Reactome | CNN2 [extracellular region]

CNN2 [extracellular region]

Stable Identifier

R-HSA-6806300

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Calponin-2, CNN2_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q99439 CNN2

Gene Names

CNN2, Calponin-2

Chain

initiator methionine:, chain:2-309

Reference Genes

BioGPS Gene:1265 CNN2

COSMIC (genes):CNN2 CNN2

CTD Gene:1265 CNN2

dbSNP Gene:1265 CNN2

ENSEMBL:ENSG00000064666 CNN2

ENSEMBL_homo_sapiens_GENE:ENSG00000064666.15 CNN2

HGNC:2156 CNN2

KEGG Gene (Homo sapiens):1265 CNN2

Monarch:1265 CNN2

NCBI Gene:1265 CNN2

OMIM:602373 CNN2

UCSC:Q99439 CNN2

Reference Transcript

Other Identifiers

11723414_a_at

11723415_s_at

11723416_x_at

11746548_s_at

11746549_x_at

11748403_x_at

11751244_s_at

11751245_x_at

11754644_x_at

1265

16856350

201605_PM_x_at

201605_x_at

2921292

3815401

3815402

3815403

3815405

3815406

3815407

3815409

3815410

3815411

3815412

3815413

3815414

3815415

3815417

8024111

A_23_P16673

A_24_P142743

D83735_at

GE57337

GE86648

GO:0001725

GO:0002376

GO:0003779

GO:0005515

GO:0005516

GO:0005576

GO:0005856

GO:0005911

GO:0005925

GO:0006909

GO:0007010

GO:0007015

GO:0008092

GO:0010628

GO:0015629

GO:0016020

GO:0016192

GO:0030097

GO:0030154

GO:0031032

GO:0031410

GO:0032970

GO:0035580

GO:0042060

GO:0043226

GO:0045296

GO:0048856

GO:0048870

GO:0050765

GO:0051015

GO:0051649

GO:0070663

GO:0071260

GO:1904724

GO:1905517

GO:1905522

HMNXSV003035979

HMNXSV003048101

ILMN_1708486

ILMN_1770290

PH_hs_0010116

TC19000027.hg

g4758017_3p_at

g4758017_3p_x_at

p33938

Participates

as an output of

Expression of calponin-2 (Homo sapiens)

as a member of

Other forms of this molecule

CNN2 [tertiary granule lumen]

CNN2 [specific granule lumen]

Inferred To

CNN2 [extracellular region] (Bos taurus)

CNN2 [extracellular region] (Canis familiaris)

CNN2 [extracellular region] (Dictyostelium discoideum)

CNN2 [extracellular region] (Gallus gallus)

CNN2 [extracellular region] (Sus scrofa)

SCP1 [extracellular region] (Saccharomyces cerevisiae)

Cnn2 [extracellular region] (Mus musculus)

Cnn2 [extracellular region] (Rattus norvegicus)

cnn2 [extracellular region] (Xenopus tropicalis)

Homologues of CNN2 [extracellular region] (Dictyostelium discoideum)

Cross References

RefSeq

NP_001290428.1, NP_958434.1, NP_004359.1, NP_001290430.1

OpenTargets

ENSG00000064666

HPA

ENSG00000064666-CNN2

GeneCards

Q99439

Ensembl

ENSP00000263097, ENST00000348419, ENSG00000064666, ENST00000263097, ENSP00000340129

PRO

Q99439

Pharos - Targets

Q99439

PDB

1WYN

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UJ70 NAGK	1	NAGK [cytosol] (R-HSA-6803742)	0.527	2
UniProt:Q15417 CNN3			0.527	3
UniProt:O95260 ATE1			0.527	3
UniProt:P11142 HSPA8	10	Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217) HSPA8 [secretory granule lumen] (R-HSA-6801530) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [cytosol] (R-HSA-264476)	0.527	2
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	6

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