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FTSJ2 [mitochondrial matrix]
Stable Identifier
R-HSA-6793061
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
fullName evidence="9"rRNA methyltransferase 2, mitochondrial ecNumber evidence="13"2.1.1.-/ecNumber, MRM2_HUMAN
Locations in the PathwayBrowser for interactor UniProt:P62079 TSPAN5
Expand all
Metabolism of RNA (Homo sapiens)
rRNA processing (Homo sapiens)
rRNA processing in the mitochondrion (Homo sapiens)
rRNA modification in the mitochondrion (Homo sapiens)
MRM2 (FTSJ2) methylates uridine-1369 of 16S rRNA yielding 2'-O-methyluridine (Homo sapiens)
FTSJ2 [mitochondrial matrix] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UI43 MRM2
Gene Names
MRM2, FJH1, FTSJ2
Chain
transit peptide:1-18, chain:19-246
Reference Genes
BioGPS Gene:29960 MRM2
COSMIC (genes):MRM2 MRM2
CTD Gene:29960 MRM2
dbSNP Gene:29960 MRM2
ENSEMBL:ENSG00000122687 MRM2
ENSEMBL_homo_sapiens_GENE:ENSG00000122687.19 MRM2
HGNC:16352 MRM2
KEGG Gene (Homo sapiens):29960 MRM2
Monarch:29960 MRM2
NCBI Gene:29960 MRM2
OMIM:606906 MRM2
Reference Transcript
RefSeq:NM_013393.1 MRM2
Other Identifiers
11723717_a_at
17054532
218356_PM_at
218356_at
222130_PM_s_at
222130_s_at
29960
3035683
3035684
3035685
3035686
3035689
3035690
3035693
63883_at
73350_at
8137826
A_24_P363477
GE62059
GO:0000451
GO:0001510
GO:0003824
GO:0005634
GO:0005730
GO:0005739
GO:0005759
GO:0006364
GO:0008168
GO:0008173
GO:0008650
GO:0016740
GO:0031167
GO:0032259
GO:0042254
GO:0043226
GO:0065003
GO:0140098
GO:1902775
HMNXSV003018153
Hs.279877.1.S1_3p_a_at
ILMN_1815933
PH_hs_0014417
TC07001095.hg
g7019376_3p_at
Cross References
RefSeq
NP_037525.1
OpenTargets
ENSG00000122687
GeneCards
Q9UI43
HPA
ENSG00000122687-MRM2
Ensembl
ENSG00000122687
,
ENST00000242257
,
ENSP00000392343
,
ENSP00000242257
,
ENST00000440306
PRO
Q9UI43
Pharos - Targets
Q9UI43
HMDB Protein
HMDBP09031
PDB
7O9K
,
7O9M
,
2NYU
,
7ODS
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8WVZ9 KBTBD7
1
KBTBD7 [cytosol]
(R-HSA-5658415)
0.643
7
UniProt:P10809 HSPD1
6
HSPD1 [mitochondrial matrix]
(R-HSA-1299448)
HSPD1(1-573) [cytosol]
(R-HSA-1267989)
HSPD1(1-573) [mitochondrial intermembrane space]
(R-HSA-1267963)
HSPD1 [mitochondrial inner membrane]
(R-HSA-1299455)
HSPD1(1-573) [mitochondrial inner membrane]
(R-HSA-1299442)
HSPD1(1-26) [mitochondrial matrix]
(R-HSA-8986171)
0.527
4
UniProt:P62079 TSPAN5
2
TSPAN5 [plasma membrane]
(R-HSA-9010031)
TSPAN5 [endoplasmic reticulum lumen]
(R-HSA-9010081)
0.527
2
UniProt:Q9H8J5 MANS1
0.527
2
UniProt:P08218 CEL2B
0.527
2
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