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GPR84 [plasma membrane]
Stable Identifier
R-HSA-6805231
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
G-protein coupled receptor 84, GPR84_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of specific granule membrane proteins (Homo sapiens)
Specific granule membrane proteins [plasma membrane] (Homo sapiens)
GPR84 [plasma membrane] (Homo sapiens)
Exocytosis of tertiary granule membrane proteins (Homo sapiens)
Tertiary granule membrane proteins [plasma membrane] (Homo sapiens)
GPR84 [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (s) signalling events (Homo sapiens)
Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
Constitutively active orphan GPCRs [plasma membrane] (Homo sapiens)
GPR84 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
Constitutively active orphan GPCRs [plasma membrane] (Homo sapiens)
GPR84 [plasma membrane] (Homo sapiens)
Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
Constitutively active orphan GPCRs [plasma membrane] (Homo sapiens)
GPR84 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
Constitutively active orphan GPCRs [plasma membrane] (Homo sapiens)
GPR84 [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gs complex dissociates (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
Constitutively active orphan GPCRs [plasma membrane] (Homo sapiens)
GPR84 [plasma membrane] (Homo sapiens)
GPCRs that activate Gs [plasma membrane] (Homo sapiens)
Constitutively active orphan GPCRs [plasma membrane] (Homo sapiens)
GPR84 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NQS5 GPR84
Gene Names
GPR84, EX33
Chain
chain:1-396
Reference Genes
BioGPS Gene:53831 GPR84
COSMIC (genes):GPR84 GPR84
CTD Gene:53831 GPR84
dbSNP Gene:53831 GPR84
ENSEMBL:ENSG00000139572 GPR84
ENSEMBL_homo_sapiens_GENE:ENSG00000139572.4 GPR84
HGNC:4535 GPR84
KEGG Gene (Homo sapiens):53831 GPR84
Monarch:53831 GPR84
NCBI Gene:53831 GPR84
OMIM:606383 GPR84
UCSC:Q9NQS5 GPR84
Reference Transcript
RefSeq:XM_011538495.2 GPR84
RefSeq:NM_020370.2 GPR84
Other Identifiers
11737911_a_at
16765537
223767_PM_at
223767_at
3456689
3456690
3456691
3456692
3456693
3456694
3456696
3456697
53831
7963770
80657_at
A_23_P25155
GE79252
GO:0001604
GO:0004930
GO:0005886
GO:0007165
GO:0007186
GO:0007218
GO:0008150
GO:0016020
GO:0023052
GO:0031410
GO:0035579
GO:0043226
GO:0043235
GO:0060089
GO:0070821
HMNXSV003034989
ILMN_1785345
PH_hs_0015724
TC12001569.hg
g12711470_3p_at
Participates
as a member of
Specific granule membrane proteins [plasma membrane] (Homo sapiens)
Tertiary granule membrane proteins [plasma membrane] (Homo sapiens)
Constitutively active orphan GPCRs [plasma membrane] (Homo sapiens)
Other forms of this molecule
GPR84 [specific granule membrane]
GPR84 [tertiary granule membrane]
Inferred To
GPR84 [plasma membrane]
(Bos taurus)
GPR84 [plasma membrane]
(Canis familiaris)
GPR84 [plasma membrane]
(Sus scrofa)
AstA-R2 [plasma membrane]
(Drosophila melanogaster)
npr-14 [plasma membrane]
(Caenorhabditis elegans)
Homologues of GPR84 [plasma membrane]
(Drosophila melanogaster)
CG 13579 [plasma membrane]
(Drosophila melanogaster)
gpr84 [plasma membrane]
(Xenopus tropicalis)
Gpr84 [plasma membrane]
(Mus musculus)
Gpr84 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
XP_011536797.1
,
NP_065103.1
Guide to Pharmacology - Targets
120
OpenTargets
ENSG00000139572
GeneCards
Q9NQS5
HPA
ENSG00000139572-GPR84
Ensembl
ENST00000267015
,
ENST00000551809
,
ENSG00000139572
,
ENSP00000267015
,
ENSP00000450310
PRO
Q9NQS5
Pharos - Targets
Q9NQS5
PDB
8J1A
,
8G05
,
8J18
,
8J19
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