Reactome | TMEM30A [specific granule membrane]

TMEM30A [specific granule membrane]

Stable Identifier

R-HSA-6799526

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

specific granule membrane

Synonyms

Cell cycle control protein 50A, CC50A_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9NV96 TMEM30A

Gene Names

TMEM30A, C6orf67, CDC50A

Chain

initiator methionine:, chain:2-361

Reference Genes

BioGPS Gene:55754 TMEM30A

COSMIC (genes):TMEM30A TMEM30A

CTD Gene:55754 TMEM30A

dbSNP Gene:55754 TMEM30A

ENSEMBL:ENSG00000112697 TMEM30A

HGNC:16667 TMEM30A

KEGG:hsa:55754 TMEM30A

Monarch:55754 TMEM30A

NCBI Gene:55754 TMEM30A

OMIM:611028 TMEM30A

UCSC:Q9NV96 TMEM30A

Reference Transcript

Participates

as a member of

Specific granule membrane proteins [specific granule membrane] (Homo sapiens)

Other forms of this molecule

TMEM30A [plasma membrane]

TMEM30A [azurophil granule membrane]

Inferred To

tmem30a [specific granule membrane] (Xenopus tropicalis)

tmem30ab [specific granule membrane] (Danio rerio)

chat-1 [specific granule membrane] (Caenorhabditis elegans)

TMEM30A [specific granule membrane] (Bos taurus)

TMEM30A [specific granule membrane] (Canis familiaris)

TMEM30A [specific granule membrane] (Dictyostelium discoideum)

TMEM30A [specific granule membrane] (Gallus gallus)

TMEM30A [specific granule membrane] (Plasmodium falciparum)

TMEM30A [specific granule membrane] (Sus scrofa)

mug89 [specific granule membrane] (Schizosaccharomyces pombe)

CDC50 [specific granule membrane] (Saccharomyces cerevisiae)

Tmem30a [specific granule membrane] (Mus musculus)

Tmem30a [specific granule membrane] (Rattus norvegicus)

Cdc50 [specific granule membrane] (Drosophila melanogaster)

Cross References

Guide to Pharmacology - Targets

3154

OpenTargets

ENSG00000112697

ENSEMBL

ENSP00000230461, ENST00000230461, ENSP00000500998, ENST00000674151, ENSG00000112697, ENST00000475111, ENST00000370050, ENSP00000431007, ENSP00000359067

HPA

ENSG00000112697-TMEM30A

GeneCards

TMEM30A

PRO

Q9NV96

Pharos - Targets

Q9NV96

GlyGen

Q9NV96

HMDB Protein

HMDBP13374

PDB

7VGJ, 7VGI, 6K7N, 7VSH, 6K7G, 7VSG, 7BSW, 7BSU, 6K7I, 6K7H, 7BSV, 8OX4, 7BSP, 8OX6, 8OXC, 8OXB, 6LKN, 6K7K, 6K7J, 8OX9, 7BSQ, 6K7L, 8OX7, 7PY4, 6K7M, 8OX5, 7BSS, 8OXA, 8OX8

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P05067 APP	20	APP(672-713) [extracellular region] (R-HSA-879340) APP(672-711) [cytosol] (R-HSA-877188) APP(672-711) [extracellular region] (R-HSA-976740) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-770) [extracellular region] (R-HSA-49335) APP [endoplasmic reticulum lumen] (R-HSA-8956696) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP(18-770) [endosome lumen] (R-HSA-5229077) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-687) [extracellular region] (R-HSA-9010033) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136)	0.564	3
UniProt:P27824 CANX	2	CANX [endoplasmic reticulum lumen] (R-HSA-195906) CANX [lumenal side of endoplasmic reticulum membrane] (R-HSA-983091)	0.527	2

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