SND1(1-593)-BRAF(381-766) fusion [cytosol]

Stable Identifier
R-HSA-6802469
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
22745804 A novel SND1-BRAF fusion confers resistance to c-Met inhibitor PF-04217903 in GTL16 cells through [corrected] MAPK activation

Buckman, D, Pavlicek, A, Aparicio, S, Rejto, PA, Srinivasa, SP, Lee, NV, Ye, J, Ching, KA, Zhao, Y, Christensen, JG, Bagrodia, S, Lira, ME

PLoS ONE 2012
External Reference Information
External Reference
UniProt:Q7KZF4 SND1
Gene Names
SND1, TDRD11
Chain
initiator methionine:, chain:2-910
Reference Genes
BioGPS Gene:27044 SND1
COSMIC (genes):SND1 SND1
CTD Gene:27044 SND1
dbSNP Gene:27044 SND1
ENSEMBL:ENSG00000197157 SND1
ENSEMBL_homo_sapiens_GENE:ENSG00000197157.11 SND1
HGNC:30646 SND1
KEGG Gene (Homo sapiens):27044 SND1
Monarch:27044 SND1
NCBI Gene:27044 SND1
OMIM:602181 SND1
UCSC:Q7KZF4 SND1
Reference Transcript
Other Identifiers
11722036_a_at
17051105
201622_PM_at
201622_at
27044
3022466
3022467
3022468
3022469
3022478
3022482
3022484
3022485
3022486
3022487
3022488
3022489
3022492
3022521
3022532
3022544
3022553
3022561
3022586
3022651
3022663
3022666
3022667
3022670
3022671
3022674
3022677
3022679
3022680
3022681
3022682
37730_at
8135876
A_14_P111044
A_23_P42829
GE59012
GO:0001649
GO:0003676
GO:0003712
GO:0003723
GO:0003824
GO:0004518
GO:0004519
GO:0004521
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0006402
GO:0010564
GO:0010587
GO:0016020
GO:0016071
GO:0016442
GO:0016787
GO:0016894
GO:0030154
GO:0031047
GO:0031410
GO:0042470
GO:0043226
GO:0045296
GO:0070062
GO:0097433
GO:0140098
GO:0140110
GO:1905172
HMNXSV003048344
ILMN_1775111
PH_hs_0026601
TC07000764.hg
TC07002567.hg
U22055_at
g7657430_3p_at
g7657430_3p_x_at
Participates
as a component of
Other forms of this molecule
SND1(1-593)-p-BRAF(381-766) fusion [cytosol]
Modified Residues
Name
Insertion of residues 381 to 766 at 594 from UniProt:P15056 BRAF
Coordinate
594
Name
O-phospho-L-serine at 446
Coordinate
446
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 729
Coordinate
729
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Disease
Name Identifier Synonyms
gastric adenocarcinoma DOID:3717 adenocarcinoma of stomach (disorder), stomach adenocarcinoma
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Cross References
RefSeq
OpenTargets
IntEnz
HPA
GeneCards
Ensembl
PRO
Pharos - Targets
PDB
Interactors (2)
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