G51
,
6ZXH
,
6ZMO
,
7XNY
,
7TQL
,
6IP5
,
6FEC
,
6ZMT
,
6ZLW
,
6Z6N
,
7WTW
,
7MQ9
,
7R4X
,
6Z6M
,
7WTV
,
6ZXF
,
8OZ0
,
6ZXG
,
6ZMI
,
8JDJ
,
8PPL
,
6YBS
,
7MQ8
,
7QP7
,
6OM7
,
7QP6
,
7A09
,
7K5I
,
6Y0G
,
5VYC
,
6OM0
,
6ZVJ
,
8G5Y
,
6ZON
,
6QZP
,
6OLZ
,
6G53
,
8G60
,
5AJ0
,
6IP6
,
8G6J
,
7MQA
,
8GLP
,
6ZM7
,
6IP8
,
5LKS
,
5OA3
,
6ZVH
,
6ZOL
,
6ZN5
,
6ZMW
,
7WTX
,
6ZOJ
,
5A2Q
,
5FLX
,
6G5H
,
8Y0X
,
4V6X
,
8JDK
,
6OLG
,
7WTT
,
6ZP4
,
6ZUO
,
7XNX
,
8Y0W
,
6Y57
,
6ZV6
,
8G61
,
6OLE
,
8IFE
,
6OLF
,
7WTU
,
6Z6L
Interactors (62)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P63244 RACK1
1
GNB2L1 [cytosol]
(R-HSA-5626956)
0.715
5
UniProt:P39019 RPS19
2
RPS19 [nucleoplasm]
(R-HSA-6798710)
RPS19 [cytosol]
(R-HSA-72343)
0.669
4
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.642
4
UniProt:P26196 DDX6
1
DDX6 [cytosol]
(R-HSA-430032)
0.615
4
UniProt:Q9NX58 LYAR
0.564
2
UniProt:O60739 EIF1B
0.564
2
UniProt:O76021 RL1D1
0.527
2
UniProt:P61254 RPL26
1
RPL26 [cytosol]
(R-HSA-72436)
0.527
2
UniProt:Q9BYJ9 YTHD1
0.527
2
UniProt:P62263 RPS14
2
RPS14 [nucleoplasm]
(R-HSA-6790669)
RPS14 [cytosol]
(R-HSA-72333)
0.527
2
UniProt:P84098 RPL19
1
RPL19 [cytosol]
(R-HSA-72424)
0.527
4
UniProt:Q8N9T8 KRI1
0.527
2
UniProt:Q9Y5S9 RBM8A
2
RBM8A [cytosol]
(R-HSA-162462)
RBM8A [nucleoplasm]
(R-HSA-156659)
0.527
2
UniProt:P19320 VCAM1
1
VCAM1 [plasma membrane]
(R-HSA-197834)
0.527
4
UniProt:Q13895 BYSL
2
BYSL [nucleoplasm]
(R-HSA-6791526)
BYSL [cytosol]
(R-HSA-6791518)
0.527
4
UniProt:Q8IZH2 XRN1
1
XRN1 [cytosol]
(R-HSA-429835)
0.527
2
UniProt:Q15050 RRS1
0.527
2
UniProt:P62899 RPL31
1
RPL31 [cytosol]
(R-HSA-72454)
0.527
3
UniProt:P10412 H1-4
1
HIST1H1E [nucleoplasm]
(R-HSA-211251)
0.527
3
UniProt:Q5SSJ5 HP1B3
0.527
2
UniProt:P46783 RPS10
2
RPS10 [nucleoplasm]
(R-HSA-6798733)
RPS10 [cytosol]
(R-HSA-72325)
0.527
3
UniProt:Q13823 NOG2
0.527
2
UniProt:Q7L2Z9 CENPQ
2
CENPQ [nucleoplasm]
(R-HSA-606327)
CENPQ [cytosol]
(R-HSA-375298)
0.527
2
UniProt:Q7RTS1 BHA15
0.527
2
UniProt:P78316 NOP14
1
NOP14 [nucleoplasm]
(R-HSA-6790710)
0.527
3
UniProt:Q4G0J3 LARP7
0.527
3
UniProt:P08865 RPSA
2
RPSA [nucleoplasm]
(R-HSA-6798722)
RPSA [cytosol]
(R-HSA-72389)
0.527
2
UniProt:Q00839 HNRNPU
1
HNRNPU [nucleoplasm]
(R-HSA-71953)
0.527
2
UniProt:Q66K89 E4F1
0.527
2
UniProt:Q15843 NEDD8
8
C111-AcM-UBE2M-G76-NEDD8 [nucleoplasm]
(R-HSA-8952504)
NEDD8 [nucleoplasm]
(R-HSA-8955926)
C116-AcM-UBE2F-G76-NEDD8 [cytosol]
(R-HSA-8951739)
NEDD8(77-81) [cytosol]
(R-HSA-6782654)
NEDD8(1-81) [cytosol]
(R-HSA-5690794)
C237-UBA3-G76-NEDD8 [cytosol]
(R-HSA-8951647)
NEDD8 [cytosol]
(R-HSA-416969)
C111-AcM-UBE2M-G76-NEDD8 [cytosol]
(R-HSA-4419895)
0.527
2
UniProt:Q6PCB5 RSBNL
0.527
2
UniProt:Q7Z2T5 TRM1L
0.527
2
UniProt:P16104 H2AFX
7
Me2sR4-H2AFX [nucleoplasm]
(R-HSA-5218317)
H2AFX [nucleoplasm]
(R-HSA-56151)
p-Y143-H2AFX [nucleoplasm]
