Reactome | RPS15 [nucleoplasm]

RPS15 [nucleoplasm]

Stable Identifier

R-HSA-6798706

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

40S small ribosomal protein 15, P11174, 40S ribosomal protein S15, RIG protein

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P62841 RPS15

Gene Names

RPS15, RIG

Chain

initiator methionine:, chain:2-145

Reference Genes

BioGPS Gene:6209 RPS15

COSMIC (genes):RPS15 RPS15

CTD Gene:6209 RPS15

dbSNP Gene:6209 RPS15

ENSEMBL:ENSG00000115268 RPS15

HGNC:10388 RPS15

KEGG:hsa:6209 RPS15

Monarch:6209 RPS15

NCBI Gene:6209 RPS15

OMIM:180535 RPS15

UCSC:P62841 RPS15

Reference Transcript

RefSeq:NM_001018.4 RPS15

Other Identifiers

11757375_x_at

1563014_PM_at

1563014_at

16856581

200819_PM_s_at

200819_s_at

2352562

2586800

2586801

2586802

3815730

3815731

3815732

3815733

3815734

3815735

3815736

3815737

3815738

3815739

3815740

3815741

3815742

3815743

3815744

3815745

39916_r_at

6209

8024299

8024304

A_14_P137259

A_23_P209152

A_24_P225010

GE542219

GO:0000028

GO:0000056

GO:0001649

GO:0002181

GO:0003677

GO:0003723

GO:0003735

GO:0005198

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005840

GO:0005925

GO:0006364

GO:0006412

GO:0006913

GO:0015935

GO:0016020

GO:0022626

GO:0022627

GO:0030154

GO:0042274

GO:0043226

GO:0045202

GO:0048856

GO:0065003

GO:0097371

GO:0097421

GO:0098772

GO:1901798

GO:1990904

GO:1990948

HMNXSV003018725

Hs2.333160.1.S1_3p_at

ILMN_2219131

ILMN_2219134

M32405_at

TC19000039.hg

g4506686_3p_a_at

Participates

as a component of

18SE pre-40S particle [nucleoplasm] (Homo sapiens)

Other forms of this molecule

RPS15 [cytosol]

Inferred To

rps-15 [nucleoplasm] (Caenorhabditis elegans)

Ghost homologue of RPS15 [nucleoplasm] (Xenopus tropicalis)

rps15 [nucleoplasm] (Danio rerio)

rps15 [nucleoplasm] (Dictyostelium discoideum)

RPS15 [nucleoplasm] (Bos taurus)

RPS15 [nucleoplasm] (Canis familiaris)

RPS15 [nucleoplasm] (Gallus gallus)

RPS15 [nucleoplasm] (Plasmodium falciparum)

RPS15 [nucleoplasm] (Saccharomyces cerevisiae)

RPS15 [nucleoplasm] (Sus scrofa)

rps1501 [nucleoplasm] (Schizosaccharomyces pombe)

RpS15 [nucleoplasm] (Drosophila melanogaster)

Rps15 [nucleoplasm] (Mus musculus)

Rps15 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_001009.1

OpenTargets

ENSG00000115268

ENSEMBL

ENST00000592588, ENSP00000467466

HPA

ENSG00000115268-RPS15

PRO

P62841

Pharos - Targets

P62841

Orphanet

RPS15

GlyGen

P62841

PDB

7QP7, 6Z6M, 6Z6L, 6G53, 8PPL, 6G4W, 7WTT, 5VYC, 6G18, 6ZN5, 6OLE, 8G60, 6ZMI, 8JDK, 8JDM, 6ZOJ, 6ZMO, 6ZMW, 6ZV6, 4V6X, 6ZVH, 8IFD, 6ZXG, 6ZXF, 7TQL, 8PPK, 6ZVJ, 8JDJ, 6OLZ, 4UG0, 8IFE, 8G61, 8G6J, 5LKS, 8OZ0, 6FEC, 7A09, 6IP6, 6ZXE, 6G5I, 6ZME, 6G5H, 6ZXD, 5FLX, 6ZP4, 6YBS, 6ZOL, 7WU0, 7QP6, 6Y0G, 6OM0, 8Y0X, 7WTW, 7WTU, 6OLI, 8T4S, 5A2Q, 6OLG, 6G4S, 8Y0W, 6G51, 6ZMT, 7WTV, 6Z6N, 7WTZ, 7WTX, 7XNY, 5AJ0, 5OA3, 8GLP, 6ZUO, 8JDL, 7XNX, 6OLF, 8G5Y, 6OM7, 7K5I, 6ZXH, 7R4X, 6ZLW, 6XA1, 6ZM7, 6IP5, 6Y2L, 5T2C, 6Y57, 6QZP, 6IP8, 6ZON

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.783	9
UniProt:P63244 RACK1	1	GNB2L1 [cytosol] (R-HSA-5626956)	0.715	4
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.643	11
UniProt:P62937 PPIA	5	PPIA [extracellular exosome] (R-HSA-6801538) PPIA [ficolin-1-rich granule lumen] (R-HSA-6801391) PPIA [extracellular region] (R-HSA-173646) PPIA [secretory granule lumen] (R-HSA-6801400) PPIA [cytosol] (R-HSA-173123)	0.556	3
UniProt:P15880 RPS2	3	RPS2 [cytosol] (R-HSA-72347) Me2aR-RPS2 [cytosol] (R-HSA-8879138) RPS2 [nucleoplasm] (R-HSA-6790655)	0.527	3
UniProt:P16104 H2AFX	7	H2AFX [nucleoplasm] (R-HSA-56151) p-Y143-H2AFX [nucleoplasm] (R-HSA-5683942) p-S140,Y143-H2AFX [nucleoplasm] (R-HSA-5683953) p-S140-H2AFX [nucleoplasm] (R-HSA-75170) K63PolyUb-K14,K16,p-S140-H2AFX [nucleoplasm] (R-HSA-5682847) H2AFX [extracellular region] (R-HSA-977583) Me2sR4-H2AFX [nucleoplasm] (R-HSA-5218317)	0.527	3
UniProt:P62249 RPS16	2	RPS16 [cytosol] (R-HSA-72337) RPS16 [nucleoplasm] (R-HSA-6791196)	0.527	2
UniProt:P0DTC9 N	13	SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729340) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9729341) ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729275) p-11S,2T-metR95,177-N [cytosol] (R-COV-9729308) p-11S,2T-N [cytosol] (R-COV-9729264) p-8S,2T-N [cytosol] (R-COV-9729277) p-8S-N [cytosol] (R-COV-9729335) p-S188,206-N [cytosol] (R-COV-9729324) N [cytosol] (R-COV-9694300) SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol] (R-COV-9756489) N [plasma membrane] (R-COV-9694356) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus] (R-COV-9729339) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane] (R-COV-9729325)	0.527	3
UniProt:Q00839 HNRNPU	1	HNRNPU [nucleoplasm] (R-HSA-71953)	0.527	2
UniProt:Q9H9Z2 LIN28A	1	LIN28A [cytosol] (R-HSA-500391)	0.527	3

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