Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
NME2 [ficolin-1-rich granule lumen]
Stable Identifier
R-HSA-6803324
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
ficolin-1-rich granule lumen
Synonyms
non-metastatic cells 2, protein (NM23B) expressed in, Nucleoside diphosphate kinase B, nm23-H2, Nucleoside diphosphate kinase B , NDK B, NDP kinase B, C-myc purine-binding transcription factor PUF
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of ficolin-rich granule lumen proteins (Homo sapiens)
Ficolin-rich granule lumen proteins [ficolin-1-rich granule lumen] (Homo sapiens)
NME2 [ficolin-1-rich granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P22392 NME2
Gene Names
NME2, NM23B
Chain
chain:1-152
Reference Genes
BioGPS Gene:4831 NME2
BioGPS Gene:654364 NME2
COSMIC (genes):NME2 NME2
CTD Gene:4831 NME2
CTD Gene:654364 NME2
dbSNP Gene:4831 NME2
dbSNP Gene:654364 NME2
ENSEMBL:ENSG00000243678 NME2
HGNC:7850 NME2
KEGG:hsa:4831 NME2
KEGG:hsa:654364 NME2
Monarch:4831 NME2
Monarch:654364 NME2
NCBI Gene:4831 NME2
NCBI Gene:654364 NME2
OMIM:156491 NME2
UCSC:P22392 NME2
Reference Transcript
RefSeq:NM_001018139.2 NME2
RefSeq:NM_001018137.2 NME2
RefSeq:NM_002512.3 NME2
RefSeq:NM_001018138.1 NME2
RefSeq:NM_001018136.2 NME2
Other Identifiers
11718294_s_at
1980_s_at
201268_PM_at
201268_at
33415_at
3434301
3434305
3434307
3726961
3726962
3726964
3726965
3726966
3726967
3726968
3726969
3726970
3726971
3726974
3726975
4831
8180386
8180387
8180388
8180389
A_14_P105391
A_23_P141405
GE61684
GO:0001726
GO:0003677
GO:0003713
GO:0003824
GO:0004550
GO:0004673
GO:0005515
GO:0005524
GO:0005576
GO:0005634
GO:0005737
GO:0005829
GO:0006183
GO:0006228
GO:0006241
GO:0006355
GO:0007155
GO:0007229
GO:0009117
GO:0009142
GO:0016301
GO:0016740
GO:0019003
GO:0030027
GO:0034774
GO:0042802
GO:0042981
GO:0042995
GO:0043066
GO:0043226
GO:0045618
GO:0045682
GO:0045893
GO:0045944
GO:0046872
GO:0048471
GO:0050679
GO:0051880
GO:0055086
GO:0060090
GO:0070062
GO:0071944
GO:0140096
GO:0140110
GO:1901135
GO:1904813
HMNXSV003052386
ILMN_1657884
ILMN_1662905
ILMN_1694012
ILMN_2234873
ILMN_2414007
TC17002881.hg
g4505408_3p_s_at
Participates
as a member of
Ficolin-rich granule lumen proteins [ficolin-1-rich granule lumen] (Homo sapiens)
Other forms of this molecule
NME2 [secretory granule lumen]
NME2 [extracellular region]
NME2 [cytosol]
Inferred To
NME2 [ficolin-1-rich granule lumen]
(Bos taurus)
NME2 [ficolin-1-rich granule lumen]
(Caenorhabditis elegans)
NME2 [ficolin-1-rich granule lumen]
(Canis familiaris)
NME2 [ficolin-1-rich granule lumen]
(Dictyostelium discoideum)
NME2 [ficolin-1-rich granule lumen]
(Drosophila melanogaster)
NME2 [ficolin-1-rich granule lumen]
(Gallus gallus)
NME2 [ficolin-1-rich granule lumen]
(Mus musculus)
NME2 [ficolin-1-rich granule lumen]
(Plasmodium falciparum)
NME2 [ficolin-1-rich granule lumen]
(Rattus norvegicus)
NME2 [ficolin-1-rich granule lumen]
(Saccharomyces cerevisiae)
NME2 [ficolin-1-rich granule lumen]
(Schizosaccharomyces pombe)
NME2 [ficolin-1-rich granule lumen]
(Sus scrofa)
ndk-1 [ficolin-1-rich granule lumen]
(Caenorhabditis elegans)
nme2 [ficolin-1-rich granule lumen]
(Xenopus tropicalis)
nme2b.2 [ficolin-1-rich granule lumen]
(Danio rerio)
Homologues of NME2 [ficolin-1-rich granule lumen]
(Caenorhabditis elegans)
Homologues of NME2 [ficolin-1-rich granule lumen]
(Canis familiaris)
Homologues of NME2 [ficolin-1-rich granule lumen]
(Dictyostelium discoideum)
Cross References
OpenTargets
ENSG00000243678
ENSEMBL
ENST00000514264
,
ENST00000512737
,
ENST00000513177
,
ENSP00000426976
,
ENSP00000376886
,
ENST00000503064
,
ENSP00000426901
,
ENST00000393190
,
ENSP00000425581
,
ENSP00000421064
IntEnz
2.7.4.6
HPA
ENSG00000243678-NME2
ZINC - Substances
NDKB_HUMAN
ZINC target
P22392
PRO
P22392
Pharos - Targets
P22392
GlyGen
P22392
PDB
1NUE
,
3BBC
,
3BBB
,
1NSK
,
8PYW
,
3BBF
,
7KPF
HMDB Protein
HMDBP00112
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P50570 DNM2
5
DNM2 [Golgi membrane]
(R-HSA-2980842)
DNM2 [endocytic vesicle membrane]
(R-HSA-2029000)
DNM2 [cytosol]
(R-HSA-2213180)
DNM2 [lysosomal membrane]
(R-HSA-2980840)
DNM2 [plasma membrane]
(R-HSA-2984201)
0.525
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text