Reactome | PSMD11 [ficolin-1-rich granule lumen]

PSMD11 [ficolin-1-rich granule lumen]

Stable Identifier

R-HSA-6800436

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

ficolin-1-rich granule lumen

Synonyms

26S proteasome non-ATPase regulatory subunit 11, 26S proteasome regulatory subunit S9, 26S proteasome regulatory subunit p44.5

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O00231 PSMD11

Gene Names

PSMD11

Chain

initiator methionine:, chain:2-422

Reference Genes

BioGPS Gene:5717 PSMD11

COSMIC (genes):PSMD11 PSMD11

CTD Gene:5717 PSMD11

dbSNP Gene:5717 PSMD11

ENSEMBL:ENSG00000108671 PSMD11

HGNC:9556 PSMD11

KEGG:hsa:5717 PSMD11

Monarch:5717 PSMD11

NCBI Gene:5717 PSMD11

OMIM:604449 PSMD11

UCSC:O00231 PSMD11

Reference Transcript

Other Identifiers

11753142_a_at

11753982_a_at

1191_s_at

16833139

208776_PM_at

208776_at

208777_PM_s_at

208777_s_at

3717738

3717739

3717740

3717741

3717743

3717745

3717746

3717749

3717750

3717751

3717752

3717753

3717754

3717755

3717757

3717758

3717759

3717761

3717762

3717763

3717764

3717765

3717766

3717767

3717768

3717769

3717770

3717771

3717772

3717774

50989_at

52399_at

5717

58557_at

58558_g_at

61789_i_at

8006392

AB003102_at

A_23_P207600

A_24_P73962

GE53109

GE85882

GO:0000502

GO:0005198

GO:0005515

GO:0005576

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005838

GO:0006511

GO:0008541

GO:0016020

GO:0022624

GO:0030154

GO:0030163

GO:0032991

GO:0034774

GO:0043161

GO:0043226

GO:0043248

GO:0048863

GO:0065003

GO:1904813

HMNXSV003004469

Hs.90744.0.S2_3p_at

ILMN_1800952

PH_hs_0025894

TC17000376.hg

g2150045_3p_a_at

Participates

as a member of

Ficolin-rich granule lumen proteins [ficolin-1-rich granule lumen] (Homo sapiens)

Other forms of this molecule

PSMD11 [cytosol]

PSMD11 [nucleoplasm]

PSMD11 [secretory granule lumen]

PSMD11 [extracellular region]

Inferred To

rpn6 [ficolin-1-rich granule lumen] (Schizosaccharomyces pombe)

psmd11 [ficolin-1-rich granule lumen] (Xenopus tropicalis)

psmd11b [ficolin-1-rich granule lumen] (Danio rerio)

PSMD11 [ficolin-1-rich granule lumen] (Bos taurus)

PSMD11 [ficolin-1-rich granule lumen] (Canis familiaris)

PSMD11 [ficolin-1-rich granule lumen] (Gallus gallus)

PSMD11 [ficolin-1-rich granule lumen] (Plasmodium falciparum)

PSMD11 [ficolin-1-rich granule lumen] (Sus scrofa)

RPN6 [ficolin-1-rich granule lumen] (Saccharomyces cerevisiae)

Rpn6 [ficolin-1-rich granule lumen] (Drosophila melanogaster)

rpn-6.1 [ficolin-1-rich granule lumen] (Caenorhabditis elegans)

psmD11 [ficolin-1-rich granule lumen] (Dictyostelium discoideum)

Psmd11 [ficolin-1-rich granule lumen] (Mus musculus)

Psmd11 [ficolin-1-rich granule lumen] (Rattus norvegicus)

Cross References

RefSeq

NP_001257411.1, NP_002806.2

OpenTargets

ENSG00000108671

ENSEMBL

ENST00000457654, ENSP00000261712, ENSP00000497128, ENST00000261712, ENST00000649012, ENSP00000393185

HPA

ENSG00000108671-PSMD11

PRO

O00231

Pharos - Targets

O00231

GlyGen

O00231

PDB

5VHH, 7W3C, 6MSD, 7QY7, 7QXX, 7QYB, 7W3F, 5VHS, 5GJR, 5VGZ, 7W3A, 6MSB, 7W39, 7W3B, 7W3H, 7W3J, 5T0J, 6MSJ, 5M32, 5VHF, 5T0G, 5LN3, 5VFR, 5VFU, 5VFT, 7QXN, 7QYA, 5GJQ, 5VHI, 6MSE, 8CVT, 7QXP, 7W3M, 7W3K, 6WJN, 6MSG, 7QXW, 7W3I, 5T0C, 7W38, 5L4K, 7W37, 6MSH, 5T0I, 7W3G, 5VFP, 6MSK, 7QXU, 5T0H, 5VFQ, 5VFS, 6WJD

