Reactome | SNRNP27 [nucleoplasm]

SNRNP27 [nucleoplasm]

Stable Identifier

R-HSA-6806778

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein, SNR27_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q96A49 SYAP1

Expand all

External Reference Information

External Reference

UniProt:Q8WVK2 SNRNP27

Gene Names

SNRNP27

Chain

chain:1-155

Reference Genes

BioGPS Gene:11017 SNRNP27

COSMIC (genes):SNRNP27 SNRNP27

CTD Gene:11017 SNRNP27

dbSNP Gene:11017 SNRNP27

ENSEMBL:ENSG00000124380 SNRNP27

ENSEMBL_homo_sapiens_GENE:ENSG00000124380.11 SNRNP27

HGNC:30240 SNRNP27

KEGG Gene (Homo sapiens):11017 SNRNP27

Monarch:11017 SNRNP27

NCBI Gene:11017 SNRNP27

OMIM:619629 SNRNP27

UCSC:Q8WVK2 SNRNP27

Reference Transcript

RefSeq:NM_006857.2 SNRNP27

Other Identifiers

11017

11743659_a_at

11743660_x_at

16881119

212438_PM_at

212438_at

212440_PM_at

212440_at

2487528

2487529

2487530

2487531

2487532

2487534

2487536

2487537

2487538

2487539

2487540

2487541

2487542

2487543

2875628

2875630

35286_r_at

8042495

A_23_P39774

GE60018

GO:0000398

GO:0003676

GO:0005515

GO:0005575

GO:0005634

GO:0005654

GO:0006397

GO:0008150

GO:0008380

GO:0016071

GO:0043226

GO:0046540

HMNXSV003017151

Hs.54649.0.S1_3p_at

Hs.54649.0.S2_3p_at

ILMN_2069945

PH_hs_0003588

TC02003309.hg

TC02004969.hg

X76302_at

Participates

as an output of

Formation of the Spliceosomal B complex (Homo sapiens)

as a component of

U4:U5:U6 tri-snRNP complex [nucleoplasm] (Homo sapiens)

Inferred To

snrnp27 [nucleoplasm] (Xenopus tropicalis)

ytr [nucleoplasm] (Drosophila melanogaster)

SNRNP27 [nucleoplasm] (Bos taurus)

SNRNP27 [nucleoplasm] (Canis familiaris)

SNRNP27 [nucleoplasm] (Dictyostelium discoideum)

SNRNP27 [nucleoplasm] (Gallus gallus)

SNRNP27 [nucleoplasm] (Plasmodium falciparum)

SNRNP27 [nucleoplasm] (Schizosaccharomyces pombe)

SNRNP27 [nucleoplasm] (Sus scrofa)

Snrnp27 [nucleoplasm] (Mus musculus)

Snrnp27 [nucleoplasm] (Rattus norvegicus)

