Reactome | KCNAB2 [tertiary granule membrane]

KCNAB2 [tertiary granule membrane]

Stable Identifier

R-HSA-6800890

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

tertiary granule membrane

Synonyms

Voltage-gated potassium channel subunit beta-2, KCAB2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q13303 KCNAB2

Gene Names

KCNAB2, KCNA2B, KCNK2

Chain

chain:1-367

Reference Genes

BioGPS Gene:8514 KCNAB2

COSMIC (genes):KCNAB2 KCNAB2

COSMIC (genes):KCNK2 KCNAB2

CTD Gene:8514 KCNAB2

dbSNP Gene:8514 KCNAB2

ENSEMBL:ENSG00000069424 KCNAB2

HGNC:6229 KCNAB2

KEGG:hsa:8514 KCNAB2

Monarch:8514 KCNAB2

NCBI Gene:8514 KCNAB2

OMIM:601142 KCNAB2

UCSC:Q13303 KCNAB2

Reference Transcript

Other Identifiers

11737785_a_at

11737786_a_at

11745714_a_at

11761657_at

11763315_a_at

16658312

203402_PM_at

203402_at

211791_PM_s_at

211791_s_at

2318087

2318088

2318089

2318091

2318092

2318093

2318094

2318095

2318097

2318098

2318099

2318100

2318101

2318102

2318103

2318104

2318105

2318106

2318107

2318111

2318112

2318113

2318114

2318115

2318116

2318117

2318118

2318119

2318120

2318121

2318122

2318123

2318124

2318125

2318126

2318127

2318128

2318129

2318130

2318131

2318133

2318140

2318142

31900_at

31901_at

7897236

8514

A_14_P104015

A_23_P501232

A_24_P151

A_33_P3228190

GE61729

GO:0003824

GO:0004033

GO:0005215

GO:0005249

GO:0005515

GO:0005737

GO:0005829

GO:0005856

GO:0005874

GO:0005886

GO:0006813

GO:0008076

GO:0009898

GO:0015459

GO:0016020

GO:0016491

GO:0030424

GO:0034220

GO:0035579

GO:0043005

GO:0043226

GO:0044224

GO:0044325

GO:0045202

GO:0055085

GO:0055086

GO:0070821

GO:0070995

GO:0071805

GO:0098772

GO:0098900

GO:1901379

GO:1990002

GO:1990031

GO:2000008

HMNXSV003009364

HMNXSV003050519

Hs.298184.0.S3_3p_at

ILMN_1725496

ILMN_2342762

PH_hs_0025789

U33429_at

g2827465_3p_a_at

Participates

as a member of

Tertiary granule membrane proteins [tertiary granule membrane] (Homo sapiens)

Other forms of this molecule

KCNAB2 [specific granule membrane]

KCNAB2 [plasma membrane]

Inferred To

Hk [tertiary granule membrane] (Drosophila melanogaster)

KCNAB2 [tertiary granule membrane] (Bos taurus)

KCNAB2 [tertiary granule membrane] (Canis familiaris)

KCNAB2 [tertiary granule membrane] (Gallus gallus)

KCNAB2 [tertiary granule membrane] (Mus musculus)

KCNAB2 [tertiary granule membrane] (Rattus norvegicus)

KCNAB2 [tertiary granule membrane] (Schizosaccharomyces pombe)

KCNAB2 [tertiary granule membrane] (Sus scrofa)

Cross References

OpenTargets

ENSG00000069424

ENSEMBL

ENST00000666163, ENST00000669250, ENSP00000164247, ENST00000671676, ENST00000668559, ENST00000602612, ENSP00000499370, ENSP00000400285, ENSP00000499485, ENSP00000367337, ENST00000378092, ENSP00000367323, ENSP00000367332, ENSP00000499361, ENSP00000499496, ENST00000378097, ENST00000458166, ENSP00000396167, ENST00000164247, ENST00000378083, ENSP00000318772, ENST00000428161, ENST00000352527, ENSP00000473602

HPA

ENSG00000069424-KCNAB2

PRO

Q13303

Pharos - Targets

Q13303

Orphanet

KCNAB2

GlyGen

Q13303

HMDB Protein

HMDBP10778

PDB

1ZSX, 7WF4, 7WF3, 7EJ2, 7EJ1

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:P05067 APP	20	APP(672-713) [extracellular region] (R-HSA-879340) APP(672-711) [cytosol] (R-HSA-877188) APP(672-711) [extracellular region] (R-HSA-976740) APP [endoplasmic reticulum lumen] (R-HSA-8956696) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP(18-770) [endosome lumen] (R-HSA-5229077) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-687) [extracellular region] (R-HSA-9010033) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-770) [extracellular region] (R-HSA-49335) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136)	0.556	3

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