The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I

Stable Identifier
R-HSA-6799196
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
ReviewStatus
5/5
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The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I
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In the last step, the MCIA complex and it is assumed all of the assembly factors (NDUFAF2-7, TIMMDC1) dissociate from the 980kDa complex to leave mature Complex I (Mckenzie & Ryan 2010, Andrews et al. 2013).
Literature References
PubMed ID Title Journal Year
20552642 Assembly factors of human mitochondrial complex I and their defects in disease

Ryan, MT, McKenzie, M

IUBMB Life 2010
24191001 Assembly factors for the membrane arm of human complex I

Fearnley, IM, Carroll, J, Andrews, B, Walker, JE, Ding, S

Proc. Natl. Acad. Sci. U.S.A. 2013
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Orthologous Events
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Authored
Jassal, B  (2015-09-22)
Reviewed
Meldal, BH  (2015-10-01)
Created
Jassal, B  (2015-09-22)
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