snrp-27 [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

NP_006848.1

OpenTargets

ENSG00000124380

HPA

ENSG00000124380-SNRNP27

GeneCards

Q8WVK2

Ensembl

ENSG00000124380, ENSP00000244227, ENST00000244227, ENST00000450162, ENSP00000395144

PRO

Q8WVK2

Pharos - Targets

Q8WVK2

PDB

6QW6, 6QX9

Interactors (56)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P78362 SRPK2	1	SRPK2 [cytosol] (R-HSA-9729332)	0.754	5
UniProt:Q9GZZ1 NAA50			0.527	2
UniProt:Q9H993 ARMT1			0.527	2
UniProt:Q05639 EEF1A2	1	EEF1A2 [cytosol] (R-HSA-3907261)	0.527	2
UniProt:Q9NQG5 RPRD1B	1	RPRD1B [nucleoplasm] (R-HSA-6814894)	0.527	2
UniProt:Q9UNH7 SNX6			0.527	2
UniProt:Q96ER9 MITOK			0.527	2
UniProt:P46063 RECQ1			0.527	2
UniProt:O43776 NARS1	1	NARS [cytosol] (R-HSA-379625)	0.527	2
UniProt:O95747 OXSR1			0.527	2
UniProt:Q9NPD8 UBE2T	3	UBE2T [nucleoplasm] (R-HSA-420942) MonoUb-K91,K182-UBE2T [nucleoplasm] (R-HSA-6785362) Ub-C86-UBE2T [nucleoplasm] (R-HSA-8864217)	0.527	2
UniProt:Q9H0C8 ILKAP			0.527	2
UniProt:Q96KB5 TOPK			0.527	2
UniProt:O43252 PAPSS1	3	PAPSS1 [cytosol] (R-HSA-174387) PAPSS1(1-223)-BRAF(381-766) fusion [cytosol] (R-HSA-6802432) PAPSS1(1-223)-p-BRAF(381-766) fusion [cytosol] (R-HSA-6802543)	0.527	2
UniProt:Q9Y6B6 SAR1B	3	SAR1B [ER to Golgi transport vesicle membrane] (R-HSA-211498) SAR1B [cytosol] (R-HSA-174678) SAR1B [endoplasmic reticulum membrane] (R-HSA-203995)	0.527	2
UniProt:P30043 BLVRB	1	BLVRB [cytosol] (R-HSA-189388)	0.527	2
UniProt:Q96DI7 SNRNP40	1	SNRNP40 [nucleoplasm] (R-HSA-71877)	0.527	2
UniProt:P62495 ETF1	3	Me-Q185-ETF1 [cytosol] (R-HSA-6800157) 4OHK63-ETF1 [cytosol] (R-HSA-9629948) ETF1 [cytosol] (R-HSA-54433)	0.527	2
UniProt:Q9NTZ6 RBM12			0.527	2
UniProt:Q86VZ2 WDR5B			0.527	2
UniProt:O43583 DENR			0.527	2
UniProt:Q6IN85 P4R3A			0.527	2
UniProt:Q9BXJ9 NAA15			0.527	2
UniProt:P82970 HMGN5			0.527	2
UniProt:Q9Y3A5 SBDS			0.527	2
UniProt:Q96P16 RPRD1A	1	RPRD1A [nucleoplasm] (R-HSA-6814899)	0.527	2
UniProt:P29144 TPP2	1	TPP2 [cytosol] (R-HSA-983068)	0.527	2
UniProt:Q9NUQ3 TXLNG			0.527	2
UniProt:O95202 LETM1	2	LETM1 [endoplasmic reticulum membrane] (R-HSA-9714759) LETM1 [mitochondrial inner membrane] (R-HSA-8949702)	0.527	2
UniProt:Q14847 LASP1			0.527	2
UniProt:Q96A49 SYAP1			0.527	2
UniProt:Q9BUL8 PDC10			0.527	2
UniProt:Q96FW1 OTUB1	2	OTUB1 [cytosol] (R-HSA-933411) OTUB1 [nucleoplasm] (R-HSA-6783242)	0.527	2
UniProt:O60493 SNX3	3	SNX3 [cytosol] (R-HSA-3247743) PolyUb-SNX3 [endosome membrane] (R-HSA-6782993) SNX3 [endosome membrane] (R-HSA-6782991)	0.527	2
UniProt:O43395 PRPF3	1	PRPF3 [nucleoplasm] (R-HSA-6806806)	0.527	2
UniProt:A0AVT1 UBA6	1	UBA6 [cytosol] (R-HSA-947701)	0.527	2
UniProt:Q99986 VRK1	2	VRK1 [nucleoplasm] (R-HSA-2528998) VRK1 [cytosol] (R-HSA-2995381)	0.527	2
UniProt:Q13177 PAK2	11	p-S141,T402-PAK2 [plasma membrane] (R-HSA-5096524) PAK2(1-524) [plasma membrane] (R-HSA-164946) p-Y130,S141,T402-PAK2 [cytosol] (R-HSA-5218705) K48polyUb-p-T402-PAK-2p43 [cytosol] (R-HSA-3095873) p-T402-PAK2(213-524) [nucleoplasm] (R-HSA-211709) p-T402-PAK2(213-524) [cytosol] (R-HSA-211654) p-5S-PAK2(2-212) [cytosol] (R-HSA-211588) p-S141,T402-PAK2 [cytosol] (R-HSA-399824) PAK2 [cytosol] (R-HSA-211604) p-5S-PAK2 [cytosol] (R-HSA-211609) PAK2(213-524) [cytosol] (R-HSA-211653)	0.527	2
UniProt:P62304 SNRPE	2	SNRPE [nucleoplasm] (R-HSA-71905) SNRPE [cytosol] (R-HSA-191782)	0.527	4
UniProt:Q15836 VAMP3	6	VAMP3 [recycling endosome membrane] (R-HSA-2029063) VAMP3 [phagocytic vesicle membrane] (R-HSA-2029013) VAMP3 [plasma membrane] (R-HSA-8867599) VAMP3 [trans-Golgi network membrane] (R-HSA-6814624) VAMP3 [transport vesicle] (R-HSA-6814625) VAMP3 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869130)	0.527	2
UniProt:Q9Y490 TLN1	2	TLN1 [extracellular region] (R-HSA-350693) TLN1 [cytosol] (R-HSA-350713)	0.527	2
UniProt:P27144 AK4	1	AK4 [mitochondrial matrix] (R-HSA-6788783)	0.527	2
UniProt:P39748 FEN1	1	FEN1 [nucleoplasm] (R-HSA-54745)	0.527	2
UniProt:Q00341 HDLBP	1	HDLBP [plasma membrane] (R-HSA-8858026)	0.527	2
UniProt:Q13526 PIN1	2	PIN1 [cytosol] (R-HSA-9626823) PIN1 [nucleoplasm] (R-HSA-936016)	0.527	2
UniProt:Q15126 PMVK	1	PMVK [cytosol] (R-HSA-191348)	0.527	2
UniProt:P27361 MAPK3	6	MAPK3 [endoplasmic reticulum lumen] (R-HSA-9636295) p-T202-MAPK3 [cytosol] (R-HSA-9635775) MAPK3 [nucleoplasm] (R-HSA-73724) MAPK3 [cytosol] (R-HSA-59284) p-T202,Y204-MAPK3 [cytosol] (R-HSA-109842) p-T202,Y204-MAPK3 [nucleoplasm] (R-HSA-112359)	0.527	2
UniProt:Q9Y2L1 DIS3	2	DIS3 [nucleoplasm] (R-HSA-6791517) DIS3 [cytosol] (R-HSA-429935)	0.527	2
UniProt:Q14651 PLS1	1	PLS1 [cytosol] (R-HSA-9662403)	0.527	2
UniProt:Q15785 TOM34			0.527	2
UniProt:Q9BY44 EIF2A			0.527	2
UniProt:P63162 SNRPN	1	Me2-R108,R112-SNRPN [nucleoplasm] (R-HSA-8865931)	0.527	2
UniProt:Q99584 S10AD			0.527	2
UniProt:P84085 ARF5	1	ARF5 [cytosol] (R-HSA-6807737)	0.527	2
UniProt:Q2TAL8 QRIC1			0.527	2
UniProt:Q8IWX8 CHERP	1	CHERP [nucleoplasm] (R-HSA-8865901)	0.508	2

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