Reactome | C1D [nucleoplasm]

C1D [nucleoplasm]

Stable Identifier

R-HSA-6791515

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Nuclear nucleic acid-binding protein C1D, C1D_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q01780 EXOSC10

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External Reference Information

External Reference

UniProt:Q13901 C1D

Gene Names

C1D

Chain

chain:1-141

Reference Genes

BioGPS Gene:10438 C1D

COSMIC (genes):C1D C1D

CTD Gene:10438 C1D

dbSNP Gene:10438 C1D

ENSEMBL:ENSG00000197223 C1D

ENSEMBL_homo_sapiens_GENE:ENSG00000197223.12 C1D

HGNC:29911 C1D

KEGG Gene (Homo sapiens):10438 C1D

Monarch:10438 C1D

NCBI Gene:10438 C1D

OMIM:606997 C1D

UCSC:Q13901 C1D

Reference Transcript

Other Identifiers

10438

11718174_x_at

11748703_a_at

11748704_s_at

18670323

18670324

18670325

18670327

18670329

18670331

200056_PM_s_at

200056_s_at

2557558

2557559

2557560

2557561

2557562

2557563

2557564

2557565

2557566

2557567

2557568

2557569

2557574

2557578

3284162

3284163

3284164

3284165

3284166

3297355

3297356

3297357

3297359

3297484

3297490

39782_at

7893913

7893918

7894355

7894827

7895153

7932964

7934729

7934731

8052698

80643_at

A_23_P56590

A_23_P67992

GE60176

GO:0000176

GO:0000178

GO:0000460

GO:0003677

GO:0003714

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0006351

GO:0006355

GO:0006364

GO:0006915

GO:0010468

GO:0012501

GO:0016922

GO:0017053

GO:0042254

GO:0043226

GO:0045892

GO:0140110

HMNXSV003007741

ILMN_1762330

ILMN_2394613

TC02001938.hg

X95592_at

g5453582_3p_a_at

Participates

as a component of

EXOSC10:C1D:MPHOSPH6 [nucleoplasm] (Homo sapiens)

This entity regulates

Positively

12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA (Homo sapiens)

Inferred To

C1d [nucleoplasm] (Mus musculus)

Rrp47 [nucleoplasm] (Drosophila melanogaster)

Ghost homologue of C1D [nucleoplasm] (Dictyostelium discoideum)

C1D [nucleoplasm] (Bos taurus)

C1D [nucleoplasm] (Caenorhabditis elegans)

C1D [nucleoplasm] (Canis familiaris)

C1D [nucleoplasm] (Gallus gallus)

C1D [nucleoplasm] (Plasmodium falciparum)

C1D [nucleoplasm] (Rattus norvegicus)

C1D [nucleoplasm] (Schizosaccharomyces pombe)

C1D [nucleoplasm] (Sus scrofa)

LRP1 [nucleoplasm] (Saccharomyces cerevisiae)

c1d [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_001177192.1, NP_006324.1, NP_001177194.1, NP_775269.1

