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CST3 [extracellular region]
Stable Identifier
R-HSA-6801534
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Cystatin-C, CYTC_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of ficolin-rich granule lumen proteins (Homo sapiens)
Ficolin-rich granule lumen proteins [extracellular region] (Homo sapiens)
CST3 [extracellular region] (Homo sapiens)
Exocytosis of tertiary granule lumen proteins (Homo sapiens)
Tertiary granule lumen proteins [extracellular region] (Homo sapiens)
CST3 [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P01034 CST3
Gene Names
CST3
Chain
signal peptide:1-26, chain:27-146
Reference Genes
BioGPS Gene:1471 CST3
COSMIC (genes):CST3 CST3
CTD Gene:1471 CST3
dbSNP Gene:1471 CST3
ENSEMBL:ENSG00000101439 CST3
ENSEMBL_homo_sapiens_GENE:ENSG00000101439.9 CST3
HGNC:2475 CST3
KEGG Gene (Homo sapiens):1471 CST3
Monarch:1471 CST3
NCBI Gene:1471 CST3
OMIM:604312 CST3
UCSC:P01034 CST3
Reference Transcript
RefSeq:NM_000099.3 CST3
RefSeq:NM_001288614.1 CST3
Other Identifiers
11715358_x_at
11757288_s_at
1471
16917939
201360_PM_at
201360_at
230343_PM_at
230343_at
237623_PM_at
237623_at
3901297
3901298
3901299
3901300
3901301
3901302
3901303
3901308
3901309
3901310
3901311
3901312
3901313
3901314
3901318
3901319
3901320
3901321
3901322
3901323
45850_at
8065403
A_24_P216294
A_33_P3228266
A_33_P3228271
GE594855
GE59773
GE868472
GO:0001540
GO:0002020
GO:0004866
GO:0004869
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005783
GO:0005788
GO:0005794
GO:0005886
GO:0006952
GO:0010466
GO:0010711
GO:0010716
GO:0030163
GO:0030198
GO:0030414
GO:0031410
GO:0031982
GO:0034103
GO:0042802
GO:0043226
GO:0045861
GO:0048856
GO:0060311
GO:0060313
GO:0070062
GO:0097435
GO:0098772
GO:1901135
GO:1904724
GO:1904813
HMNXSV003024512
HMNXSV003051337
Hs.211061.0.A1_3p_at
Hs.28773.0.A1_3p_at
ILMN_1800354
M27891_at
PH_hs_0015700
TC20000715.hg
g4503106_3p_at
Participates
as a member of
Ficolin-rich granule lumen proteins [extracellular region] (Homo sapiens)
Tertiary granule lumen proteins [extracellular region] (Homo sapiens)
Other forms of this molecule
Variant cystatin-C [extracellular region]
CST3 [endoplasmic reticulum lumen]
p-CST3 [endoplasmic reticulum lumen]
CST3 [tertiary granule lumen]
CST3 [ficolin-1-rich granule lumen]
Inferred To
LOC607874 [extracellular region]
(Canis familiaris)
CST3 [extracellular region]
(Bos taurus)
CST3 [extracellular region]
(Gallus gallus)
CST3 [extracellular region]
(Sus scrofa)
cpi-2 [extracellular region]
(Caenorhabditis elegans)
Cst3 [extracellular region]
(Mus musculus)
Cst3 [extracellular region]
(Rattus norvegicus)
LOC561073 [extracellular region]
(Danio rerio)
si:busm1-57f23.1 [extracellular region]
(Danio rerio)
Homologues of CST3 [extracellular region]
(Danio rerio)
Cross References
RefSeq
NP_000090.1
,
NP_001275543.1
OpenTargets
ENSG00000101439
HPA
ENSG00000101439-CST3
GeneCards
P01034
Ensembl
ENSG00000101439
,
ENST00000376925
,
ENST00000398409
,
ENSP00000381446
,
ENSP00000366124
,
ENSP00000381448
,
ENST00000398411
PRO
P01034
Pharos - Targets
P01034
Orphanet
15814
PDB
3QRD
,
3PS8
,
1R4C
,
1TIJ
,
6ROA
,
3GAX
,
1G96
,
3NX0
,
3S67
,
6RPV
,
3SVA
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P05067 APP
20
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-713) [extracellular region]
(R-HSA-879340)
0.556
3
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