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TOM1 [specific granule membrane]
Stable Identifier
R-HSA-6800923
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
specific granule membrane
Synonyms
Target of Myb protein 1, TOM1_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of specific granule membrane proteins (Homo sapiens)
Specific granule membrane proteins [specific granule membrane] (Homo sapiens)
TOM1 [specific granule membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O60784 TOM1
Gene Names
TOM1
Chain
chain:1-492
Reference Genes
BioGPS Gene:10043 TOM1
COSMIC (genes):TOM1 TOM1
CTD Gene:10043 TOM1
dbSNP Gene:10043 TOM1
ENSEMBL:ENSG00000100284 TOM1
HGNC:11982 TOM1
KEGG:hsa:10043 TOM1
Monarch:10043 TOM1
NCBI Gene:10043 TOM1
OMIM:604700 TOM1
UCSC:O60784 TOM1
Reference Transcript
RefSeq:NM_001135730.2 TOM1
RefSeq:NM_001135732.2 TOM1
RefSeq:NM_005488.3 TOM1
RefSeq:NM_001135729.2 TOM1
Participates
as a member of
Specific granule membrane proteins [specific granule membrane] (Homo sapiens)
Other forms of this molecule
TOM1 [azurophil granule membrane]
TOM1 [plasma membrane]
Inferred To
DmTOM1 [specific granule membrane]
(Drosophila melanogaster)
Tom1 [specific granule membrane]
(Mus musculus)
Tom1 [specific granule membrane]
(Rattus norvegicus)
TOM1 [specific granule membrane]
(Bos taurus)
TOM1 [specific granule membrane]
(Canis familiaris)
TOM1 [specific granule membrane]
(Gallus gallus)
TOM1 [specific granule membrane]
(Sus scrofa)
tmyb-1 [specific granule membrane]
(Caenorhabditis elegans)
tom1 [specific granule membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_005479.1
,
NP_001129202.1
,
NP_001129204.1
,
NP_001129201.1
ENSEMBL
ENST00000411850
,
ENSG00000100284
,
ENST00000449058
,
ENST00000447733
,
ENSP00000413697
,
ENST00000425375
,
ENSP00000394924
,
ENSP00000398876
,
ENSP00000394466
OpenTargets
ENSG00000100284
GeneCards
TOM1
HPA
ENSG00000100284-TOM1
PRO
O60784
Pharos - Targets
O60784
Orphanet
TOM1
PDB
1WRD
,
2N2N
,
6J56
,
1ELK
,
2N9D
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9H0E2 TOLLIP
4
TOLLIP [cytosol]
(R-HSA-446885)
TOLLIP [azurophil granule lumen]
(R-HSA-6799709)
TOLLIP [extracellular region]
(R-HSA-6800448)
TOLLIP [specific granule lumen]
(R-HSA-6799719)
0.888
9
UniProt:P0CG53
20
UBB [endocytic vesicle membrane]
(R-BTA-939253)
UBB [endocytic vesicle membrane]
(R-BTA-939231)
UBB [endocytic vesicle membrane]
(R-BTA-939171)
UBB [mitochondrial outer membrane]
(R-BTA-6783023)
UBB [mitochondrial outer membrane]
(R-BTA-6783008)
UBB [mitochondrial outer membrane]
(R-BTA-6783046)
UBB [mitochondrial outer membrane]
(R-BTA-6783002)
UBB [mitochondrial outer membrane]
(R-BTA-6783148)
UBB [mitochondrial outer membrane]
(R-BTA-6783012)
UBB [mitochondrial outer membrane]
(R-BTA-6783162)
UBB [mitochondrial outer membrane]
(R-BTA-6783014)
UBB [mitochondrial outer membrane]
(R-BTA-6783015)
UBB [mitochondrial outer membrane]
(R-BTA-6783025)
UBB [mitochondrial outer membrane]
(R-BTA-6782998)
UBB [mitochondrial outer membrane]
(R-BTA-6783109)
UBB [mitochondrial outer membrane]
(R-BTA-6783131)
UBB [mitochondrial outer membrane]
(R-BTA-6783100)
UBB [mitochondrial outer membrane]
(R-BTA-6783165)
UBB [mitochondrial outer membrane]
(R-BTA-6783160)
UBB [mitochondrial outer membrane]
(R-BTA-6783070)
0.743
6
UniProt:Q7Z3T8 ZFYVE16
1
ZFYVE16 [early endosome membrane]
(R-HSA-201645)
0.736
6
UniProt:Q9UM54 MYO6
3
MYO6 [plasma membrane]
(R-HSA-3006691)
MYO6 [lysosomal membrane]
(R-HSA-3006694)
MYO6 [cytosol]
(R-HSA-3006692)
0.527
2
UniProt:P03372 ESR1
10
ESR1 [cytosol]
(R-HSA-9020968)
ESR1 [nucleoplasm]
(R-HSA-446168)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
p-S167-ESR1 [cytosol]
(R-HSA-9841254)
p-S167-ESR1 [nucleoplasm]
(R-HSA-9841867)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
0.527
3
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