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PTX3 [specific granule lumen]
Stable Identifier
R-HSA-6799620
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
specific granule lumen
Synonyms
Pentraxin-related protein PTX3, PTX3_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of specific granule lumen proteins (Homo sapiens)
Specific granule lumen proteins [specific granule lumen] (Homo sapiens)
PTX3 [specific granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P26022 PTX3
Gene Names
PTX3, TNFAIP5, TSG14
Chain
signal peptide:1-17, chain:18-381
Reference Genes
BioGPS Gene:5806 PTX3
COSMIC (genes):PTX3 PTX3
CTD Gene:5806 PTX3
dbSNP Gene:5806 PTX3
ENSEMBL:ENSG00000163661 PTX3
ENSEMBL_homo_sapiens_GENE:ENSG00000163661.4 PTX3
HGNC:9692 PTX3
KEGG Gene (Homo sapiens):5806 PTX3
Monarch:5806 PTX3
NCBI Gene:5806 PTX3
OMIM:602492 PTX3
UCSC:P26022 PTX3
Reference Transcript
RefSeq:NM_002852.3 PTX3
Other Identifiers
11718157_s_at
1491_at
16947357
206157_PM_at
206157_at
2649374
2649375
2649376
2649377
2649378
2649379
5806
8083594
A_14_P137774
A_23_P121064
GE79481
GO:0001550
GO:0001849
GO:0001872
GO:0001878
GO:0002376
GO:0005515
GO:0005576
GO:0005615
GO:0006954
GO:0006955
GO:0008228
GO:0016192
GO:0022414
GO:0030154
GO:0030198
GO:0030312
GO:0031012
GO:0031410
GO:0035580
GO:0042802
GO:0043226
GO:0044793
GO:0044869
GO:0044871
GO:0045087
GO:0045429
GO:0046597
GO:0046790
GO:0048856
GO:0050766
GO:0098542
GO:1901135
GO:1903016
GO:1903019
GO:1904724
HMNXSV003013991
ILMN_1801842
M31166_at
PH_hs_0000274
TC03000862.hg
X97748_s_at
g4506332_3p_at
Participates
as a member of
Specific granule lumen proteins [specific granule lumen] (Homo sapiens)
Other forms of this molecule
PTX3 [extracellular region]
PTX3 [tertiary granule lumen]
Inferred To
Ptx3 [specific granule lumen]
(Mus musculus)
Ptx3 [specific granule lumen]
(Rattus norvegicus)
PTX3 [specific granule lumen]
(Bos taurus)
PTX3 [specific granule lumen]
(Canis familiaris)
PTX3 [specific granule lumen]
(Gallus gallus)
PTX3 [specific granule lumen]
(Sus scrofa)
ptx3 [specific granule lumen]
(Xenopus tropicalis)
Cross References
RefSeq
NP_002843.2
OpenTargets
ENSG00000163661
HPA
ENSG00000163661-PTX3
GeneCards
P26022
Ensembl
ENST00000295927
,
ENSG00000163661
,
ENSP00000295927
PRO
P26022
Pharos - Targets
P26022
PDB
7ZL1
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P09038 FGF2
1
FGF2(10-155) [extracellular region]
(R-HSA-189898)
0.788
16
UniProt:P08603 CFH
1
CFH [extracellular region]
(R-HSA-976788)
0.734
15
UniProt:P0DTC9 N
13
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane]
(R-COV-9729325)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus]
(R-COV-9729339)
N [plasma membrane]
(R-COV-9694356)
SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol]
(R-COV-9756489)
N [cytosol]
(R-COV-9694300)
p-S188,206-N [cytosol]
(R-COV-9729324)
p-8S-N [cytosol]
(R-COV-9729335)
p-8S,2T-N [cytosol]
(R-COV-9729277)
p-11S,2T-N [cytosol]
(R-COV-9729264)
p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729308)
ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729275)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9729341)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729340)
0.558
2
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