Reactome | DYNLT1 [ficolin-1-rich granule lumen]

DYNLT1 [ficolin-1-rich granule lumen]

Stable Identifier

R-HSA-6801487

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

ficolin-1-rich granule lumen

Synonyms

Dynein light chain Tctex-type 1, DYLT1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P63172 DYNLT1

Gene Names

DYNLT1, TCTEL1, TCTEX-1, TCTEX1

Chain

chain:1-113

Reference Genes

BioGPS Gene:6993 DYNLT1

COSMIC (genes):DYNLT1 DYNLT1

CTD Gene:6993 DYNLT1

dbSNP Gene:6993 DYNLT1

ENSEMBL:ENSG00000146425 DYNLT1

HGNC:11697 DYNLT1

KEGG Gene (Homo sapiens):6993 DYNLT1

Monarch:6993 DYNLT1

NCBI Gene:6993 DYNLT1

OMIM:601554 DYNLT1

UCSC:P63172 DYNLT1

Reference Transcript

RefSeq:NM_006519.3 DYNLT1

Other Identifiers

0003990711

11716583_a_at

11716584_x_at

11753785_x_at

17025177

201999_s_at

2981875

2981876

2981879

2981882

2981885

2981889

2981890

3710718

6993

8130499

946_at

A_23_P8185

D50663_at

GE61149

GO:0000132

GO:0000278

GO:0000902

GO:0002376

GO:0003674

GO:0005515

GO:0005575

GO:0005576

GO:0005622

GO:0005737

GO:0005739

GO:0005794

GO:0005819

GO:0005856

GO:0005868

GO:0005874

GO:0005881

GO:0006810

GO:0007005

GO:0007010

GO:0007049

GO:0007165

GO:0007399

GO:0008022

GO:0008150

GO:0008219

GO:0008277

GO:0010976

GO:0015031

GO:0016032

GO:0016192

GO:0016358

GO:0019060

GO:0030027

GO:0030154

GO:0030286

GO:0031410

GO:0032991

GO:0034774

GO:0035022

GO:0035795

GO:0042592

GO:0042802

GO:0043025

GO:0043087

GO:0043226

GO:0043312

GO:0043657

GO:0044295

GO:0044403

GO:0046718

GO:0048812

GO:0048856

GO:0050768

GO:0051301

GO:0051493

GO:0060548

GO:0061024

GO:0061564

GO:0075521

GO:0075606

GO:0099503

GO:1904813

HMNXSV003016472

ILMN_1678766

PH_hs_0013701

TC06002263.hg

g5730084_3p_a_at

Participates

as a member of

Ficolin-rich granule lumen proteins [ficolin-1-rich granule lumen] (Homo sapiens)

Other forms of this molecule

DYNLT1 [secretory granule lumen]

DYNLT1 [extracellular region]

Inferred To

dlc1 [ficolin-1-rich granule lumen] (Schizosaccharomyces pombe)

dylt-1 [ficolin-1-rich granule lumen] (Caenorhabditis elegans)

DYNLT1 [ficolin-1-rich granule lumen] (Bos taurus)

DYNLT1 [ficolin-1-rich granule lumen] (Canis familiaris)

DYNLT1 [ficolin-1-rich granule lumen] (Gallus gallus)

DYNLT1 [ficolin-1-rich granule lumen] (Plasmodium falciparum)

DYNLT1 [ficolin-1-rich granule lumen] (Sus scrofa)

Homologues of DYNLT1 [ficolin-1-rich granule lumen] (Bos taurus)

Dynlt1 [ficolin-1-rich granule lumen] (Mus musculus)

Dynlt1 [ficolin-1-rich granule lumen] (Rattus norvegicus)

Dlc90F [ficolin-1-rich granule lumen] (Drosophila melanogaster)

dlcA [ficolin-1-rich granule lumen] (Dictyostelium discoideum)

dynlt1b [ficolin-1-rich granule lumen] (Danio rerio)

dynlt1 [ficolin-1-rich granule lumen] (Xenopus tropicalis)

Cross References

RefSeq

NP_006510.1

OpenTargets

ENSG00000146425

HPA

ENSG00000146425-DYNLT1

GeneCards

P63172

Ensembl

ENSP00000356056, ENSG00000146425, ENST00000367089

PRO

P63172

Pharos - Targets

P63172

GlyGen

P63172

PDB

5JPW

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P12814 ACTN1	3	ACTN1 [cytosol] (R-HSA-354096) ACTN1 [platelet alpha granule lumen] (R-HSA-349724) ACTN1 [extracellular region] (R-HSA-349722)	0.556	3
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:O00560 SDCBP	3	SDCBP [extracellular region] (R-HSA-6806206) SDCBP [azurophil granule lumen] (R-HSA-6799372) SDCBP [cytosol] (R-HSA-373639)	0.556	3
UniProt:Q9UBK9 UXT	1	UXT [nucleoplasm] (R-HSA-9007484)	0.556	3
UniProt:P07196 NEFL	1	NEFL [cytosol] (R-HSA-432284)	0.556	3
UniProt:P43034 PAFAH1B1	1	PAFAH1B1 [cytosol] (R-HSA-376249)	0.508	2
UniProt:Q99873 PRMT1	2	PRMT1 [cytosol] (R-HSA-9632173) PRMT1 [nucleoplasm] (R-HSA-3215140)	0.508	2
UniProt:P08670 VIM	11	VIM(2-85) [cytosol] (R-HSA-350264) VIM(86-466) [cytosol] (R-HSA-350294) VIM(430-466) [cytosol] (R-HSA-350316) VIM(2-429) [cytosol] (R-HSA-350317) VIM(260-466) [cytosol] (R-HSA-350314) VIM(2-259) [cytosol] (R-HSA-350323) VIM [cytosol] (R-HSA-201600) Vimentin [late endosome lumen] (R-HSA-9660019) Vimentin [microtubule organizing center] (R-HSA-9657898) Vimentin [cytosol] (R-HSA-9646687) Vimentin [lysosomal lumen] (R-HSA-9659977)	0.508	2

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