Reactome | PGAM1 [ficolin-1-rich granule lumen]

PGAM1 [ficolin-1-rich granule lumen]

Stable Identifier

R-HSA-6803309

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

ficolin-1-rich granule lumen

Synonyms

phosphoglycerate mutase 1, bisphosphoglycerate mutase, bisphosphoglycerate phosphatase 1, Phosphoglycerate mutase 1 , Phosphoglycerate mutase isozyme B, PGAM-B, BPG-dependent PGAM 1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P18669 PGAM1

Gene Names

PGAM1, PGAMA, CDABP0006

Chain

initiator methionine:, chain:2-254

Reference Genes

BioGPS Gene:5223 PGAM1

COSMIC (genes):PGAM1 PGAM1

CTD Gene:5223 PGAM1

dbSNP Gene:5223 PGAM1

ENSEMBL:ENSG00000171314 PGAM1

HGNC:8888 PGAM1

KEGG:hsa:5223 PGAM1

Monarch:5223 PGAM1

NCBI Gene:5223 PGAM1

OMIM:172250 PGAM1

UCSC:P18669 PGAM1

Reference Transcript

RefSeq:NM_002629.3 PGAM1

Other Identifiers

11720915_x_at

11750286_x_at

11750438_x_at

11758691_x_at

16707970

200886_PM_s_at

200886_s_at

3259818

3259819

3259820

3259822

3259823

3259825

3259826

3259828

3259829

3259831

3259832

3259833

3377513

3377514

3429393

3429394

3429395

3429396

3429397

3429398

3429399

3465907

3465908

3465909

3465910

3465911

3465912

3465913

3465914

4013423

4013425

4013426

4013427

4056164

4056166

4056168

4056169

41221_at

5223

68315_at

7929624

7958152

7965480

8173729

8176282

A_32_P45738

A_33_P3268334

GE57505

GO:0003824

GO:0004082

GO:0004619

GO:0005515

GO:0005576

GO:0005737

GO:0005829

GO:0005975

GO:0006091

GO:0006094

GO:0006096

GO:0016020

GO:0016787

GO:0016853

GO:0016868

GO:0019901

GO:0034774

GO:0043226

GO:0046538

GO:0055086

GO:0061621

GO:0070062

GO:1901135

GO:1904813

HMNXSV003020829

ILMN_1661366

ILMN_2112417

J04173_at

PH_hs_0030347

TC10000695.hg

TC12000806.hg

g4505752_3p_a_at

Participates

as a member of

Ficolin-rich granule lumen proteins [ficolin-1-rich granule lumen] (Homo sapiens)

Other forms of this molecule

PGAM1 [cytosol]

PGAM1 [secretory granule lumen]

PGAM1 [extracellular region]

Inferred To

PGAM1 [ficolin-1-rich granule lumen] (Bos taurus)

PGAM1 [ficolin-1-rich granule lumen] (Canis familiaris)

PGAM1 [ficolin-1-rich granule lumen] (Danio rerio)

PGAM1 [ficolin-1-rich granule lumen] (Dictyostelium discoideum)

PGAM1 [ficolin-1-rich granule lumen] (Drosophila melanogaster)

PGAM1 [ficolin-1-rich granule lumen] (Gallus gallus)

PGAM1 [ficolin-1-rich granule lumen] (Mus musculus)

PGAM1 [ficolin-1-rich granule lumen] (Plasmodium falciparum)

PGAM1 [ficolin-1-rich granule lumen] (Rattus norvegicus)

PGAM1 [ficolin-1-rich granule lumen] (Schizosaccharomyces pombe)

PGAM1 [ficolin-1-rich granule lumen] (Sus scrofa)

PGAM1 [ficolin-1-rich granule lumen] (Xenopus tropicalis)

Cross References

RefSeq

NP_002620.1

OpenTargets

ENSG00000171314

ENSEMBL

ENST00000334828, ENSP00000359991

HPA

ENSG00000171314-PGAM1

ZINC - Substances

PGAM1_HUMAN

ZINC target

P18669

PRO

P18669

Pharos - Targets

P18669

GlyGen

P18669

PDB

8ITC, 5ZRM, 5Y64, 5ZS8, 8ITD, 5Y65, 1YJX, 7XB9, 8IT6, 8IT4, 8IT5, 4GPI, 8IT7, 7XB7, 1YFK, 5Y2I, 5Y35, 6ISN, 5Y2U, 4GPZ, 8IT8, 7XB8, 8ITB

HMDB Protein

HMDBP00269

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P05067 APP	20	APP(672-713) [extracellular region] (R-HSA-879340) APP(672-711) [cytosol] (R-HSA-877188) APP(672-711) [extracellular region] (R-HSA-976740) APP [endoplasmic reticulum lumen] (R-HSA-8956696) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP(18-770) [endosome lumen] (R-HSA-5229077) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-687) [extracellular region] (R-HSA-9010033) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-770) [extracellular region] (R-HSA-49335) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136)	0.666	4
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.615	12
UniProt:P10636-8 MAPT	3	MAPT-8 [cytosol] (R-HSA-9619519) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400)	0.569	8
UniProt:P12004 PCNA	5	PCNA [nucleoplasm] (R-HSA-68439) MonoUb-K164-PCNA [nucleoplasm] (R-HSA-5651986) ISG-K164,ISG-K168-PCNA [nucleoplasm] (R-HSA-5653768) K63polyUb-K164-PCNA [nucleoplasm] (R-HSA-8943000) monoSUMO1-K164,K254,K-PCNA [nucleoplasm] (R-HSA-4615861)	0.544	2

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