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TNFRSF1B [specific granule membrane]
Stable Identifier
R-HSA-6806149
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
specific granule membrane
Synonyms
Tumor necrosis factor receptor superfamily member 1B, TNR1B_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of specific granule membrane proteins (Homo sapiens)
Specific granule membrane proteins [specific granule membrane] (Homo sapiens)
TNFRSF1B [specific granule membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P20333 TNFRSF1B
Gene Names
TNFRSF1B, TNFBR, TNFR2
Chain
signal peptide:1-22, chain:23-461, chain:27-
Reference Genes
BioGPS Gene:7133 TNFRSF1B
COSMIC (genes):TNFRSF1B TNFRSF1B
CTD Gene:7133 TNFRSF1B
dbSNP Gene:7133 TNFRSF1B
ENSEMBL:ENSG00000028137 TNFRSF1B
HGNC:11917 TNFRSF1B
KEGG:hsa:7133 TNFRSF1B
Monarch:7133 TNFRSF1B
NCBI Gene:7133 TNFRSF1B
OMIM:191191 TNFRSF1B
UCSC:P20333 TNFRSF1B
Reference Transcript
RefSeq:NM_001066.2 TNFRSF1B
Other Identifiers
11718807_at
11753025_a_at
11755013_x_at
1583_at
16659238
17125970
203508_PM_at
203508_at
2320728
2320729
2320735
2320736
2320737
2320738
2320739
2320740
2320741
2320742
2320743
2320744
2320745
2320749
2320751
2320752
2320753
2320754
2320755
2320756
2320757
33813_at
7133
7896721
7897877
A_14_P200780
A_24_P54174
A_33_P3322274
GE57933
GO:0002376
GO:0002718
GO:0002724
GO:0002947
GO:0003176
GO:0003177
GO:0003332
GO:0005031
GO:0005515
GO:0005576
GO:0005886
GO:0006915
GO:0006954
GO:0006955
GO:0007166
GO:0008630
GO:0010614
GO:0012501
GO:0016020
GO:0023052
GO:0030424
GO:0031625
GO:0031641
GO:0031643
GO:0032496
GO:0033209
GO:0035579
GO:0042129
GO:0043025
GO:0043120
GO:0043196
GO:0045121
GO:0048471
GO:0048714
GO:0048856
GO:0050728
GO:0050779
GO:0051044
GO:0060089
GO:0071222
GO:0071356
GO:0071363
GO:0097191
GO:0150077
GO:0150079
GO:0150098
GO:1902339
HMNXSV003007792
HMNXSV003033485
HMNXSV003037451
ILMN_1764788
M32315_at
PH_hs_0013490
PH_hs_0032350
TC01000155.hg
g4507576_3p_at
g4507576_3p_x_at
Participates
as a member of
Specific granule membrane proteins [specific granule membrane] (Homo sapiens)
Other forms of this molecule
TNFRSF1B(27-?) [plasma membrane]
TNFRSF1B [plasma membrane]
Inferred To
Tnfrsf1b [specific granule membrane]
(Mus musculus)
Tnfrsf1b [specific granule membrane]
(Rattus norvegicus)
TNFRSF1B [specific granule membrane]
(Bos taurus)
TNFRSF1B [specific granule membrane]
(Canis familiaris)
TNFRSF1B [specific granule membrane]
(Gallus gallus)
TNFRSF1B [specific granule membrane]
(Sus scrofa)
Cross References
RefSeq
NP_001057.1
Guide to Pharmacology - Targets
1871
ENSEMBL
ENST00000376259
,
ENSP00000365435
OpenTargets
ENSG00000028137
HPA
ENSG00000028137-TNFRSF1B
PRO
P20333
Pharos - Targets
P20333
GlyGen
P20333
Orphanet
TNFRSF1B
PDB
1CA9
,
3ALQ
,
8HLB
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q12933 TRAF2
5
TRAF2 [cytosol]
(R-HSA-66370)
PolyUb-TRAF2 [cytosol]
(R-HSA-6782848)
K63polyUb-TRAF2 [cytosol]
(R-HSA-8862193)
K63polyUb-TRAF2 [nucleoplasm]
(R-HSA-8862194)
TRAF2 [nucleoplasm]
(R-HSA-8862199)
0.678
4
UniProt:P28799 GRN
2
GRN [azurophil granule lumen]
(R-HSA-6799168)
GRN [extracellular region]
(R-HSA-6806217)
0.644
5
UniProt:P01375 TNF
5
TNF(1-233) [plasma membrane]
(R-HSA-66220)
TNF(77-233) [extracellular region]
(R-HSA-976821)
TNF(1-76) [plasma membrane]
(R-HSA-8863120)
TNF(1-34) [plasma membrane]
(R-HSA-8863367)
TNF(52-76) [extracellular region]
(R-HSA-8863375)
0.609
2
UniProt:Q9NQH7 XPP3
0.564
2
UniProt:P11182 DBT
11
Lipo-K105-DBT [mitochondrial matrix]
(R-HSA-70017)
Isobutyryl-lipoH2-K105-DBT [mitochondrial matrix]
(R-HSA-9859151)
Isovaleryl-lipoH2-K105-DBT [mitochondrial matrix]
(R-HSA-9859144)
2-Methylbutyryl-lipoH2-K105-DBT [mitochondrial matrix]
(R-HSA-9859145)
LipoH2-K105-DBT [mitochondrial matrix]
(R-HSA-9859167)
DBT [mitochondrial matrix]
(R-HSA-6792584)
P276C Lipo-K105-DBT [mitochondrial matrix]
(R-HSA-9865046)
S399C Lipo-K105-DBT [mitochondrial matrix]
(R-HSA-9865036)
K313_Y338del Lipo-K105-DBT [mitochondrial matrix]
(R-HSA-9865051)
I98M Lipo-K105-DBT [mitochondrial matrix]
(R-HSA-9865057)
DBT [cytosol]
(R-HSA-9714663)
0.564
2
UniProt:Q13077 TRAF1
3
TRAF1 [cytosol]
(R-HSA-5634163)
TRAF1(1-163) [cytosol]
(R-HSA-5634199)
TRAF1(164-416) [cytosol]
(R-HSA-5634204)
0.547
2
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