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ARG1 [azurophil granule lumen]
Stable Identifier
R-HSA-6798764
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
azurophil granule lumen
Synonyms
arginase 1, liver-type arginase, Arginase 1
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of azurophil granule lumen proteins (Homo sapiens)
Azurophil granule lumen proteins [azurophil granule lumen] (Homo sapiens)
ARG1 [azurophil granule lumen] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
8849731
Structure of a unique binuclear manganese cluster in arginase.
Christianson, DW
,
Scolnick, LR
,
Ash, DE
,
Kanyo, ZF
Nature
1996
External Reference Information
External Reference
UniProt:P05089 ARG1
Gene Names
ARG1
Chain
chain:1-322
Reference Genes
BioGPS Gene:383 ARG1
COSMIC (genes):ARG1 ARG1
CTD Gene:383 ARG1
dbSNP Gene:383 ARG1
ENSEMBL:ENSG00000118520 ARG1
HGNC:663 ARG1
KEGG:hsa:383 ARG1
Monarch:383 ARG1
NCBI Gene:383 ARG1
OMIM:608313 ARG1
UCSC:P05089 ARG1
Reference Transcript
RefSeq:NM_000045.3 ARG1
RefSeq:NM_001244438.1 ARG1
Other Identifiers
11754669_a_at
17012582
1962_at
206177_PM_s_at
206177_s_at
2925842
2925843
2925844
2925846
2925848
2925849
2925850
2925851
2925853
2925854
2925856
2925857
2925858
2925859
2925860
2925861
383
78251_at
8122058
A_14_P130107
A_23_P111321
A_33_P3319967
A_33_P3352382
GE59705
GO:0000050
GO:0002250
GO:0002376
GO:0003824
GO:0004053
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005737
GO:0005829
GO:0006520
GO:0006525
GO:0006527
GO:0016787
GO:0016813
GO:0019547
GO:0030145
GO:0035578
GO:0035580
GO:0042130
GO:0042832
GO:0043226
GO:0045087
GO:0046007
GO:0046872
GO:0060336
GO:0070965
GO:0071941
GO:0098542
GO:2000552
HMNXSV003024020
ILMN_1812281
PH_hs_0025817
TC06000983.hg
X12662_rna1_at
g10947138_3p_s_at
Participates
as a member of
Azurophil granule lumen proteins [azurophil granule lumen] (Homo sapiens)
Other forms of this molecule
ARG1 [specific granule lumen]
ARG1 [extracellular region]
ARG1 [cytosol]
Inferred To
ARG1 [azurophil granule lumen]
(Bos taurus)
ARG1 [azurophil granule lumen]
(Canis familiaris)
ARG1 [azurophil granule lumen]
(Dictyostelium discoideum)
ARG1 [azurophil granule lumen]
(Drosophila melanogaster)
ARG1 [azurophil granule lumen]
(Mus musculus)
ARG1 [azurophil granule lumen]
(Plasmodium falciparum)
ARG1 [azurophil granule lumen]
(Rattus norvegicus)
ARG1 [azurophil granule lumen]
(Saccharomyces cerevisiae)
ARG1 [azurophil granule lumen]
(Schizosaccharomyces pombe)
ARG1 [azurophil granule lumen]
(Sus scrofa)
ARG1 [azurophil granule lumen]
(Xenopus tropicalis)
argn-1 [azurophil granule lumen]
(Caenorhabditis elegans)
Cross References
Guide to Pharmacology - Targets
1244
OpenTargets
ENSG00000118520
ENSEMBL
ENSP00000357066
,
ENST00000368087
,
ENSP00000349446
,
ENST00000356962
ZINC - Substances
ARGI1_HUMAN
ZINC target
P05089
PRO
P05089
GlyGen
P05089
PDB
3SKK
,
3KV2
,
4HXQ
,
7K4G
,
3MJL
,
7K4J
,
7K4H
,
4GSV
,
4FCK
,
3THH
,
7KLM
,
4HWW
,
8AUP
,
2PHO
,
7LEY
,
7LF1
,
1WVA
,
3LP4
,
4GWD
,
2PHA
,
3E6K
,
6V7E
,
3MFV
,
6V7C
,
3E6V
,
3MFW
,
3TH7
,
4GSM
,
2AEB
,
3DJ8
,
8E5M
,
7K4I
,
7K4K
,
8E5N
,
3THE
,
3TF3
,
7KLL
,
4GWC
,
6QAF
,
7KLK
,
4FCI
,
7LEX
,
7LEZ
,
3GN0
,
7LF2
,
1WVB
,
4IE1
,
2ZAV
,
6Q9P
,
6V7F
,
3LP7
,
3SJT
,
6V7D
,
3THJ
,
6Q92
,
4GSZ
,
2PLL
,
3GMZ
,
7LF0
,
3F80
HPA
ENSG00000118520-ARG1
Pharos - Targets
P05089
Orphanet
ARG1
ZINC - Predictions - Purchasable
ARGI1_HUMAN
HMDB Protein
HMDBP00298
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P03372 ESR1
10
ESR1 [cytosol]
(R-HSA-9020968)
ESR1 [nucleoplasm]
(R-HSA-446168)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
p-S167-ESR1 [cytosol]
(R-HSA-9841254)
p-S167-ESR1 [nucleoplasm]
(R-HSA-9841867)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
0.527
2
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