Reactome | EXOSC9 [nucleoplasm]

EXOSC9 [nucleoplasm]

Stable Identifier

R-HSA-6791577

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Exosome complex component RRP45, EXOS9_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q06265 EXOSC9

Gene Names

EXOSC9, PMSCL1

Chain

chain:1-439

Reference Genes

BioGPS Gene:5393 EXOSC9

COSMIC (genes):EXOSC9 EXOSC9

CTD Gene:5393 EXOSC9

dbSNP Gene:5393 EXOSC9

ENSEMBL:ENSG00000123737 EXOSC9

HGNC:9137 EXOSC9

KEGG:hsa:5393 EXOSC9

Monarch:5393 EXOSC9

NCBI Gene:5393 EXOSC9

OMIM:606180 EXOSC9

UCSC:Q06265 EXOSC9

Reference Transcript

Other Identifiers

11726371_a_at

11743004_x_at

11753011_a_at

16970231

205061_PM_s_at

205061_s_at

2741769

2741770

2741771

2741772

2741773

2741774

2741775

2741776

2741777

2741778

2741779

2741780

2741781

2741782

2741783

2741784

2741785

2741786

2741787

2741788

2741789

2741790

2741791

2741792

2741793

2741794

2741795

2741797

38838_at

5393

63921_at

8097128

A_14_P101091

A_14_P103714

A_14_P110705

A_14_P116450

A_23_P81121

GE81466

GO:0000175

GO:0000176

GO:0000177

GO:0000178

GO:0000228

GO:0000288

GO:0000467

GO:0000956

GO:0002376

GO:0003723

GO:0003824

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005730

GO:0005737

GO:0005829

GO:0006355

GO:0006364

GO:0006396

GO:0006399

GO:0006401

GO:0006402

GO:0006955

GO:0009057

GO:0016071

GO:0016073

GO:0016787

GO:0030307

GO:0034473

GO:0034475

GO:0034476

GO:0035925

GO:0043226

GO:0044248

GO:0045944

GO:0061629

GO:0070062

GO:0071028

GO:0071035

GO:0071038

GO:0101019

GO:0140098

GO:1902494

HMNXSV003047076

ILMN_1721713

ILMN_2312719

M58460_at

PH_hs_0005095

TC04000625.hg

g4826921_3p_a_at

Participates

as a component of

Exosome core complex [nucleoplasm] (Homo sapiens)

Other forms of this molecule

EXOSC9 [cytosol]

Inferred To

RRP45 [nucleoplasm] (Saccharomyces cerevisiae)

EXOSC9 [nucleoplasm] (Bos taurus)

EXOSC9 [nucleoplasm] (Canis familiaris)

EXOSC9 [nucleoplasm] (Dictyostelium discoideum)

EXOSC9 [nucleoplasm] (Gallus gallus)

EXOSC9 [nucleoplasm] (Plasmodium falciparum)

EXOSC9 [nucleoplasm] (Sus scrofa)

Exosc9 [nucleoplasm] (Mus musculus)

Exosc9 [nucleoplasm] (Rattus norvegicus)

Rrp45 [nucleoplasm] (Drosophila melanogaster)

exos-9 [nucleoplasm] (Caenorhabditis elegans)

rrp45 [nucleoplasm] (Schizosaccharomyces pombe)

Cross References

RefSeq

NP_001029366.1, NP_005024.2

ENSEMBL

ENST00000243498, ENST00000379663, ENSP00000368984, ENSP00000243498

OpenTargets

ENSG00000123737

HPA

ENSG00000123737-EXOSC9

PRO

Q06265

Pharos - Targets

Q06265

GlyGen

Q06265

Orphanet

EXOSC9

PDB

6D6R, 6H25, 6D6Q, 2NN6

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NQT4 EXOSC5	2	EXOSC5 [cytosol] (R-HSA-429889) EXOSC5 [nucleoplasm] (R-HSA-6791550)	0.643	5
UniProt:Q01780 EXOSC10	1	EXOSC10 [nucleoplasm] (R-HSA-6791547)	0.643	3
UniProt:P63279 UBE2I	9	monoSUMO1-K14-UBE2I [nucleoplasm] (R-HSA-4085358) UBE2I [nuclear envelope] (R-HSA-4655408) SUMO2-C93-UBE2I [cytosol] (R-HSA-4656944) SUMO3-C93-UBE2I [nucleoplasm] (R-HSA-3730629) UBE2I [nucleoplasm] (R-HSA-912481) SUMO1-C93-UBE2I [nucleoplasm] (R-HSA-3730617) SUMO2-C93-UBE2I [nucleoplasm] (R-HSA-3730619) SUMO1-C93-UBE2I [cytosol] (R-HSA-4656909) UBE2I [cytosol] (R-HSA-4655342)	0.553	2
UniProt:Q13901 C1D	1	C1D [nucleoplasm] (R-HSA-6791515)	0.527	2

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