Expression of HMOX1

Stable Identifier
R-HSA-6797268
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, endoplasmic reticulum membrane
ReviewStatus
5/5
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Expression of HMOX1
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In human peripheral blood monocytes Interleukin-4 (IL4) and IL13 significantly upregulate the levels of proteins involved in inflammatory resolution, including the ER membrane protein 15-lipoxygenase (ALOX15) (Chaitidis et al. 2005).

Literature References
PubMed ID Title Journal Year
15869882 Gene expression alterations of human peripheral blood monocytes induced by medium-term treatment with the TH2-cytokines interleukin-4 and -13

Chaitidis, P, Bermudez-Fajardo, A, Kuban, RJ, O'Donnell, V, Kühn, H, Ungethuem, U

Cytokine 2005
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
IL4, IL13 [extracellular region] (Homo sapiens)
Authored
Jupe, S  (2015-07-01)
Reviewed
Leibovich, SJ  (2016-09-02)
Created
Jupe, S  (2015-09-07)
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