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FPR1 [azurophil granule membrane]
Stable Identifier
R-HSA-6799143
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
azurophil granule membrane
Synonyms
Formyl peptide receptor, fMet-Leu-Phe receptor, FPR1_HUMAN, FPR
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of azurophil granule membrane proteins (Homo sapiens)
Azurophil granule membrane proteins [azurophil granule membrane] (Homo sapiens)
FPR1 [azurophil granule membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P21462 FPR1
Gene Names
FPR1
Chain
chain:1-350
Reference Genes
BioGPS Gene:2357 FPR1
COSMIC (genes):FPR1 FPR1
CTD Gene:2357 FPR1
dbSNP Gene:2357 FPR1
ENSEMBL:ENSG00000171051 FPR1
ENSEMBL_homo_sapiens_GENE:ENSG00000171051.10 FPR1
HGNC:3826 FPR1
KEGG Gene (Homo sapiens):2357 FPR1
Monarch:2357 FPR1
NCBI Gene:2357 FPR1
OMIM:136537 FPR1
UCSC:P21462 FPR1
Reference Transcript
RefSeq:NM_002029.3 FPR1
RefSeq:NM_001193306.1 FPR1
Other Identifiers
11758095_s_at
11762622_at
16874945
205118_PM_at
205118_at
205119_PM_s_at
205119_s_at
2357
36919_r_at
3729270
3869238
3869239
3869240
3869241
3869242
3869243
3869244
3869245
3869246
3869247
3869248
3869258
8038899
GE61934
GO:0001664
GO:0002376
GO:0002430
GO:0004875
GO:0004930
GO:0004982
GO:0005124
GO:0005515
GO:0005737
GO:0005764
GO:0005773
GO:0005886
GO:0006935
GO:0006954
GO:0007165
GO:0007186
GO:0007188
GO:0007200
GO:0007204
GO:0007263
GO:0016020
GO:0023052
GO:0030667
GO:0031410
GO:0035577
GO:0043226
GO:0050786
GO:0060089
GO:0101003
HMNXSV003007608
ILMN_2092118
M60626_at
PH_hs_0028688
PH_hs_0035311
TC19001787.hg
g4503778_3p_a_at
Participates
as a member of
Azurophil granule membrane proteins [azurophil granule membrane] (Homo sapiens)
Other forms of this molecule
FPR1 [ficolin-1-rich granule membrane]
FPR1 [secretory granule membrane]
FPR1 [plasma membrane]
Inferred To
Homologues of FPR1 [azurophil granule membrane]
(Xenopus tropicalis)
LOC108648060 [azurophil granule membrane]
(Xenopus tropicalis)
LOC100491504 [azurophil granule membrane]
(Xenopus tropicalis)
Fpr1 [azurophil granule membrane]
(Mus musculus)
Fpr1 [azurophil granule membrane]
(Rattus norvegicus)
FPR2 [azurophil granule membrane]
(Canis familiaris)
Cross References
RefSeq
NP_002020.1
,
NP_001180235.1
ZINC - World Drugs
FPR1_HUMAN
Guide to Pharmacology - Targets
222
OpenTargets
ENSG00000171051
ZINC - Substances
FPR1_HUMAN
ZINC target
P21462
PRO
P21462
PDB
7T6T
,
7WVU
,
7EUO
,
7VFX
GeneCards
P21462
HPA
ENSG00000171051-FPR1
Ensembl
ENST00000594900
,
ENSP00000471493
,
ENSP00000472936
,
ENST00000304748
,
ENST00000600815
,
ENST00000595042
,
ENSG00000171051
,
ENSP00000470750
,
ENSP00000302707
Pharos - Targets
P21462
ZINC - Predictions - Purchasable
FPR1_HUMAN
Orphanet
23728
HMDB Protein
HMDBP02151
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O15264 MAPK13
2
p-T180,Y182-MAPK13 [cytosol]
(R-HSA-171022)
MAPK13 [cytosol]
(R-HSA-171012)
0.499
3
UniProt:P25098 GRK2
4
p-S29-ADRBK1 [cytosol]
(R-HSA-9645318)
ADRBK1 [cilium]
(R-HSA-5632504)
p-S29-ADRBK1 [plasma membrane]
(R-HSA-111969)
GRK2 [plasma membrane]
(R-HSA-50270)
0.499
3
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