Interactors (37)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Y5K5 UCHL5	2	UCHL5 [cytosol] (R-HSA-1629778) UCHL5 [nucleoplasm] (R-HSA-5689584)	0.788	6
UniProt:P55036 PSMD4	1	PSMD4 [cytosol] (R-HSA-68800)	0.745	5
UniProt:Q9UNM6 PSMD13	5	PSMD13 [cytosol] (R-HSA-68794) PSMD13 [nucleoplasm] (R-HSA-174326) PSMD13 [secretory granule lumen] (R-HSA-6800983) PSMD13 [extracellular region] (R-HSA-6806469) PSMD13 [ficolin-1-rich granule lumen] (R-HSA-6800413)	0.745	6
UniProt:O75832 PSMD10	1	PSMD10 [cytosol] (R-HSA-68788)	0.744	6
UniProt:P51665 PSMD7	5	PSMD7 [cytosol] (R-HSA-68806) PSMD7 [nucleoplasm] (R-HSA-174309) PSMD7 [secretory granule lumen] (R-HSA-6801008) PSMD7 [extracellular region] (R-HSA-6806488) PSMD7 [ficolin-1-rich granule lumen] (R-HSA-6800406)	0.731	5
UniProt:O00232 PSMD12	5	PSMD12 [cytosol] (R-HSA-68792) PSMD12 [nucleoplasm] (R-HSA-174339) PSMD12 [secretory granule lumen] (R-HSA-6800934) PSMD12 [extracellular region] (R-HSA-6806480) PSMD12 [ficolin-1-rich granule lumen] (R-HSA-6800416)	0.731	6
UniProt:P62195 PSMC5	2	PSMC5 [cytosol] (R-HSA-68780) PSMC5 [nucleoplasm] (R-HSA-174312)	0.725	5
UniProt:P49721 PSMB2	2	PSMB2 [cytosol] (R-HSA-68744) PSMB2 [nucleoplasm] (R-HSA-174335)	0.725	4
UniProt:P43686 PSMC4	2	PSMC4 [nucleoplasm] (R-HSA-174315) PSMC4 [cytosol] (R-HSA-68777)	0.669	4
UniProt:Q15008 PSMD6	5	PSMD6 [cytosol] (R-HSA-68804) PSMD6 [nucleoplasm] (R-HSA-174316) PSMD6 [secretory granule lumen] (R-HSA-6801036) PSMD6 [extracellular region] (R-HSA-6806486) PSMD6 [ficolin-1-rich granule lumen] (R-HSA-6800440)	0.667	4
UniProt:O00487 PSMD14	5	PSMD14 [cytosol] (R-HSA-68722) PSMD14 [nucleoplasm] (R-HSA-174329) PSMD14 [secretory granule lumen] (R-HSA-6800926) PSMD14 [extracellular region] (R-HSA-6806511) PSMD14 [ficolin-1-rich granule lumen] (R-HSA-6800419)	0.648	3
UniProt:O43242 PSMD3	5	PSMD3 [cytosol] (R-HSA-68798) PSMD3 [nucleoplasm] (R-HSA-174328) PSMD3 [secretory granule lumen] (R-HSA-6800873) PSMD3 [extracellular region] (R-HSA-6806443) PSMD3 [ficolin-1-rich granule lumen] (R-HSA-6800408)	0.648	4
UniProt:Q13200 PSMD2	5	PSMD2 [cytosol] (R-HSA-68796) PSMD2 [nucleoplasm] (R-HSA-174311) PSMD2 [secretory granule lumen] (R-HSA-6800919) PSMD2 [extracellular region] (R-HSA-6806479) PSMD2 [ficolin-1-rich granule lumen] (R-HSA-6800435)	0.648	4
UniProt:Q99436 PSMB7	7	PSMB7 [cytosol] (R-HSA-68759) PSMB7 [nucleoplasm] (R-HSA-174331) PSMB7 [secretory granule lumen] (R-HSA-6803279) PSMB7 [extracellular region] (R-HSA-6806449) PSMB7 [ficolin-1-rich granule lumen] (R-HSA-6803312) pro-PSMB7 [cytosol] (R-HSA-9908145) PSMB7(1-43) [cytosol] (R-HSA-9908129)	0.643	3
