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RABGGTA [plasma membrane]
Stable Identifier
R-HSA-6801086
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Geranylgeranyl transferase type-2 subunit alpha, Rab geranyl-geranyltransferase subunit alpha
Icon
Locations in the PathwayBrowser for interactor UniProt:A1L0T0 HACL2
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
TP53 Regulates Transcription of Cell Death Genes (Homo sapiens)
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain (Homo sapiens)
RABGGTA binds RABGGTB (Homo sapiens)
RABGGTA [plasma membrane] (Homo sapiens)
TP53 stimulates RABGGTA expression (Homo sapiens)
RABGGTA [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q92696 RABGGTA
Gene Names
RABGGTA
Chain
chain:1-567
Reference Genes
BioGPS Gene:5875 RABGGTA
COSMIC (genes):RABGGTA RABGGTA
CTD Gene:5875 RABGGTA
dbSNP Gene:5875 RABGGTA
ENSEMBL:ENSG00000100949 RABGGTA
HGNC:9795 RABGGTA
KEGG:hsa:5875 RABGGTA
Monarch:5875 RABGGTA
NCBI Gene:5875 RABGGTA
OMIM:601905 RABGGTA
UCSC:Q92696 RABGGTA
Reference Transcript
RefSeq:NM_004581.5 RABGGTA
RefSeq:NM_182836.2 RABGGTA
Other Identifiers
100_g_at
111_at
11721186_a_at
11737759_x_at
11751406_a_at
11755532_x_at
16791244
203573_PM_s_at
203573_s_at
3558072
3558073
3558074
3558075
3558076
3558077
3558078
3558079
3558080
3558081
3558082
3558083
3558084
3558085
3558086
3558087
3558088
3558089
3558090
3558091
3558092
3558093
3558094
3558095
3558096
3558097
3558098
3558099
3558100
3558101
3558102
3558103
3558104
3558105
3558106
3558107
3558108
5875
7978239
A_23_P54223
GE60249
GO:0003824
GO:0004659
GO:0004661
GO:0004663
GO:0005515
GO:0005737
GO:0005829
GO:0005886
GO:0005968
GO:0007601
GO:0008270
GO:0008318
GO:0016740
GO:0018342
GO:0018344
GO:0031267
GO:0036211
GO:0050877
GO:0097354
GO:0140096
HMNXSV003056029
ILMN_1770329
ILMN_2299221
PH_hs_0032991
TC14000972.hg
Y08200_at
g4759015_3p_a_at
g4759015_3p_x_at
Participates
as a component of
RGGT [plasma membrane] (Homo sapiens)
as an input of
RABGGTA binds RABGGTB (Homo sapiens)
as an output of
TP53 stimulates RABGGTA expression (Homo sapiens)
Other forms of this molecule
RABGGTA [cytosol]
Inferred To
RabGGTa [plasma membrane]
(Drosophila melanogaster)
bet4 [plasma membrane]
(Schizosaccharomyces pombe)
RABGGTA [plasma membrane]
(Bos taurus)
RABGGTA [plasma membrane]
(Caenorhabditis elegans)
RABGGTA [plasma membrane]
(Canis familiaris)
RABGGTA [plasma membrane]
(Plasmodium falciparum)
RABGGTA [plasma membrane]
(Sus scrofa)
BET4 [plasma membrane]
(Saccharomyces cerevisiae)
rabggta [plasma membrane]
(Danio rerio)
rabggta [plasma membrane]
(Dictyostelium discoideum)
rabggta [plasma membrane]
(Xenopus tropicalis)
Rabggta [plasma membrane]
(Mus musculus)
Rabggta [plasma membrane]
(Rattus norvegicus)
Cross References
OpenTargets
ENSG00000100949
ENSEMBL
ENSP00000496595
,
ENSP00000494636
,
ENST00000646658
,
ENSG00000285193
,
ENSP00000382341
,
ENSP00000216840
,
ENST00000216840
,
ENST00000644383
,
ENSG00000100949
,
ENST00000399409
HPA
ENSG00000100949-RABGGTA
GeneCards
RABGGTA
PRO
Q92696
Pharos - Targets
Q92696
GlyGen
Q92696
HMDB Protein
HMDBP11878
Interactors (19)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P53611 RABGGTB
2
RABGGTB [plasma membrane]
(R-HSA-6801098)
RABGGTB [cytosol]
(R-HSA-8870419)
0.8
8
UniProt:P24386 CHM
1
CHM [cytosol]
(R-HSA-6801097)
0.744
6
UniProt:P20339 RAB5A
7
RAB5A [cytosol]
(R-HSA-2201187)
