Reactome | USP39 [nucleoplasm]

USP39 [nucleoplasm]

Stable Identifier

R-HSA-6806793

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

U4/U6.U5 tri-snRNP-associated protein 2, SNUT2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q53GS9 USP39

Gene Names

USP39, CGI-21, HSPC332, PRO2855

Chain

chain:1-565

Reference Genes

BioGPS Gene:10713 USP39

COSMIC (genes):USP39 USP39

CTD Gene:10713 USP39

dbSNP Gene:10713 USP39

ENSEMBL:ENSG00000168883 USP39

HGNC:20071 USP39

KEGG:hsa:10713 USP39

Monarch:10713 USP39

NCBI Entrez Gene:10713 USP39

OMIM:611594 USP39

UCSC:Q53GS9 USP39

Reference Transcript

Other Identifiers

10713

11716429_a_at

11744521_x_at

11747738_x_at

11749041_a_at

11754944_x_at

16882304

217829_PM_s_at

217829_s_at

2491703

2491708

2491709

2491710

2491711

2491713

2491714

2491715

2491716

2491717

2491718

2491719

2491720

2491721

2491722

2491723

2491726

2491727

2491728

2491729

2491730

2491731

2491733

2491734

2491735

2491736

2491737

2491738

2491740

48911_at

8043218

A_14_P127348

A_32_P101301

A_33_P3399840

GE61836

GO:0000245

GO:0000398

GO:0004843

GO:0005515

GO:0005634

GO:0005654

GO:0005681

GO:0006397

GO:0008270

GO:0008380

GO:0016071

GO:0016579

GO:0016787

GO:0046540

GO:0046872

GO:0051301

GO:0065003

HMNXSV003053359

ILMN_1659523

TC02000515.hg

g5730024_3p_a_at

Participates

as an output of

Formation of the Spliceosomal B complex (Homo sapiens)

as a component of

U4:U5:U6 tri-snRNP complex [nucleoplasm] (Homo sapiens)

Inferred To

Usp39 [nucleoplasm] (Drosophila melanogaster)

Usp39 [nucleoplasm] (Rattus norvegicus)

usp39 [nucleoplasm] (Dictyostelium discoideum)

usp39 [nucleoplasm] (Xenopus tropicalis)

USP39 [nucleoplasm] (Bos taurus)

USP39 [nucleoplasm] (Canis familiaris)

USP39 [nucleoplasm] (Mus musculus)

USP39 [nucleoplasm] (Plasmodium falciparum)

USP39 [nucleoplasm] (Schizosaccharomyces pombe)

USP39 [nucleoplasm] (Sus scrofa)

Ghost homologue of USP39 [nucleoplasm] (Gallus gallus)

usp-39 [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001243656.1, NP_001243655.1, XP_016858671.1, NP_001243657.1, XP_011530789.1, NP_006581.2, XP_006711985.1, XP_006711986.1, NP_001243654.1, XP_011530790.1

OpenTargets

ENSG00000168883

ENSEMBL

ENSG00000168883, ENSP00000386803, ENSP00000386864, ENST00000450066, ENST00000323701, ENSP00000312981, ENST00000409470, ENSP00000396133, ENST00000409766

HPA

ENSG00000168883-USP39

GeneCards

USP39

PRO

Q53GS9

Pharos - Targets

Q53GS9

GlyGen

Q53GS9

PDB

6AH0, 3JCR, 8H6E, 8H6J, 8R0B, 8R09, 8R0A, 8QPK, 6QW6, 8R08, 8RM5, 8QZS, 8QPE, 8QPB, 8QOZ, 8QXD, 6QX9, 8QPA, 8Y6O, 8QP9, 8QP8

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O95400 CD2BP2	1	CD2BP2 [nucleoplasm] (R-HSA-72054)	0.744	4
UniProt:Q13523 PRP4K	1	PRPF4B [nucleoplasm] (R-HSA-9769525)	0.643	3
UniProt:Q96DI7 SNRNP40	1	SNRNP40 [nucleoplasm] (R-HSA-71877)	0.643	3
UniProt:Q15029 EFTUD2	1	EFTUD2 [nucleoplasm] (R-HSA-71883)	0.615	3
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.59	3
UniProt:Q96SB4 SRPK1	2	SRPK1 [nucleoplasm] (R-HSA-9821984) SRPK1 [cytosol] (R-HSA-9729349)	0.59	2
UniProt:Q6P2Q9 PRPF8	1	PRPF8 [nucleoplasm] (R-HSA-83810)	0.527	2
UniProt:O43172 PRPF4	1	PRPF4 [nucleoplasm] (R-HSA-71890)	0.527	3
UniProt:O95218 ZRAB2			0.483	2

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