(R-HSA-5683942)
p-S140,Y143-H2AFX [nucleoplasm]
(R-HSA-5683953)
p-S140-H2AFX [nucleoplasm]
(R-HSA-75170)
K63PolyUb-K14,K16,p-S140-H2AFX [nucleoplasm]
(R-HSA-5682847)
H2AFX [extracellular region]
(R-HSA-977583)
0.527
2
UniProt:Q15022 SUZ12
2
SUZ12 [nucleoplasm]
(R-HSA-212217)
monoSUMO1-K75-SUZ12 [nucleoplasm]
(R-HSA-4615932)
0.527
2
UniProt:P62841 RPS15
2
RPS15 [nucleoplasm]
(R-HSA-6798706)
RPS15 [cytosol]
(R-HSA-72335)
0.527
2
UniProt:Q2NL82 TSR1
2
TSR1 [nucleoplasm]
(R-HSA-6791574)
TSR1 [cytosol]
(R-HSA-6791570)
0.527
4
UniProt:P62280 RPS11
2
RPS11 [nucleoplasm]
(R-HSA-6791212)
RPS11 [cytosol]
(R-HSA-72327)
0.527
3
UniProt:P62241 RPS8
2
RPS8 [nucleoplasm]
(R-HSA-6791203)
RPS8 [cytosol]
(R-HSA-72385)
0.527
2
UniProt:P23396 RPS3
2
RPS3 [nucleoplasm]
(R-HSA-6798714)
RPS3 [cytosol]
(R-HSA-72369)
0.527
3
UniProt:P27635 RPL10
1
RPL10 [cytosol]
(R-HSA-72402)
0.527
2
UniProt:P62847 RPS24
2
RPS24 [nucleoplasm]
(R-HSA-6791186)
RPS24 [cytosol]
(R-HSA-72355)
0.527
2
UniProt:Q14684 RRP1B
0.527
2
UniProt:Q9H9Y2 RPF1
0.527
2
UniProt:P62750 RPL23A
1
RPL23A [cytosol]
(R-HSA-72432)
0.527
2
UniProt:Q6P158 DHX57
0.527
2
UniProt:P62277 RPS13
2
RPS13 [nucleoplasm]
(R-HSA-6791198)
RPS13 [cytosol]
(R-HSA-72331)
0.527
2
UniProt:Q9H6S0 YTDC2
0.527
2
UniProt:P42766 RPL35
1
RPL35 [cytosol]
(R-HSA-72460)
0.527
3
UniProt:Q9ULX3 NOB1
2
NOB1 [nucleoplasm]
(R-HSA-6791536)
NOB1 [cytosol]
(R-HSA-6791524)
0.527
3
UniProt:Q9Y3B2 EXOSC1
2
EXOSC1 [nucleoplasm]
(R-HSA-6791578)
EXOSC1 [cytosol]
(R-HSA-429841)
0.527
2
UniProt:Q9BRT6 LLPH
0.527
2
UniProt:Q96KR1 ZFR
0.527
2
UniProt:Q9NR30 DDX21
1
DDX21 [nucleoplasm]
(R-HSA-5250652)
0.527
2
UniProt:P49711 CTCF
1
CTCF [nucleoplasm]
(R-HSA-3782562)
0.527
2
UniProt:P62753 RPS6
4
RPS6 [nucleoplasm]
(R-HSA-6790606)
3OHR147-RPS6 [cytosol]
(R-HSA-9629876)
p-5S-RPS6 [cytosol]
(R-HSA-165727)
RPS6 [cytosol]
(R-HSA-72381)
0.527
2
UniProt:P15880 RPS2
3
RPS2 [nucleoplasm]
(R-HSA-6790655)
Me2aR-RPS2 [cytosol]
(R-HSA-8879138)
RPS2 [cytosol]
(R-HSA-72347)
0.527
3
UniProt:Q9NQT4 EXOSC5
2
EXOSC5 [cytosol]
(R-HSA-429889)
EXOSC5 [nucleoplasm]
(R-HSA-6791550)
0.527
2
UniProt:Q8NHQ9 DDX55
0.483
2
UniProt:O75821 EIF3G
1
EIF3G [cytosol]
(R-HSA-72538)
0.483
3
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.483
12
UniProt:P03372 ESR1
10
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S167-ESR1 [nucleoplasm]
(R-HSA-9841867)
p-S167-ESR1 [cytosol]
(R-HSA-9841254)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
ESR1 [nucleoplasm]
(R-HSA-446168)
ESR1 [cytosol]
(R-HSA-9020968)
0.462
2
UniProt:Q92731 ESR2
5
PalmS-ESR2 [cytosol]
(R-HSA-9020979)
Me-PalmS-ESR2 [plasma membrane]
(R-HSA-9637787)
PalmS-ESR2 [plasma membrane]
(R-HSA-9021059)
ESR2 [nucleoplasm]
(R-HSA-446165)
ESR2 [cytosol]
(R-HSA-9020970)
0.462
2
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