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capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm]
Stable Identifier
R-HSA-6803524
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by FGFR in disease (Homo sapiens)
Signaling by FGFR2 in disease (Homo sapiens)
FGFR2 mutant receptor activation (Homo sapiens)
Signaling by FGFR2 IIIa TM (Homo sapiens)
Aberrant alternative splicing yields a secreted FGFR2 IIIa TM disease variant (Homo sapiens)
capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by FGFR (Homo sapiens)
Signaling by FGFR2 (Homo sapiens)
FGFR2 alternative splicing (Homo sapiens)
ESRP1 and 2 bind FGFR2 pre-mRNA to promote FGFR2b maturation and expression (Homo sapiens)
FGFR2 IIIb-specific splicing complex [nucleoplasm] (Homo sapiens)
capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm] (Homo sapiens)
capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm] (Homo sapiens)
FGFR2b-specific alternative splicing produces FGFR2b transcript (Homo sapiens)
FGFR2 IIIb-specific splicing complex [nucleoplasm] (Homo sapiens)
capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm] (Homo sapiens)
FGFR2 IIIc-specific splicing complex [nucleoplasm] (Homo sapiens)
capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm] (Homo sapiens)
capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm] (Homo sapiens)
FGFR2c-specific alternative splicing produces FGFR2c transcript (Homo sapiens)
FGFR2 IIIb-specific splicing complex [nucleoplasm] (Homo sapiens)
capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm] (Homo sapiens)
FGFR2 IIIc-specific splicing complex [nucleoplasm] (Homo sapiens)
capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm] (Homo sapiens)
capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm] (Homo sapiens)
PTB and hnRNPA1 bind FGFR2 pre-mRNA to repress IIIb splicing and promote formation of FGFR2c mRNA (Homo sapiens)
FGFR2 IIIc-specific splicing complex [nucleoplasm] (Homo sapiens)
capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm] (Homo sapiens)
capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm] (Homo sapiens)
Participants
components
Cap Binding Complex (CBC) [nucleoplasm]
(Homo sapiens)
capped, methylated FGFR2 nascent transcript [nucleoplasm]
(Homo sapiens)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm]
(Homo sapiens)
Participates
as an input of
Aberrant alternative splicing yields a secreted FGFR2 IIIa TM disease variant (Homo sapiens)
FGFR2b-specific alternative splicing produces FGFR2b transcript (Homo sapiens)
FGFR2c-specific alternative splicing produces FGFR2c transcript (Homo sapiens)
ESRP1 and 2 bind FGFR2 pre-mRNA to promote FGFR2b maturation and expression (Homo sapiens)
PTB and hnRNPA1 bind FGFR2 pre-mRNA to repress IIIb splicing and promote formation of FGFR2c mRNA (Homo sapiens)
as a component of
FGFR2 IIIb-specific splicing complex [nucleoplasm] (Homo sapiens)
FGFR2 IIIc-specific splicing complex [nucleoplasm] (Homo sapiens)
Inferred To
capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm]
(Bos taurus)
capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm]
(Caenorhabditis elegans)
capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm]
(Canis familiaris)
capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm]
(Dictyostelium discoideum)
capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm]
(Drosophila melanogaster)
capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm]
(Gallus gallus)
capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm]
(Mus musculus)
capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm]
(Plasmodium falciparum)
capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm]
(Rattus norvegicus)
capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm]
(Saccharomyces cerevisiae)
capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm]
(Schizosaccharomyces pombe)
capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm]
(Sus scrofa)
capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm]
(Xenopus tropicalis)
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