Reactome | BNIP3L [mitochondrial outer membrane]

BNIP3L [mitochondrial outer membrane]

Stable Identifier

R-HSA-6798001

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial outer membrane

Synonyms

BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like, NIX, NIP3-like protein X

Locations in the PathwayBrowser for interactor UniProt:P17152 TMEM11

Expand all

External Reference Information

External Reference

UniProt:O60238 BNIP3L

Gene Names

BNIP3L, BNIP3A, BNIP3H, NIX

Chain

chain:1-219

Reference Genes

BioGPS Gene:665 BNIP3L

COSMIC (genes):BNIP3L BNIP3L

CTD Gene:665 BNIP3L

dbSNP Gene:665 BNIP3L

ENSEMBL:ENSG00000104765 BNIP3L

ENSEMBL:ENSG00000104765.16 BNIP3L

HGNC:1085 BNIP3L

KEGG Gene (Homo sapiens):665 BNIP3L

Monarch:665 BNIP3L

NCBI Gene:665 BNIP3L

OMIM:605368 BNIP3L

UCSC:O60238 BNIP3L

Reference Transcript

Other Identifiers

11717008_a_at

11745828_x_at

11746802_x_at

11748909_a_at

11753422_a_at

11757303_s_at

17067170

221478_PM_at

221478_at

221479_PM_s_at

221479_s_at

3091001

3091002

3091003

3091004

3091011

3091012

3091013

3091014

3091015

3091021

3091030

3091031

3091035

3091036

3091037

3091038

3091039

3091040

3091041

3091042

39436_at

45770_at

52583_s_at

665

8145454

A_23_P134925

A_33_P3396951

GE505461

GE56569

GO:0005515

GO:0005521

GO:0005634

GO:0005635

GO:0005654

GO:0005739

GO:0005740

GO:0005741

GO:0005783

GO:0006886

GO:0006914

GO:0006915

GO:0007005

GO:0012501

GO:0016020

GO:0016239

GO:0016607

GO:0019222

GO:0023052

GO:0030163

GO:0035694

GO:0042802

GO:0042803

GO:0043065

GO:0043066

GO:0043067

GO:0043069

GO:0043226

GO:0051607

GO:0061024

GO:0071456

GO:0097345

GO:0098542

GO:1903146

GO:1903214

HMNXSV003053142

Hs.132955.0.S2_3p_at

ILMN_1718961

ILMN_2045419

TC08000200.hg

g12001981_3p_a_at

Participates

as an output of

TP53 stimulates BNIP3L expression (Homo sapiens)

as a component of

STEAP3:BNIP3L [mitochondrial outer membrane] (Homo sapiens)

as an input of

STEAP3 binds BNIP3L (Homo sapiens)

Inferred To

bnip3l [mitochondrial outer membrane] (Xenopus tropicalis)

bnip3l2 [mitochondrial outer membrane] (Danio rerio)

BNIP3L [mitochondrial outer membrane] (Bos taurus)

BNIP3L [mitochondrial outer membrane] (Canis familiaris)

BNIP3L [mitochondrial outer membrane] (Gallus gallus)

BNIP3L [mitochondrial outer membrane] (Sus scrofa)

Bnip3l [mitochondrial outer membrane] (Mus musculus)

Bnip3l [mitochondrial outer membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_004322.1, NP_001317420.1

OpenTargets

ENSG00000104765

HPA

ENSG00000104765-BNIP3L

GeneCards

O60238

Ensembl

ENST00000380629, ENSP00000429698, ENST00000523515, ENSP00000428597, ENST00000520409, ENSP00000370003, ENST00000518611, ENSG00000104765, ENSP00000429851

PRO

O60238

Pharos - Targets

O60238

Interactors (21)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q12983 BNIP3			0.962	22
UniProt:O60238 BNIP3L	1	BNIP3L [mitochondrial outer membrane] (R-HSA-6798001)	0.863	11
UniProt:P17152 TMEM11	1	TMEM11 [mitochondrial inner membrane] (R-HSA-8949578)	0.841	9
UniProt:Q9NRQ5 SMCO4			0.781	7
UniProt:P38182	12	ATG8 [cytosol] (R-SCE-5205676) ATG8 [cytosol] (R-SCE-5205651) ATG8 [cytosol] (R-SCE-975521) ATG8 [cytosol] (R-SCE-5679223) ATG8 [cytosol] (R-SCE-5682696) ATG8 [cytosol] (R-SCE-5682674) ATG8 [cytosol] (R-SCE-5682653) ATG8 [cytosol] (R-SCE-5682681) ATG8 [autophagosome membrane] (R-SCE-5683634) ATG8 [autophagosome membrane] (R-SCE-5683638) ATG8 [autophagosome membrane] (R-SCE-5683640) ATG8 [autophagosome membrane] (R-SCE-5683641)	0.666	4
UniProt:Q9BXN2 CLEC7A	2	CLEC7A [plasma membrane] (R-HSA-2130683) p-Y15-CLEC7A [plasma membrane] (R-HSA-5607641)	0.666	6
UniProt:Q5T700 LRAD1			0.666	4
UniProt:P03247 E1BS			0.646	7
UniProt:A0PK00 T120B			0.556	3
UniProt:Q9BXN2-6 CLEC7A			0.556	3
UniProt:Q13021 MALL			0.556	3
UniProt:P60520 GABARAPL2	3	GABARAPL2 [autophagosome membrane] (R-HSA-5683633) GABARAPL2(1-117) [cytosol] (R-HSA-5682641) GABARAPL2 [cytosol] (R-HSA-5671758)	0.556	3
UniProt:Q9NRS4 TMPS4			0.556	3
UniProt:Q15848 ADIPOQ	1	ADIPOQ [extracellular region] (R-HSA-1183052)	0.556	3
UniProt:A0A663DJA2 ORF10			0.556	4
UniProt:Q969F0 FATE1			0.556	3
UniProt:O43169 CYB5B	1	CYB5B [mitochondrial outer membrane] (R-HSA-8943390)	0.556	3
UniProt:Q9H0R8 GABARAPL1	3	GABARAPL1 [autophagosome membrane] (R-HSA-5683637) GABARAPL1(1-117) [cytosol] (R-HSA-5682659) GABARAPL1 [cytosol] (R-HSA-5671757)	0.556	3
UniProt:Q9H2S6-2 TNMD			0.556	3
UniProt:P22736-1 NR4A1			0.544	4
UniProt:Q9NQ11 ATP13A2	1	ATP13A2 [lysosomal lumen] (R-HSA-939762)	0.508	2

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