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TIMP2 [specific granule lumen]
Stable Identifier
R-HSA-6799625
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
specific granule lumen
Synonyms
Metalloproteinase inhibitor 2, TIMP2_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of specific granule lumen proteins (Homo sapiens)
Specific granule lumen proteins [specific granule lumen] (Homo sapiens)
TIMP2 [specific granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P16035 TIMP2
Gene Names
TIMP2
Chain
signal peptide:1-26, chain:27-220
Reference Genes
BioGPS Gene:7077 TIMP2
COSMIC (genes):TIMP2 TIMP2
CTD Gene:7077 TIMP2
dbSNP Gene:7077 TIMP2
ENSEMBL:ENSG00000035862 TIMP2
ENSEMBL_homo_sapiens_GENE:ENSG00000035862.13 TIMP2
HGNC:11821 TIMP2
KEGG Gene (Homo sapiens):7077 TIMP2
Monarch:7077 TIMP2
NCBI Gene:7077 TIMP2
OMIM:188825 TIMP2
UCSC:P16035 TIMP2
Reference Transcript
RefSeq:NM_003255.4 TIMP2
Other Identifiers
11722786_s_at
11748126_a_at
1375_s_at
16849556
203167_PM_at
203167_at
224560_PM_at
224560_at
231579_PM_s_at
231579_s_at
34722_at
3772662
3772663
3772664
3772665
3772666
3772668
3772669
3772672
3772675
3772711
49080_at
7077
8018966
A_23_P107401
A_33_P3382177
GE618711
GO:0002020
GO:0004857
GO:0005515
GO:0005576
GO:0005615
GO:0008191
GO:0008270
GO:0009725
GO:0030163
GO:0030312
GO:0030414
GO:0031012
GO:0031410
GO:0034097
GO:0035580
GO:0043226
GO:0046872
GO:0051045
GO:0062023
GO:0098772
GO:0140678
GO:1904724
GO:1904813
GO:1905049
HMNXSV003011037
Hs.6441.0.A1_3p_a_at
Hs.6441.0.A1_3p_x_at
ILMN_1721876
ILMN_1749078
M32304_s_at
PH_hs_0030934
TC17002807.hg
g9257247_3p_at
Participates
as a member of
Specific granule lumen proteins [specific granule lumen] (Homo sapiens)
Other forms of this molecule
TIMP2 [tertiary granule lumen]
TIMP2 [extracellular region]
TIMP2 [ficolin-1-rich granule lumen]
Inferred To
TIMP2 [specific granule lumen]
(Bos taurus)
TIMP2 [specific granule lumen]
(Caenorhabditis elegans)
TIMP2 [specific granule lumen]
(Canis familiaris)
TIMP2 [specific granule lumen]
(Danio rerio)
TIMP2 [specific granule lumen]
(Drosophila melanogaster)
TIMP2 [specific granule lumen]
(Gallus gallus)
TIMP2 [specific granule lumen]
(Mus musculus)
TIMP2 [specific granule lumen]
(Rattus norvegicus)
TIMP2 [specific granule lumen]
(Sus scrofa)
TIMP2 [specific granule lumen]
(Xenopus tropicalis)
Homologues of TIMP2 [specific granule lumen]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_003246.1
OpenTargets
ENSG00000035862
GeneCards
P16035
HPA
ENSG00000035862-TIMP2
Ensembl
ENSP00000262768
,
ENSG00000035862
,
ENST00000262768
PRO
P16035
Pharos - Targets
P16035
PDB
4ILW
,
2TMP
,
1BR9
,
1GXD
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P08253 MMP2
5
MMP2(30-66) [extracellular region]
(R-HSA-1604347)
MMP2(30-660) [extracellular region]
(R-HSA-1604364)
MMP2(67-109) [extracellular region]
(R-HSA-1604371)
MMP2(67-660) [extracellular region]
(R-HSA-1604345)
MMP2(110-660) [extracellular region]
(R-HSA-381456)
0.59
2
UniProt:Q9UHD9 UBQLN2
1
UBQLN2 [cytosol]
(R-HSA-8866007)
0.556
3
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