GGC-RAB5A [macropinosome membrane]
(R-HSA-9837697)
RAB5A [endosome membrane]
(R-HSA-452257)
RAB5A [early endosome membrane]
(R-HSA-2130175)
GGC-RAB5A [cytosol]
(R-HSA-8870432)
GGC-RAB5A [early endosome membrane]
(R-HSA-8875323)
GGC-RAB5A [clathrin-coated endocytic vesicle membrane]
(R-HSA-8871125)
0.671
5
UniProt:P26374 CHML
1
CHML [cytosol]
(R-HSA-8870443)
0.643
4
UniProt:O15498 YKT6
5
PalmC-YKT6 [endoplasmic reticulum membrane]
(R-HSA-5688145)
PalmC-YKT6 [ER to Golgi transport vesicle membrane]
(R-HSA-5688557)
PalmC-YKT6 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5688558)
PalmC-YKT6 [transport vesicle]
(R-HSA-6808794)
PalmC-YKT6 [Golgi membrane]
(R-HSA-6808792)
0.527
3
UniProt:Q9UQV4 LAMP3
0.527
2
UniProt:Q9NP90 RAB9B
7
RAB9B [transport vesicle]
(R-HSA-6814621)
RAB9B [trans-Golgi network membrane]
(R-HSA-6814620)
GGC-RAB9B [trans-Golgi network membrane]
(R-HSA-8876089)
GGC-RAB9B [cytosol]
(R-HSA-8874076)
RAB9B [cytosol]
(R-HSA-6813907)
RAB9B [plasma membrane]
(R-HSA-6804810)
RAB9B [secretory granule membrane]
(R-HSA-6804773)
0.527
4
UniProt:O14966 RAB29
2
RAB29 [cytosol]
(R-HSA-8873713)
GGC-RAB29 [cytosol]
(R-HSA-8873957)
0.527
3
UniProt:P51151 RAB9A
5
RAB9A [transport vesicle]
(R-HSA-6814618)
RAB9A [trans-Golgi network membrane]
(R-HSA-6814616)
GGC-RAB9A [trans-Golgi network membrane]
(R-HSA-8876087)
GGC-RAB9A [cytosol]
(R-HSA-8874069)
RAB9A [cytosol]
(R-HSA-6813904)
0.527
3
UniProt:Q9BVM2 DPCD
0.527
2
UniProt:Q13636 RAB31
5
GGC-RAB31 [early endosome membrane]
(R-HSA-8877278)
GGC-RAB31 [cytosol]
(R-HSA-8873974)
RAB31 [cytosol]
(R-HSA-8873690)
RAB31 [plasma membrane]
(R-HSA-6804813)
RAB31 [secretory granule membrane]
(R-HSA-6804797)
0.527
3
UniProt:Q9NRW1 RAB6B
6
RAB6B [endoplasmic reticulum membrane]
(R-HSA-8849252)
RAB6B [trans-Golgi network membrane]
(R-HSA-6810985)
RAB6B [Golgi membrane]
(R-HSA-8849249)
GGC-RAB6B [trans-Golgi network membrane]
(R-HSA-8876081)
GGC-RAB6B [cytosol]
(R-HSA-8874055)
RAB6B [cytosol]
(R-HSA-6810983)
0.527
3
UniProt:P04406 GAPDH
1
GAPDH [cytosol]
(R-HSA-70428)
0.527
2
UniProt:Q13637 RAB32
3
GGC-RAB32 [melanosome membrane]
(R-HSA-8877737)
GGC-RAB32 [cytosol]
(R-HSA-8873980)
RAB32 [cytosol]
(R-HSA-8873696)
0.527
4
UniProt:A1L0T0 HACL2
0.527
4
UniProt:Q96AH8 RAB7B
4
RAB7B [late endosome membrane]
(R-HSA-8854158)
GGC-RAB7B [lysosomal membrane]
(R-HSA-8877450)
GGC-RAB7B [cytosol]
(R-HSA-8874059)
RAB7B [cytosol]
(R-HSA-8873707)
0.527
3
UniProt:P62820 RAB1A
8
p-T195-RAB1A [Golgi membrane]
(R-HSA-2172190)
RAB1A [Golgi membrane]
(R-HSA-2167938)
RAB1A [cytosol]
(R-HSA-5685725)
RAB1A [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-6807766)
RAB1A [transport vesicle]
(R-HSA-6808796)
GGC-RAB1A [cytosol]
(R-HSA-8870424)
GGC-RAB1A [transport vesicle membrane]
(R-HSA-8877472)
RAB1A [endoplasmic reticulum membrane]
(R-HSA-6810974)
0.527
2
UniProt:Q9H0U4 RAB1B
8
RAB1B [endoplasmic reticulum membrane]
(R-HSA-6810977)
GGC-RAB1B [transport vesicle membrane]
(R-HSA-8877470)
GGC-RAB1B [cytosol]
(R-HSA-8870426)
RAB1B [transport vesicle]
(R-HSA-6808799)
RAB1B [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-6807768)
RAB1B [cytosol]
(R-HSA-5685727)
RAB1B [Golgi membrane]
(R-HSA-2422381)
p-T191-RAB1B [Golgi membrane]
(R-HSA-2422374)
0.527
3
UniProt:Q15771 RAB30
3
RAB30 [Golgi membrane]
(R-HSA-8849598)
GGC-RAB30 [cytosol]
(R-HSA-8873972)
RAB30 [cytosol]
(R-HSA-8873677)
0.527
2
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