OpenTargets

ENSG00000197223

GeneCards

Q13901

HPA

ENSG00000197223-C1D

Ensembl

ENSP00000348107, ENST00000409302, ENSP00000386779, ENSG00000197223, ENST00000355848, ENSP00000386468, ENST00000410067

PRO

Q13901

Pharos - Targets

Q13901

Interactors (31)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q01780 EXOSC10	1	EXOSC10 [nucleoplasm] (R-HSA-6791547)	0.733	7
UniProt:Q9NQT4 EXOSC5	2	EXOSC5 [cytosol] (R-HSA-429889) EXOSC5 [nucleoplasm] (R-HSA-6791550)	0.725	5
UniProt:Q9Y371 SHLB1			0.718	6
UniProt:Q99547 MPHOSPH6	1	MPHOSPH6 [nucleoplasm] (R-HSA-6791553)	0.669	5
UniProt:Q13868 EXOSC2	2	EXOSC2 [nucleoplasm] (R-HSA-6791582) EXOSC2 [cytosol] (R-HSA-429999)	0.643	4
UniProt:Q9Y3B2 EXOSC1	2	EXOSC1 [nucleoplasm] (R-HSA-6791578) EXOSC1 [cytosol] (R-HSA-429841)	0.643	5
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:Q8N5A5-2 ZGPAT			0.556	3
UniProt:P51687 SUOX	1	SUOX [mitochondrial matrix] (R-HSA-1614570)	0.556	3
UniProt:P62826 RAN	2	RAN [nucleoplasm] (R-HSA-165528) RAN [cytosol] (R-HSA-165540)	0.556	3
UniProt:P13473-2 P134732			0.556	3
UniProt:O15499 GSC2			0.556	3
UniProt:O00291 HIP1	7	HIP1(1-719)insL-ALK(1059-1620) fusion [cytosol] (R-HSA-9711952) HIP1(1-1019)-ALK(1058-1620) [cytosol] (R-HSA-9711970) HIP1(1-963)-ALK(1058-1620) fusion [cytosol] (R-HSA-9711972) HIP1(1-719)insL-p-7Y-ALK(1059-1620) fusion [cytosol] (R-HSA-9711965) HIP1(1-1019)-p-7Y-ALK(1058-1620) [cytosol] (R-HSA-9711956) HIP1(1-963)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9711975) HIP1 [cytosol] (R-HSA-8868153)	0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	6
UniProt:P55212 CASP6	5	CASP6 (1-293) [cytosol] (R-HSA-6798132) CASP6(194-293) [nucleoplasm] (R-HSA-352246) CASP6(24-179) [nucleoplasm] (R-HSA-352247) CASP6(24-179) [cytosol] (R-HSA-350313) CASP6(194-293) [cytosol] (R-HSA-266128)	0.556	3
UniProt:Q5VWK5 IL23R	2	p-Y-IL23R [plasma membrane] (R-HSA-8950616) IL23R [plasma membrane] (R-HSA-447156)	0.556	3
UniProt:Q8IWA0 WDR75	1	WDR75 [nucleoplasm] (R-HSA-6790666)	0.527	2
UniProt:Q5RKV6 EXOSC6	2	EXOSC6 [nucleoplasm] (R-HSA-6791573) EXOSC6 [cytosol] (R-HSA-429921)	0.527	3
UniProt:Q15061 WDR43	1	WDR43 [nucleoplasm] (R-HSA-6790653)	0.527	2
UniProt:O60293 ZC3H1			0.527	2
UniProt:Q96B26 EXOSC8	2	EXOSC8 [nucleoplasm] (R-HSA-6791571) EXOSC8 [cytosol] (R-HSA-429912)	0.527	3
UniProt:Q6NZY4 ZCCHC8	1	ZCCHC8 [nucleoplasm] (R-HSA-8985573)	0.527	3
UniProt:Q9NPD3 EXOSC4	2	EXOSC4 [nucleoplasm] (R-HSA-6791503) EXOSC4 [cytosol] (R-HSA-430013)	0.527	3
UniProt:Q8TED0 UTP15	1	UTP15 [nucleoplasm] (R-HSA-6790678)	0.527	2
UniProt:Q06265 EXOSC9	2	EXOSC9 [nucleoplasm] (R-HSA-6791577) EXOSC9 [cytosol] (R-HSA-429984)	0.527	2
UniProt:Q9NQT5 EXOSC3	2	EXOSC3 [nucleoplasm] (R-HSA-6791572) EXOSC3 [cytosol] (R-HSA-430017)	0.527	3
UniProt:Q15024 EXOSC7	2	EXOSC7 [nucleoplasm] (R-HSA-6791543) EXOSC7 [cytosol] (R-HSA-430030)	0.527	3
UniProt:P42285 SKIV2L2	1	SKIV2L2 [nucleoplasm] (R-HSA-6791189)	0.527	3
UniProt:Q9Y580 RBM7	1	RBM7 [nucleoplasm] (R-HSA-8985564)	0.527	3
UniProt:Q9Y2L1 DIS3	2	DIS3 [nucleoplasm] (R-HSA-6791517) DIS3 [cytosol] (R-HSA-429935)	0.527	3
UniProt:Q9H8H0 NOL11	1	NOL11 [nucleoplasm] (R-HSA-6790684)	0.527	2

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