Reactome | DCD(20-110) [extracellular region]

DCD(20-110) [extracellular region]

Stable Identifier

R-HSA-6802997

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

DCD, AIDD, DSEP, Dermcidin

Locations in the PathwayBrowser for interactor UniProt:Q00005 2ABB

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External Reference Information

External Reference

UniProt:P81605 DCD

Gene Names

DCD, AIDD, DSEP

Chain

signal peptide:1-19, chain:20-110, peptide:20-49, propeptide:50-62, peptide:63-109, propeptide:-

Reference Genes

BioGPS Gene:117159 DCD

COSMIC (genes):DCD DCD

CTD Gene:117159 DCD

dbSNP Gene:117159 DCD

ENSEMBL:ENSG00000161634 DCD

ENSEMBL_homo_sapiens_GENE:ENSG00000161634.12 DCD

HGNC:14669 DCD

KEGG Gene (Homo sapiens):117159 DCD

Monarch:117159 DCD

NCBI Gene:117159 DCD

OMIM:606634 DCD

UCSC:P81605 DCD

Reference Transcript

Other Identifiers

117159

11751775_a_at

1553946_PM_at

1553946_at

16765648

3456897

3456898

3456899

3456900

3456901

3456902

3456903

3456904

3456905

3456907

7963845

A_23_P76218

GE535914

GO:0003723

GO:0003824

GO:0005215

GO:0005216

GO:0005515

GO:0005576

GO:0005615

GO:0006508

GO:0008233

GO:0008289

GO:0016020

GO:0016787

GO:0031640

GO:0034220

GO:0042742

GO:0043226

GO:0046872

GO:0050832

GO:0051873

GO:0055085

GO:0070062

GO:0098542

GO:0140096

HMNXSV003020496

Hs2.350570.1.S1_3p_at

ILMN_1722554

PH_hs_0027388

TC12001577.hg

Participates

as an input of

DCD is processed into DCD(63-110) (Homo sapiens)

Other forms of this molecule

DCD(20-62) [extracellular region]

DCD(63-110) [extracellular region]

DCD(63-109) [extracellular region]

Cross References

RefSeq

NP_001287783.1, NP_444513.1

OpenTargets

ENSG00000161634

GeneCards

P81605

HPA

ENSG00000161634-DCD

Ensembl

ENSP00000450415, ENST00000456047, ENST00000293371, ENSP00000293371, ENSP00000406773, ENST00000546807, ENSG00000161634

PRO

P81605

Pharos - Targets

P81605

HMDB Protein

HMDBP08838

PDB

6SHK, 2KSG, 2NDK, 2YMK

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P21796 VDAC1	7	PolyUb-VDAC1 [mitochondrial outer membrane] (R-HSA-6783079) VDAC1 [mitochondrial intermembrane space] (R-HSA-1267960) VDAC1 [mitochondrial outer membrane] (R-HSA-1267988) Ub-VDAC1 [mitochondrial outer membrane] (R-HSA-9834989) K48polyUb-VDAC1 [mitochondrial outer membrane] (R-HSA-5205624) K63polyUb-VDAC1 [mitochondrial outer membrane] (R-HSA-9834037) p-S65-Ub:VDAC1 [mitochondrial outer membrane] (R-HSA-9834991)	0.564	2
UniProt:Q92624 APBP2			0.556	3
UniProt:Q12797-6 ASPH			0.556	3
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	4
UniProt:Q00005 2ABB			0.462	2

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