Reactome | BEGAIN [cytosol]

BEGAIN [cytosol]

Stable Identifier

R-HSA-6794250

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Brain-enriched guanylate kinase-associated protein, BEGIN_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9BUH8 BEGAIN

Gene Names

BEGAIN, KIAA1446

Chain

chain:1-593

Reference Genes

BioGPS Gene:57596 BEGAIN

COSMIC (genes):BEGAIN BEGAIN

CTD Gene:57596 BEGAIN

dbSNP Gene:57596 BEGAIN

ENSEMBL:ENSG00000183092 BEGAIN

HGNC:24163 BEGAIN

KEGG:hsa:57596 BEGAIN

Monarch:57596 BEGAIN

NCBI Gene:57596 BEGAIN

OMIM:618597 BEGAIN

UCSC:Q9BUH8 BEGAIN

Reference Transcript

Other Identifiers

11754479_a_at

16796727

220795_PM_s_at

220795_s_at

3579611

3579612

3579613

3579614

3579620

3579621

3579622

3579623

3579624

3579625

3579626

3579627

3579628

3579629

3579630

3579637

3579638

3579639

3579640

3579642

3579643

3579644

3579648

57596

70950_at

7981309

A_23_P72127

A_33_P3321205

GE689318

GE87136

GO:0003824

GO:0005515

GO:0005737

GO:0016020

GO:0016301

GO:0016740

GO:0045202

HMNXSV003032492

ILMN_1668924

g13124764_3p_a_at

Participates

as a component of

NMDA receptor complex:PSD-95:BEGAIN [plasma membrane] (Homo sapiens)

as an input of

BEGAIN binds DLG2,DLG3,DLG4 (Homo sapiens)

Cross References

OpenTargets

ENSG00000183092

ENSEMBL

ENST00000557378, ENSP00000451397, ENSP00000347301, ENST00000556188, ENST00000355173, ENSP00000450722, ENSP00000452157, ENST00000553553

HPA

ENSG00000183092-BEGAIN

PRO

Q9BUH8

Pharos - Targets

Q9BUH8

Interactors (35)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q6NX45 ZNF774	1	ZNF774 [nucleoplasm] (R-HSA-3110232)	0.718	6
UniProt:Q96L14 C170L			0.669	3
UniProt:Q8TAU3 ZNF417	1	ZNF417 [nucleoplasm] (R-HSA-1247539)	0.666	6
UniProt:Q9H0I2 ENKD1			0.666	4
UniProt:Q8BFT2	1	Haus4 [cytosol] (R-MMU-8855202)	0.564	2
UniProt:Q96BZ8 LENG1	1	LENG1 [nucleoplasm] (R-HSA-9769590)	0.556	3
UniProt:Q99633 PRPF18	1	PRPF18 [nucleoplasm] (R-HSA-5688093)	0.556	3
UniProt:Q96CV9 OPTN	6	p-S177,S473,S513-OPTN [cytosol] (R-HSA-9687840) OPTN [cytosol] (R-HSA-9687907) p-S177-OPTN [cytosol] (R-HSA-2562525) p-S177-OPTN [nucleoplasm] (R-HSA-2562595) OPTN [Golgi membrane] (R-HSA-2161111) OPTN [recycling endosome membrane] (R-HSA-8854141)	0.556	3
UniProt:Q8N5M1 ATPF2			0.556	5
UniProt:Q9Y2P0 ZN835			0.556	3
UniProt:Q86YV0 RASAL3	1	RASAL3 [cytosol] (R-HSA-5658226)	0.556	3
UniProt:Q9P2F9 ZN319			0.556	5
UniProt:Q9BVG8-5 KIFC3			0.556	3
UniProt:Q5T619 ZN648			0.556	5
UniProt:Q7Z3I7 ZN572			0.556	5
UniProt:Q96EG3 ZN837			0.556	3
UniProt:Q9BUZ4 TRAF4			0.556	3
UniProt:O60941-5 DTNB			0.556	3
UniProt:Q96IK5 GMCL1			0.556	5
UniProt:Q9BT92 TCHP			0.556	3
UniProt:Q96SQ5 ZNF587	1	ZNF587 [nucleoplasm] (R-HSA-2127565)	0.556	3
UniProt:Q9UJX2 CDC23	2	CDC23 [cytosol] (R-HSA-174137) CDC23 [nucleoplasm] (R-HSA-174228)	0.556	3
UniProt:Q96NT3-2 GUCD1			0.556	3
UniProt:P55040 GEM	1	GEM [plasma membrane] (R-HSA-9769962)	0.556	5
UniProt:Q86YD7 F90A1			0.556	3
UniProt:Q8IYX7 SAXO1			0.556	3
UniProt:Q8N8X9 MB213			0.556	3
UniProt:P0CG20 PRR35			0.556	3
UniProt:P29972 AQP1	1	AQP1 [plasma membrane] (R-HSA-431700)	0.556	3
UniProt:P56524-2 HDAC4			0.556	3
UniProt:P18075 BMP7	2	BMP7(30-292) [extracellular region] (R-HSA-206223) BMP7 [extracellular region] (R-HSA-206257)	0.556	3
UniProt:P26196 DDX6	1	DDX6 [cytosol] (R-HSA-430032)	0.556	3
UniProt:Q3B820 F161A			0.556	3
UniProt:P28749 RBL1	2	RBL1 [nucleoplasm] (R-HSA-389104) p-T369,S640,S964,S975-RBL1 [nucleoplasm] (R-HSA-1226085)	0.508	2
UniProt:Q5VTD9 GFI1B			0.488	2

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