Reactome | APBA2 [cytosol]

APBA2 [cytosol]

Stable Identifier

R-HSA-6794245

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Amyloid beta A4 precursor protein-binding family A member 2, APBA2_HUMAN, MINT2

Locations in the PathwayBrowser

Expand all

Neuronal System (Homo sapiens)

- Protein-protein interactions at synapses (Homo sapiens)
  - Neurexins and neuroligins (Homo sapiens)
    - NRXNs binds MUNC18 (Homo sapiens)
      - NRXNs:STX1A:MUNC18:MINT1,2,(3) [plasma membrane] (Homo sapiens)
        
        STX1A:MUNC18:MINT1,2,(3) [plasma membrane] (Homo sapiens)
        
        MINT1,2,(3) [cytosol] (Homo sapiens)
        
        APBA2 [cytosol] (Homo sapiens)
      - STX1A:MUNC18:MINT1,2,(3) [plasma membrane] (Homo sapiens)
        
        MINT1,2,(3) [cytosol] (Homo sapiens)
        
        APBA2 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q99767 APBA2

Gene Names

APBA2, MINT2, X11L

Chain

chain:1-749

Reference Genes

BioGPS Gene:321 APBA2

COSMIC (genes):APBA2 APBA2

CTD Gene:321 APBA2

dbSNP Gene:321 APBA2

ENSEMBL:ENSG00000034053 APBA2

ENSEMBL:ENSG00000034053.15 APBA2

ENSEMBL:ENSG00000276495.4 APBA2

HGNC:579 APBA2

KEGG Gene (Homo sapiens):321 APBA2

Monarch:321 APBA2

NCBI Gene:321 APBA2

OMIM:602712 APBA2

UCSC:Q99767 APBA2

Reference Transcript

Other Identifiers

11727629_at

11727630_s_at

11727631_s_at

16798624

209870_PM_s_at

209870_s_at

209871_PM_s_at

209871_s_at

321

3585907

3585908

3585909

3585929

3585939

3585940

3585941

3585950

3585951

3585958

3585961

3585962

3585966

3585972

3585974

3585978

3585979

3585981

3585983

3585984

3585985

39590_at

7982187

A_14_P121452

A_23_P146849

A_23_P158231

GE54404

GO:0001540

GO:0001701

GO:0005515

GO:0005737

GO:0005886

GO:0007268

GO:0007399

GO:0007626

GO:0010468

GO:0015031

GO:0023052

GO:0035264

GO:0042802

GO:0043197

GO:0048856

GO:0098685

GO:0098793

GO:0099171

HMNXSV003009926

Hs.26468.0.A1_3p_a_at

ILMN_1723626

PH_hs_0002333

TC15000153.hg

U79255_at

g3953612_3p_a_at

Participates

as a candidate of

MINT1,2,(3) [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_016877603.1, XP_016877605.1, XP_016877591.1, XP_011519794.1, XP_016877598.1, XP_016877600.1, XP_016877596.1, XP_016877594.1, XP_016877602.1, XP_011519792.1, XP_016877604.1, XP_016877599.1, XP_016877592.1, NP_001123886.1, XP_011519793.1, XP_016877590.1, NP_005494.2, XP_011519790.1, XP_016877597.1, XP_016877595.1, XP_011519791.1, XP_016877606.1, XP_016877593.1, XP_016877601.1

OpenTargets

ENSG00000034053

GeneCards

Q99767

HPA

ENSG00000034053-APBA2

Ensembl

ENSP00000453144, ENST00000631894, ENST00000683413, ENST00000411764, ENSP00000480384, ENST00000558330, ENST00000612449, ENSP00000488107, ENSP00000507394, ENST00000561069, ENSP00000483174, ENSG00000034053, ENST00000620457, ENSP00000409312, ENSG00000276495, ENSP00000454171, ENST00000558402, ENSP00000453293, ENST00000558259, ENSP00000452722

PRO

Q99767

Pharos - Targets

Q99767

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P05067 APP	20	APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [extracellular region] (R-HSA-49335) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-687) [extracellular region] (R-HSA-9010033) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(18-770) [endosome lumen] (R-HSA-5229077) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP [endoplasmic reticulum lumen] (R-HSA-8956696) APP(672-711) [extracellular region] (R-HSA-976740) APP(672-711) [cytosol] (R-HSA-877188) APP(672-713) [extracellular region] (R-HSA-879340)	0.592	2

Cite Us!