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IQGAP2 [plasma membrane]
Stable Identifier
R-HSA-6804811
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Ras GTPase-activating-like protein IQGAP2
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of secretory granule membrane proteins (Homo sapiens)
Secretory granule membrane proteins [plasma membrane] (Homo sapiens)
IQGAP2 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13576 IQGAP2
Gene Names
IQGAP2
Chain
chain:1-1575
Reference Genes
BioGPS Gene:10788 IQGAP2
COSMIC (genes):IQGAP2 IQGAP2
CTD Gene:10788 IQGAP2
dbSNP Gene:10788 IQGAP2
ENSEMBL:ENSG00000145703 IQGAP2
HGNC:6111 IQGAP2
KEGG:hsa:10788 IQGAP2
Monarch:10788 IQGAP2
NCBI Gene:10788 IQGAP2
OMIM:605401 IQGAP2
UCSC:Q13576 IQGAP2
Reference Transcript
RefSeq:NM_001285460.1 IQGAP2
RefSeq:NM_006633.3 IQGAP2
RefSeq:NM_001285461.1 IQGAP2
RefSeq:NM_001285462.1 IQGAP2
Other Identifiers
10788
11721061_a_at
11745509_a_at
11747354_a_at
11758225_s_at
1647_at
16986351
203474_PM_at
203474_at
2816299
2816300
2816301
2816312
2816336
2816339
2816341
2816346
2816347
2816348
2816350
2816351
2816353
2816354
2816356
2816357
2816358
2816359
2816364
2816365
2816366
2816367
2816369
2816372
2816378
2816380
2816381
2816383
2816385
2816386
2816387
2816389
2816390
2816391
2816392
2816393
2816394
2816395
2816396
2816397
2816398
2816400
2816401
2816402
2816405
2816406
2816408
2816409
2816410
2816411
2816413
2816414
2816415
2816416
2816418
2816419
2816421
2816424
2816426
2816427
2816428
2816429
37276_at
47188_at
68641_at
8106354
A_14_P107921
A_14_P131808
A_24_P246361
A_33_P3216372
GE591714
GE59222
GO:0003779
GO:0005095
GO:0005096
GO:0005515
GO:0005516
GO:0005547
GO:0005737
GO:0005829
GO:0005856
GO:0005874
GO:0005886
GO:0005902
GO:0005938
GO:0007165
GO:0008092
GO:0008289
GO:0009986
GO:0015629
GO:0016020
GO:0030027
GO:0030175
GO:0030667
GO:0031267
GO:0032956
GO:0034314
GO:0043087
GO:0043226
GO:0051015
GO:0070062
GO:0070493
GO:0071933
GO:0098772
GO:0120025
GO:1903479
HMNXSV003014487
ILMN_1769433
PH_hs_0024229
TC05000368.hg
U51903_at
g5729886_3p_at
Participates
as a member of
Secretory granule membrane proteins [plasma membrane] (Homo sapiens)
Other forms of this molecule
IQGAP2 [secretory granule membrane]
IQGAP2 [cytosol]
Inferred To
IQGAP2 [plasma membrane]
(Bos taurus)
IQGAP2 [plasma membrane]
(Canis familiaris)
IQGAP2 [plasma membrane]
(Gallus gallus)
IQGAP2 [plasma membrane]
(Sus scrofa)
iqgap2 [plasma membrane]
(Xenopus tropicalis)
Iqgap2 [plasma membrane]
(Mus musculus)
Iqgap2 [plasma membrane]
(Rattus norvegicus)
pes-7 [plasma membrane]
(Caenorhabditis elegans)
rgaA [plasma membrane]
(Dictyostelium discoideum)
rng2 [plasma membrane]
(Schizosaccharomyces pombe)
IQG1 [plasma membrane]
(Saccharomyces cerevisiae)
Cross References
RefSeq
NP_001272390.1
,
NP_001272391.1
,
NP_001272389.1
,
NP_006624.2
ENSEMBL
ENSP00000274364
,
ENSP00000379535
,
ENST00000502745
,
ENSP00000426027
,
ENST00000274364
,
ENST00000396234
OpenTargets
ENSG00000145703
HPA
ENSG00000145703-IQGAP2
PRO
Q13576
Pharos - Targets
Q13576
GlyGen
Q13576
PDB
4EZA
,
5CJP
,
3IEZ
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P60953 CDC42
3
CDC42 [cytosol]
(R-HSA-442630)
CDC42 [plasma membrane]
(R-HSA-449545)
CDC42 [endoplasmic reticulum membrane]
(R-HSA-5672086)
0.688
4
UniProt:P63000 RAC1
6
RAC1 [plasma membrane]
(R-HSA-351141)
RAC1 [cytosol]
(R-HSA-442615)
GGC-PalmC-RAC1 [plasma membrane]
(R-HSA-2316446)
RAC1 [ficolin-1-rich granule membrane]
(R-HSA-6804802)
RAC1 [secretory granule membrane]
(R-HSA-6804770)
RAC1 [endoplasmic reticulum membrane]
(R-HSA-5672076)
0.638
3
UniProt:P01106 MYC
2
MYC [nucleoplasm]
(R-HSA-188379)
PolyUb-MYC [nucleoplasm]
(R-HSA-6783169)
0.564
2
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