Expression of GATA3

Stable Identifier
R-HSA-6793975
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Expression of GATA3
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Phosphorylated Signal transducer and activator of transcription 6 (STAT6) dimers translocate to the nucleus and activate the transcription of several genes including the nuclear protein Trans-acting T-cell-specific transcription factor GATA-3 (Takeda et al. 1994, Park et al. 1998).

Literature References
PubMed ID Title Journal Year
8602263 Essential role of Stat6 in IL-4 signalling

Yoshida, N, Shi, W, Kishimoto, T, Nakanishi, K, Matsumoto, M, Akira, S, Kashiwamura, S, Tanaka, T, Minami, M, Takeda, K

Nature 1996
9736340 Interferon-gamma-induced factor binding to the interleukin-4-responsive element of CD23b promoter in human tonsillar mononuclear cells: role in transient up-regulation of the interleukin-4-induced CD23b mRNA

So, EY, Lee, CE, Park, HJ

Mol. Immunol. 1998
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
p-Y641-STAT6 dimer [nucleoplasm] (Homo sapiens)
Authored
Jupe, S  (2015-07-01)
Reviewed
Leibovich, SJ  (2016-09-02)
Created
Jupe, S  (2015-09-04)
Cite Us!