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FAF2 [azurophil granule lumen]
Stable Identifier
R-HSA-6799138
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
azurophil granule lumen
Synonyms
FAS-associated factor 2, FAF2_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of azurophil granule lumen proteins (Homo sapiens)
Azurophil granule lumen proteins [azurophil granule lumen] (Homo sapiens)
FAF2 [azurophil granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96CS3 FAF2
Gene Names
FAF2, ETEA, KIAA0887, UBXD8, UBXN3B
Chain
initiator methionine:1, chain:2-445
Reference Genes
BioGPS Gene:23197 FAF2
COSMIC (genes):FAF2 FAF2
CTD Gene:23197 FAF2
dbSNP Gene:23197 FAF2
ENSEMBL:ENSG00000113194 FAF2
HGNC:24666 FAF2
KEGG Gene (Homo sapiens):23197 FAF2
Monarch:23197 FAF2
NCBI Gene:23197 FAF2
OMIM:616935 FAF2
UCSC:Q96CS3 FAF2
Reference Transcript
RefSeq:NM_014613.2 FAF2
Other Identifiers
0000580433
11716000_a_at
11716001_at
11716002_at
11716003_a_at
11716004_at
11753411_a_at
16992814
212106_at
212108_at
23197
2842575
2842576
2842585
2842586
2842587
2842589
2842594
2842597
2842598
2842601
2842605
2842606
2842610
2842611
2842612
2842613
2842614
37030_at
8110169
A_14_P119601
A_23_P156109
A_24_P294719
GE53562
GO:0002376
GO:0003674
GO:0005515
GO:0005575
GO:0005576
GO:0005622
GO:0005737
GO:0005764
GO:0005773
GO:0005783
GO:0005811
GO:0006810
GO:0006950
GO:0006986
GO:0008150
GO:0009056
GO:0015031
GO:0016192
GO:0019899
GO:0030234
GO:0030433
GO:0030970
GO:0031410
GO:0031625
GO:0032182
GO:0032991
GO:0034098
GO:0034389
GO:0035473
GO:0035578
GO:0043086
GO:0043130
GO:0043161
GO:0043226
GO:0043312
GO:0055102
HMNXSV003046384
Hs.76591.0.S1_3p_at
Hs.76591.0.S2_3p_at
ILMN_1670472
PH_hs_0004422
TC05001000.hg
Participates
as a member of
Azurophil granule lumen proteins [azurophil granule lumen] (Homo sapiens)
Other forms of this molecule
FAF2 [cytosol]
FAF2 [extracellular region]
Inferred To
ucp10 [azurophil granule lumen]
(Schizosaccharomyces pombe)
Faf2 [azurophil granule lumen]
(Drosophila melanogaster)
Faf2 [azurophil granule lumen]
(Mus musculus)
Faf2 [azurophil granule lumen]
(Rattus norvegicus)
FAF2 [azurophil granule lumen]
(Caenorhabditis elegans)
FAF2 [azurophil granule lumen]
(Canis familiaris)
FAF2 [azurophil granule lumen]
(Dictyostelium discoideum)
FAF2 [azurophil granule lumen]
(Gallus gallus)
FAF2 [azurophil granule lumen]
(Plasmodium falciparum)
FAF2 [azurophil granule lumen]
(Sus scrofa)
UBX2 [azurophil granule lumen]
(Saccharomyces cerevisiae)
UBX3 [azurophil granule lumen]
(Saccharomyces cerevisiae)
faf2 [azurophil granule lumen]
(Danio rerio)
faf2 [azurophil granule lumen]
(Xenopus tropicalis)
Homologues of FAF2 [azurophil granule lumen]
(Dictyostelium discoideum)
Homologues of FAF2 [azurophil granule lumen]
(Saccharomyces cerevisiae)
Cross References
RefSeq
NP_055428.1
OpenTargets
ENSG00000113194
HPA
ENSG00000113194-FAF2
GeneCards
Q96CS3
Ensembl
ENSP00000261942
,
ENSG00000113194
,
ENST00000261942
PRO
Q96CS3
Pharos - Targets
Q96CS3
GlyGen
Q96CS3
PDB
2DAM
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P55072 VCP
8
Me3K315-VCP [cytosol]
(R-HSA-8932209)
VCP [endoplasmic reticulum membrane]
(R-HSA-8943105)
VCP [nucleoplasm]
(R-HSA-5643745)
VCP [secretory granule lumen]
(R-HSA-6801039)
VCP [ficolin-1-rich granule lumen]
(R-HSA-6800425)
VCP [extracellular region]
(R-HSA-6806191)
VCP [azurophil granule lumen]
(R-HSA-6800438)
VCP [cytosol]
(R-HSA-1181251)
0.776
13
UniProt:Q96JH7 VCPIP1
2
p-S131-VCPIP1 [endoplasmic reticulum lumen]
(R-HSA-8940104)
VCPIP1 [endoplasmic reticulum lumen]
(R-HSA-8940103)
0.564
2
UniProt:Q9UBV2 SEL1L
1
SEL1L [endoplasmic reticulum membrane]
(R-HSA-1911545)
0.527
2
UniProt:P40855 PEX19
1
PEX19 [cytosol]
(R-HSA-3009036)
0.527
2
UniProt:P0CG47 UBB
20
UBB(77-152) [endocytic vesicle membrane]
(R-HSA-939253)
UBB(1-76) [endocytic vesicle membrane]
(R-HSA-939231)
UBB(153-228) [endocytic vesicle membrane]
(R-HSA-939171)
Ub-33-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783023)
Ub-110-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6783008)
Ub-186-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783046)
Ub-215-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783002)
Ub-63-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783148)
Ub-139-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6783012)
Ub-158-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783162)
Ub-6-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783014)
Ub-82-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6783015)
Ub-163-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783025)
Ub-87-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6782998)
Ub-11-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783109)
Ub-124-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6783131)
Ub-200-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783100)
Ub-48-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783165)
Ub-182-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783160)
Ub-29-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783070)
0.527
3
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.527
3
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