UniProt:P10636-8 MAPT	3	MAPT-8 [cytosol] (R-HSA-9619519) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400)	0.643	6
UniProt:Q16186 ADRM1	2	ADRM1 [cytosol] (R-HSA-5665939) ADRM1 [nucleoplasm] (R-HSA-9918361)	0.643	5
UniProt:P49720 PSMB3	2	PSMB3 [cytosol] (R-HSA-68747) PSMB3 [nucleoplasm] (R-HSA-174341)	0.643	4
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.597	4
UniProt:Q9BRP4 PAAF1	1	PAAF1 [cytosol] (R-HSA-9907973)	0.564	2
UniProt:O43741 PRKAB2	2	PRKAB2 [cytosol] (R-HSA-200413) PRKAB2 [nucleoplasm] (R-HSA-164096)	0.556	3
UniProt:P61201 COPS2	2	COPS2 [cytosol] (R-HSA-416971) COPS2 [nucleoplasm] (R-HSA-5697012)	0.556	3
UniProt:Q99460 PSMD1	4	PSMD1 [extracellular region] (R-HSA-6806194) PSMD1 [azurophil granule lumen] (R-HSA-6798741) PSMD1 [nucleoplasm] (R-HSA-174348) PSMD1 [cytosol] (R-HSA-68786)	0.528	2
UniProt:P60896 SEM1	2	SEM1 [cytosol] (R-HSA-8866674) SEM1 [nucleoplasm] (R-HSA-8866665)	0.528	2
UniProt:P62333 PSMC6	2	PSMC6 [cytosol] (R-HSA-68783) PSMC6 [nucleoplasm] (R-HSA-174319)	0.528	2
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4
UniProt:P25787 PSMA2	5	PSMA2 [cytosol] (R-HSA-68726) PSMA2 [nucleoplasm] (R-HSA-174345) PSMA2 [secretory granule lumen] (R-HSA-6803329) PSMA2 [extracellular region] (R-HSA-6806506) PSMA2 [ficolin-1-rich granule lumen] (R-HSA-6803285)	0.527	2
UniProt:P62191 PSMC1	2	PSMC1 [cytosol] (R-HSA-68768) PSMC1 [nucleoplasm] (R-HSA-174338)	0.527	2
UniProt:P28065 PSMB9	3	pro-PSMB9 [cytosol] (R-HSA-9908136) PSMB9 [cytosol] (R-HSA-68765) PSMB9(1-20) [cytosol] (R-HSA-9908132)	0.527	4
UniProt:P20618 PSMB1	7	PSMB1 [cytosol] (R-HSA-68738) PSMB1 [nucleoplasm] (R-HSA-174347) PSMB1 [secretory granule lumen] (R-HSA-6803287) PSMB1 [extracellular region] (R-HSA-6806477) PSMB1 [ficolin-1-rich granule lumen] (R-HSA-6803340) pro-PSMB1 [cytosol] (R-HSA-9908139) PSMB1(1-28) [cytosol] (R-HSA-9908143)	0.527	3
UniProt:Q16401 PSMD5	1	PSMD5 [cytosol] (R-HSA-68802)	0.527	3
UniProt:Q53HC0 CCD92			0.527	3
UniProt:P17980 PSMC3	5	PSMC3 [cytosol] (R-HSA-68774) PSMC3 [nucleoplasm] (R-HSA-174313) PSMC3 [secretory granule lumen] (R-HSA-6800917) PSMC3 [extracellular region] (R-HSA-6806496) PSMC3 [ficolin-1-rich granule lumen] (R-HSA-6800429)	0.527	2
UniProt:P54578 USP14	1	USP14 [cytosol] (R-HSA-5689541)	0.527	2
UniProt:P28070 PSMB4	4	PSMB4 [cytosol] (R-HSA-68750) PSMB4 [nucleoplasm] (R-HSA-174343) pro-PSMB4 [cytosol] (R-HSA-9908138) PSMB4(1-45) [cytosol] (R-HSA-9908122)	0.527	2
UniProt:Q96LA8 PRMT6	1	PRMT6 [nucleoplasm] (R-HSA-5226884)	0.508	2
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	14
UniProt:P04578-PRO_0000038427 ENV			0.462	2

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