Reactome | RPS27L [nucleoplasm]

RPS27L [nucleoplasm]

Stable Identifier

R-HSA-6791197

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

40S ribosomal protein S27-like, RS27L_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q71UM5 RPS27L

Gene Names

RPS27L

Chain

chain:1-84

Reference Genes

BioGPS Gene:51065 RPS27L

COSMIC (genes):RPS27L RPS27L

CTD Gene:51065 RPS27L

dbSNP Gene:51065 RPS27L

ENSEMBL:ENSG00000185088 RPS27L

ENSEMBL:ENSG00000185088.14 RPS27L

HGNC:18476 RPS27L

KEGG Gene (Homo sapiens):51065 RPS27L

Monarch:51065 RPS27L

NCBI Gene:51065 RPS27L

OMIM:612055 RPS27L

UCSC:Q71UM5 RPS27L

Reference Transcript

RefSeq:NM_015920.3 RPS27L

Other Identifiers

11744350_a_at

11759492_at

218007_PM_s_at

218007_s_at

238935_PM_at

238935_at

3628463

3628465

3628467

3628468

3628470

3628471

3628472

3628475

3628476

3628477

3628480

51065

54356_at

56410_at

7989493

A_23_P14734

A_24_P917549

GE58617

GE893033

GO:0000028

GO:0000278

GO:0003723

GO:0003735

GO:0005198

GO:0005515

GO:0005634

GO:0005829

GO:0005840

GO:0006412

GO:0006919

GO:0006978

GO:0008494

GO:0008656

GO:0012501

GO:0022627

GO:0023052

GO:0031571

GO:0042254

GO:0042771

GO:0043226

GO:0045182

GO:0045727

GO:0046872

GO:0065003

GO:0098772

GO:1990904

HMNXSV003022681

Hs.293947.0.A1_3p_at

ILMN_1712678

ILMN_2126802

PH_hs_0003317

PH_hs_0006023

g7705705_3p_at

g7705705_3p_s_at

Participates

as a candidate of

RPS27,RPS27L [nucleoplasm] (Homo sapiens)

This entity regulates

Positively

30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA (Homo sapiens)

Other forms of this molecule

RPS27L [cytosol]

Inferred To

Rps27l [nucleoplasm] (Mus musculus)

Rps27l [nucleoplasm] (Rattus norvegicus)

rps27 [nucleoplasm] (Dictyostelium discoideum)

rps27 [nucleoplasm] (Schizosaccharomyces pombe)

RPS27B [nucleoplasm] (Saccharomyces cerevisiae)

rps-27 [nucleoplasm] (Caenorhabditis elegans)

RPS27L [nucleoplasm] (Bos taurus)

RPS27L [nucleoplasm] (Canis familiaris)

RPS27L [nucleoplasm] (Danio rerio)

RPS27L [nucleoplasm] (Gallus gallus)

RPS27L [nucleoplasm] (Sus scrofa)

RpS27 [nucleoplasm] (Drosophila melanogaster)

RPS27 [nucleoplasm] (Plasmodium falciparum)

Cross References

RefSeq

NP_057004.1

OpenTargets

ENSG00000185088

HPA

ENSG00000185088-RPS27L

GeneCards

Q71UM5

Ensembl

ENSG00000185088, ENSP00000331019, ENST00000330964

PRO

Q71UM5

Pharos - Targets

Q71UM5

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q00987 MDM2	11	PolyUb-MDM2 [nucleoplasm] (R-HSA-6782472) monoSUMO1-K182-MDM2 [nucleoplasm] (R-HSA-3000408) MDM2 [plasma membrane] (R-HSA-416843) MDM2 [endocytic vesicle membrane] (R-HSA-416849) p-5S,T-MDM2 [nucleoplasm] (R-HSA-6804954) PolyUb,p-S166,S188-MDM2 [nucleoplasm] (R-HSA-6795669) p-S166,S188,T218-MDM2 [nucleoplasm] (R-HSA-6792862) MDM2 [nucleoplasm] (R-HSA-69486) MDM2 [cytosol] (R-HSA-198644) p-S166,S188-MDM2 [cytosol] (R-HSA-198638) p-S166,S188-MDM2 [nucleoplasm] (R-HSA-6793669)	0.619	6
UniProt:Q16659 MAPK6	6	ub-MAPK6 [cytosol] (R-HSA-5687000) MAPK6 [cytosol] (R-HSA-5686979) p-S189 MAPK6 [cytosol] (R-HSA-5687019) p-S189 MAPK6 [nucleoplasm] (R-HSA-5687015) MAPK6 [nucleoplasm] (R-HSA-5692686) p-3S,T MAPK6 [nucleoplasm] (R-HSA-5692665)	0.527	2
UniProt:Q92731 ESR2	5	PalmS-ESR2 [cytosol] (R-HSA-9020979) PalmS-ESR2 [plasma membrane] (R-HSA-9021059) Me-PalmS-ESR2 [plasma membrane] (R-HSA-9637787) ESR2 [nucleoplasm] (R-HSA-446165) ESR2 [cytosol] (R-HSA-9020970)	0.462	2

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