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ORMDL3 [plasma membrane]
Stable Identifier
R-HSA-6806293
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
ORM1-like protein 3, ORML3_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of secretory granule membrane proteins (Homo sapiens)
Secretory granule membrane proteins [plasma membrane] (Homo sapiens)
ORMDL3 [plasma membrane] (Homo sapiens)
Exocytosis of specific granule membrane proteins (Homo sapiens)
Specific granule membrane proteins [plasma membrane] (Homo sapiens)
ORMDL3 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8N138 ORMDL3
Gene Names
ORMDL3
Chain
chain:1-153
Reference Genes
BioGPS Gene:94103 ORMDL3
COSMIC (genes):ORMDL3 ORMDL3
CTD Gene:94103 ORMDL3
dbSNP Gene:94103 ORMDL3
ENSEMBL:ENSG00000172057 ORMDL3
ENSEMBL_homo_sapiens_GENE:ENSG00000172057.10 ORMDL3
HGNC:16038 ORMDL3
KEGG Gene (Homo sapiens):94103 ORMDL3
Monarch:94103 ORMDL3
NCBI Gene:94103 ORMDL3
OMIM:610075 ORMDL3
UCSC:Q8N138 ORMDL3
Reference Transcript
RefSeq:NM_001320802.1 ORMDL3
RefSeq:XM_017025346.1 ORMDL3
RefSeq:NM_001320801.1 ORMDL3
RefSeq:NM_139280.3 ORMDL3
RefSeq:XM_017025348.1 ORMDL3
RefSeq:XM_017025347.1 ORMDL3
RefSeq:NM_001320803.1 ORMDL3
Other Identifiers
11736188_a_at
11736189_a_at
16844239
223259_PM_at
223259_at
235136_PM_at
235136_at
240701_PM_at
240701_at
3755931
3755933
3755935
3755936
3755937
3755938
3755939
3755940
3755941
3755942
3755943
3755944
3755945
3755946
3755947
3755948
3755950
3755951
65146_at
78377_at
8014916
94103
A_23_P129829
A_23_P38190
GE54915
GO:0002903
GO:0003012
GO:0005515
GO:0005783
GO:0005789
GO:0005886
GO:0006629
GO:0006672
GO:0006686
GO:0006914
GO:0006940
GO:0010508
GO:0012501
GO:0016020
GO:0030148
GO:0030667
GO:0031410
GO:0035339
GO:0035579
GO:0042552
GO:0043226
GO:0044255
GO:0048856
GO:0061744
GO:0090153
GO:0090156
GO:1900060
GO:1900182
GO:2000303
HMNXSV003026187
Hs.133167.0.A1_3p_at
Hs.293711.0.A1_3p_at
ILMN_1662174
PH_hs_0022499
PH_hs_0031753
TC17002852.hg
g12653706_3p_at
g12653706_3p_x_at
Participates
as a member of
Specific granule membrane proteins [plasma membrane] (Homo sapiens)
Secretory granule membrane proteins [plasma membrane] (Homo sapiens)
Other forms of this molecule
ORMDL3 [specific granule membrane]
ORMDL3 [secretory granule membrane]
ORMDL3 [endoplasmic reticulum membrane]
Inferred To
Ormdl3 [plasma membrane]
(Mus musculus)
Ormdl3 [plasma membrane]
(Rattus norvegicus)
ORM1 [plasma membrane]
(Saccharomyces cerevisiae)
ormdl3 [plasma membrane]
(Danio rerio)
ORM2 [plasma membrane]
(Saccharomyces cerevisiae)
Homologues of ORMDL3 [plasma membrane]
(Saccharomyces cerevisiae)
ORMDL3 [plasma membrane]
(Bos taurus)
ORMDL3 [plasma membrane]
(Canis familiaris)
ORMDL3 [plasma membrane]
(Dictyostelium discoideum)
ORMDL3 [plasma membrane]
(Gallus gallus)
ORMDL3 [plasma membrane]
(Schizosaccharomyces pombe)
ORMDL3 [plasma membrane]
(Sus scrofa)
ORMDL [plasma membrane]
(Drosophila melanogaster)
Cross References
RefSeq
NP_644809.1
,
XP_016880837.1
,
XP_016880836.1
,
NP_001307731.1
,
XP_016880835.1
,
NP_001307730.1
,
NP_001307732.1
OpenTargets
ENSG00000172057
HPA
ENSG00000172057-ORMDL3
GeneCards
Q8N138
Ensembl
ENST00000579695
,
ENSG00000172057
,
ENST00000584220
,
ENST00000304046
,
ENSP00000377724
,
ENSP00000464455
,
ENSP00000304858
,
ENST00000394169
,
ENSP00000464693
PRO
Q8N138
Pharos - Targets
Q8N138
PDB
7K0Q
,
7YIU
,
7K0P
,
7YJ1
,
7YIY
,
7K0M
,
7K0N
,
7YJ2
,
7CQI
,
6M4N
,
7CQK
,
6M4O
,
7K0O
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q7Z5P4 HSD17B13
1
HSD17B13 [cytosol]
(R-HSA-8862029)
0.556
3
UniProt:Q9H2K0 MTIF3
1
MTIF3 [mitochondrial matrix]
(R-HSA-5368284)
0.556
3
UniProt:P30825 SLC7A1
1
SLC7A1 [plasma membrane]
(R-HSA-375771)
0.556
3
UniProt:Q15125 EBP
1
EBP [endoplasmic reticulum membrane]
(R-HSA-195697)
0.556
3
UniProt:Q3SXY8 ARL13B
8
PolyUb-Misfolded ARL13B [lysosomal lumen]
(R-HSA-9660004)
PolyUb-Misfolded ARL13B [cytosol]
(R-HSA-9641129)
Ub-Misfolded ARL13B [cytosol]
(R-HSA-9641119)
Misfolded ARL13B [cytosol]
(R-HSA-9640110)
Misfolded ARL13B [cilium]
(R-HSA-9640116)
ARL13B [cilium]
(R-HSA-5618181)
PolyUb-Misfolded ARL13B [late endosome lumen]
(R-HSA-9659986)
ARL13B [plasma membrane]
(R-HSA-9716787)
0.556
3
UniProt:Q14973 SLC10A1
1
SLC10A1 [plasma membrane]
(R-HSA-194116)
0.556
3
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