Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
PES1 [nucleoplasm]
Stable Identifier
R-HSA-6791207
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
fullName evidence="3"Pescadillo homolog, PESC_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
rRNA processing (Homo sapiens)
rRNA processing in the nucleus and cytosol (Homo sapiens)
Major pathway of rRNA processing in the nucleolus and cytosol (Homo sapiens)
32S pre-rRNA is nucleolytically processed at site 4 (4a) to yield 12S pre-rRNA and 28S rRNA (Homo sapiens)
32S pre-rRNA:Rix1:LAS1L:NOL9:SENP3 [nucleoplasm] (Homo sapiens)
PeBoW complex [nucleoplasm] (Homo sapiens)
PES1 [nucleoplasm] (Homo sapiens)
GNL3:EBNA1BP2:DDX21:PES1 [nucleoplasm] (Homo sapiens)
PES1 [nucleoplasm] (Homo sapiens)
PeBoW complex [nucleoplasm] (Homo sapiens)
PES1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O00541 PES1
Gene Names
PES1
Chain
chain:1-588
Reference Genes
BioGPS Gene:23481 PES1
COSMIC (genes):PES1 PES1
CTD Gene:23481 PES1
dbSNP Gene:23481 PES1
ENSEMBL:ENSG00000100029 PES1
ENSEMBL_homo_sapiens_GENE:ENSG00000100029.18 PES1
HGNC:8848 PES1
KEGG Gene (Homo sapiens):23481 PES1
Monarch:23481 PES1
NCBI Gene:23481 PES1
OMIM:605819 PES1
UCSC:O00541 PES1
Reference Transcript
RefSeq:NM_001243225.1 PES1
RefSeq:NM_014303.3 PES1
Other Identifiers
11716242_a_at
16933931
202212_3p_at
202212_PM_at
202212_at
23481
2743961
3162775
3957446
3957447
3957448
3957450
3957452
3957453
3957457
3957459
3957460
3957461
3957462
3957463
3957464
3957465
3957470
3957471
3957472
3957474
41869_at
57058_at
8075406
A_23_P132260
A_23_P334555
GE61088
GO:0000463
GO:0000466
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005730
GO:0005829
GO:0006364
GO:0008283
GO:0016020
GO:0030687
GO:0042254
GO:0042273
GO:0043021
GO:0043226
GO:0051726
GO:0070545
HMNXSV003031676
ILMN_1656372
PH_hs_0022478
TC22000658.hg
TC22001300.hg
g7657454_3p_at
g7657454_3p_s_at
Participates
as a component of
GNL3:EBNA1BP2:DDX21:PES1 [nucleoplasm] (Homo sapiens)
PeBoW complex [nucleoplasm] (Homo sapiens)
Inferred To
Pes1 [nucleoplasm]
(Mus musculus)
Pes1 [nucleoplasm]
(Rattus norvegicus)
lpd-7 [nucleoplasm]
(Caenorhabditis elegans)
pes [nucleoplasm]
(Danio rerio)
pes1 [nucleoplasm]
(Xenopus tropicalis)
NOP7 [nucleoplasm]
(Saccharomyces cerevisiae)
PES1 [nucleoplasm]
(Bos taurus)
PES1 [nucleoplasm]
(Canis familiaris)
PES1 [nucleoplasm]
(Dictyostelium discoideum)
PES1 [nucleoplasm]
(Drosophila melanogaster)
PES1 [nucleoplasm]
(Gallus gallus)
PES1 [nucleoplasm]
(Sus scrofa)
ppp1 [nucleoplasm]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_055118.1
,
NP_001230154.1
OpenTargets
ENSG00000100029
GeneCards
O00541
HPA
ENSG00000100029-PES1
Ensembl
ENSG00000100029
,
ENST00000354694
,
ENST00000335214
,
ENSP00000346725
,
ENSP00000334612
PRO
O00541
Pharos - Targets
O00541
Orphanet
24798
PDB
8FLA
,
8FL3
,
8IR3
,
8INE
,
8INF
,
8FKT
,
8FKP
,
8FL4
,
8FKU
,
2EP8
,
8FKV
,
8FKR
,
8FL6
,
8IPY
,
8FLB
,
8FKX
,
8IPX
,
8FKW
,
8FKQ
,
8FKZ
,
8FL2
,
8FLD
,
8FLE
,
8FL7
,
8FKY
,
8FKS
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q14137 BOP1
1
BOP1 [nucleoplasm]
(R-HSA-6791206)
0.597
4
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
3
UniProt:Q08050 FOXM1
3
p-T611,S730,S739-FOXM1 [nucleoplasm]
(R-HSA-4088133)
p-T611-FOXM1 [nucleoplasm]
(R-HSA-4088026)
FOXM1 [nucleoplasm]
(R-HSA-4088019)
0.499
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text