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PES1 [nucleoplasm]
Stable Identifier
R-HSA-6791207
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
fullName evidence="3"Pescadillo homolog, PESC_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
rRNA processing (Homo sapiens)
rRNA processing in the nucleus and cytosol (Homo sapiens)
Major pathway of rRNA processing in the nucleolus and cytosol (Homo sapiens)
32S pre-rRNA is nucleolytically processed at site 4 (4a) to yield 12S pre-rRNA and 28S rRNA (Homo sapiens)
32S pre-rRNA:Rix1:LAS1L:NOL9:SENP3 [nucleoplasm] (Homo sapiens)
PeBoW complex [nucleoplasm] (Homo sapiens)
PES1 [nucleoplasm] (Homo sapiens)
GNL3:EBNA1BP2:DDX21:PES1 [nucleoplasm] (Homo sapiens)
PES1 [nucleoplasm] (Homo sapiens)
PeBoW complex [nucleoplasm] (Homo sapiens)
PES1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O00541 PES1
Gene Names
PES1
Chain
chain:1-588
Reference Genes
BioGPS Gene:23481 PES1
COSMIC (genes):PES1 PES1
CTD Gene:23481 PES1
dbSNP Gene:23481 PES1
ENSEMBL:ENSG00000100029 PES1
HGNC:8848 PES1
KEGG:hsa:23481 PES1
Monarch:23481 PES1
NCBI Gene:23481 PES1
OMIM:605819 PES1
UCSC:O00541 PES1
Reference Transcript
RefSeq:NM_001243225.1 PES1
RefSeq:NM_014303.3 PES1
Other Identifiers
11716242_a_at
16933931
202212_3p_at
202212_PM_at
202212_at
23481
236434_PM_at
236434_at
2743961
3162775
3957446
3957447
3957448
3957450
3957451
3957452
3957453
3957454
3957455
3957456
3957457
3957458
3957459
3957460
3957461
3957462
3957463
3957464
3957465
3957466
3957467
3957468
3957469
3957470
3957471
3957472
3957474
3957475
3957476
3957477
3957478
3957479
3957481
41869_at
57058_at
78120_at
8075406
A_23_P132260
A_23_P334555
GE61088
GE84212
GO:0000463
GO:0000466
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005730
GO:0005829
GO:0006364
GO:0008283
GO:0016020
GO:0030687
GO:0042254
GO:0042273
GO:0043021
GO:0043226
GO:0051726
GO:0070545
HMNXSV003031676
Hs.132037.0.A1_3p_at
ILMN_1656372
PH_hs_0022478
TC22000658.hg
TC22001300.hg
g7657454_3p_at
g7657454_3p_s_at
Participates
as a component of
GNL3:EBNA1BP2:DDX21:PES1 [nucleoplasm] (Homo sapiens)
PeBoW complex [nucleoplasm] (Homo sapiens)
Inferred To
Pes1 [nucleoplasm]
(Mus musculus)
Pes1 [nucleoplasm]
(Rattus norvegicus)
lpd-7 [nucleoplasm]
(Caenorhabditis elegans)
pes [nucleoplasm]
(Danio rerio)
pes1 [nucleoplasm]
(Xenopus tropicalis)
NOP7 [nucleoplasm]
(Saccharomyces cerevisiae)
PES1 [nucleoplasm]
(Bos taurus)
PES1 [nucleoplasm]
(Canis familiaris)
PES1 [nucleoplasm]
(Dictyostelium discoideum)
PES1 [nucleoplasm]
(Drosophila melanogaster)
PES1 [nucleoplasm]
(Gallus gallus)
PES1 [nucleoplasm]
(Sus scrofa)
ppp1 [nucleoplasm]
(Schizosaccharomyces pombe)
Cross References
OpenTargets
ENSG00000100029
ENSEMBL
ENSP00000334612
,
ENST00000354694
,
ENST00000335214
,
ENSP00000346725
,
ENSG00000100029
HPA
ENSG00000100029-PES1
GeneCards
PES1
PRO
O00541
Pharos - Targets
O00541
GlyGen
O00541
PDB
8FLE
,
8FKZ
,
8FLB
,
8INE
,
8FLD
,
8FKY
,
8FKT
,
8FKR
,
8FKS
,
8FKQ
,
8FLA
,
8FL7
,
8FKV
,
8FKP
,
8FKX
,
8FL6
,
8IR3
,
8FKU
,
8FKW
,
8IPY
,
8FL3
,
8FL4
,
8FL2
,
8INF
,
8IPX
,
2EP8
Interactors (10)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q14137 BOP1
1
BOP1 [nucleoplasm]
(R-HSA-6791206)
0.758
6
UniProt:P68400 CSNK2A1
2
CSNK2A1 [cytosol]
(R-HSA-201713)
CSNK2A1 [nucleoplasm]
(R-HSA-6805057)
0.725
4
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
3
UniProt:Q9HCG8 CWC22
1
CWC22 [nucleoplasm]
(R-HSA-8865956)
0.527
2
UniProt:Q9UHB7 AFF4
1
AFF4 [nucleoplasm]
(R-HSA-8932788)
0.527
2
UniProt:P42568 MLLT3
1
MLLT3 [nucleoplasm]
(R-HSA-8932789)
0.527
2
UniProt:O15047 SETD1A
1
SETD1A [nucleoplasm]
(R-HSA-3239027)
0.527
2
UniProt:Q08050 FOXM1
3
p-T611,S730,S739-FOXM1 [nucleoplasm]
(R-HSA-4088133)
p-T611-FOXM1 [nucleoplasm]
(R-HSA-4088026)
FOXM1 [nucleoplasm]
(R-HSA-4088019)
0.499
2
UniProt:P06748 NPM1
11
NPM1 [cytosol]
(R-HSA-3008211)
p-S4-NPM1 [cytosol]
(R-HSA-6801679)
NPM1 [nucleoplasm]
(R-HSA-606320)
NPM1 [granular component]
(R-HSA-9017702)
NPM1(1-117)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9699834)
NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9699861)
NPM1(1-117)-ALK(1068-1620) fusion [cytosol]
(R-HSA-9730697)
NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol]
(R-HSA-9730703)
NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm]
(R-HSA-9725010)
polySUMO2,3-K263-NPM1 [nucleoplasm]
(R-HSA-4086056)
monoSUMO1-K263-NPM1 [nucleoplasm]
(R-HSA-4086039)
0.483
2
UniProt:Q8WUA2 PPIL4
1
PPIL4 [nucleoplasm]
(R-HSA-8952113)
0.483
2
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