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ACTR2 [ficolin-1-rich granule lumen]
Stable Identifier
R-HSA-6800937
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
ficolin-1-rich granule lumen
Synonyms
ARP2
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of ficolin-rich granule lumen proteins (Homo sapiens)
Ficolin-rich granule lumen proteins [ficolin-1-rich granule lumen] (Homo sapiens)
ACTR2 [ficolin-1-rich granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P61160 ACTR2
Gene Names
ACTR2, ARP2
Chain
chain:1-394
Reference Genes
BioGPS Gene:10097 ACTR2
COSMIC (genes):ACTR2 ACTR2
CTD Gene:10097 ACTR2
dbSNP Gene:10097 ACTR2
ENSEMBL:ENSG00000138071 ACTR2
ENSEMBL_homo_sapiens_GENE:ENSG00000138071.15 ACTR2
HGNC:169 ACTR2
KEGG Gene (Homo sapiens):10097 ACTR2
Monarch:10097 ACTR2
NCBI Gene:10097 ACTR2
OMIM:604221 ACTR2
UCSC:P61160 ACTR2
Reference Transcript
RefSeq:NM_001005386.2 ACTR2
RefSeq:NM_005722.3 ACTR2
Other Identifiers
10097
11739031_s_at
11739032_x_at
11739033_a_at
11739034_s_at
11739035_x_at
11743580_s_at
11743581_s_at
11745442_x_at
11748806_x_at
1554390_PM_s_at
1554390_s_at
1558015_PM_s_at
1558015_s_at
16880758
200727_PM_s_at
200727_s_at
200728_PM_at
200728_at
200729_PM_s_at
200729_s_at
2485788
2485789
2485793
2485798
2485800
2485802
2485803
2485804
2485806
2485807
2485809
2485810
2485811
2485812
35733_at
35734_at
3826229
3826230
3826232
3826236
3882733
3940267
8042337
A_23_P377376
A_24_P276947
GE54067
GO:0000166
GO:0000910
GO:0002376
GO:0003779
GO:0005198
GO:0005200
GO:0005515
GO:0005524
GO:0005576
GO:0005615
GO:0005634
GO:0005694
GO:0005737
GO:0005764
GO:0005773
GO:0005829
GO:0005856
GO:0005885
GO:0005925
GO:0005938
GO:0006281
GO:0006310
GO:0006351
GO:0006355
GO:0007010
GO:0007018
GO:0007059
GO:0007163
GO:0008092
GO:0008356
GO:0010592
GO:0015629
GO:0016020
GO:0016344
GO:0016482
GO:0022414
GO:0030036
GO:0030478
GO:0031410
GO:0033206
GO:0034314
GO:0035578
GO:0035861
GO:0042995
GO:0043226
GO:0044782
GO:0045944
GO:0051015
GO:0051321
GO:0051653
GO:0060271
GO:0070062
GO:0071346
GO:0098542
GO:0140013
GO:1904813
GO:1905168
HMNXSV003018844
Hs.42915.0.A3_3p_at
Hs2.12755.1.S1_3p_s_at
Hs2.393201.2.S1_3p_s_at
ILMN_2388605
PH_hs_0030017
TC02000378.hg
g5031570_3p_a_at
Participates
as a member of
Ficolin-rich granule lumen proteins [ficolin-1-rich granule lumen] (Homo sapiens)
Other forms of this molecule
ACTR2 [azurophil granule lumen]
ACTR2 [extracellular region]
ACTR2 [cytosol]
Inferred To
Homologues of ACTR2 [ficolin-1-rich granule lumen]
(Danio rerio)
ACTR2 [ficolin-1-rich granule lumen]
(Bos taurus)
ACTR2 [ficolin-1-rich granule lumen]
(Caenorhabditis elegans)
ACTR2 [ficolin-1-rich granule lumen]
(Canis familiaris)
ACTR2 [ficolin-1-rich granule lumen]
(Danio rerio)
ACTR2 [ficolin-1-rich granule lumen]
(Dictyostelium discoideum)
ACTR2 [ficolin-1-rich granule lumen]
(Drosophila melanogaster)
ACTR2 [ficolin-1-rich granule lumen]
(Gallus gallus)
ACTR2 [ficolin-1-rich granule lumen]
(Mus musculus)
ACTR2 [ficolin-1-rich granule lumen]
(Rattus norvegicus)
ACTR2 [ficolin-1-rich granule lumen]
(Saccharomyces cerevisiae)
ACTR2 [ficolin-1-rich granule lumen]
(Schizosaccharomyces pombe)
ACTR2 [ficolin-1-rich granule lumen]
(Sus scrofa)
Cross References
RefSeq
NP_005713.1
,
NP_001005386.1
OpenTargets
ENSG00000138071
GeneCards
P61160
HPA
ENSG00000138071-ACTR2
Ensembl
ENST00000260641
,
ENSG00000138071
,
ENSP00000367220
,
ENSP00000260641
,
ENST00000377982
PRO
P61160
Pharos - Targets
P61160
PDB
6YW7
,
6UHC
,
6YW6
,
8P94
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.706
15
UniProt:Q14247 CTTN
2
CTTN [cytosol]
(R-HSA-201894)
p-S113-CTTN [cytosol]
(R-HSA-442842)
0.527
2
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