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BET1L [Golgi membrane]
Stable Identifier
R-HSA-6807744
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
GS15
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Transport to the Golgi and subsequent modification (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPI-mediated anterograde transport (Homo sapiens)
COPI vesicle uncoating (Homo sapiens)
RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Homo sapiens)
cis-Golgi t-SNARES [Golgi membrane] (Homo sapiens)
GOSR1:BET1L:STX5 [Golgi membrane] (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
cis-Golgi cis SNARE bundle [Golgi membrane] (Homo sapiens)
cis-Golgi t-SNARES [Golgi membrane] (Homo sapiens)
GOSR1:BET1L:STX5 [Golgi membrane] (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
NSF ATPase activity dissociates cis-SNARE at cis-Golgi (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
cis-SNARE:3xSNAP:NSF hexamer [Golgi membrane] (Homo sapiens)
cis-Golgi cis SNARE bundle [Golgi membrane] (Homo sapiens)
cis-Golgi t-SNARES [Golgi membrane] (Homo sapiens)
GOSR1:BET1L:STX5 [Golgi membrane] (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
cis-Golgi cis-SNARE binds NSF and SNAPs (Homo sapiens)
cis-Golgi cis SNARE bundle [Golgi membrane] (Homo sapiens)
cis-Golgi t-SNARES [Golgi membrane] (Homo sapiens)
GOSR1:BET1L:STX5 [Golgi membrane] (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
cis-SNARE:3xSNAP:NSF hexamer [Golgi membrane] (Homo sapiens)
cis-Golgi cis SNARE bundle [Golgi membrane] (Homo sapiens)
cis-Golgi t-SNARES [Golgi membrane] (Homo sapiens)
GOSR1:BET1L:STX5 [Golgi membrane] (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Homo sapiens)
RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Homo sapiens)
cis-Golgi t-SNARES [Golgi membrane] (Homo sapiens)
GOSR1:BET1L:STX5 [Golgi membrane] (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
cis-Golgi t-SNARES [Golgi membrane] (Homo sapiens)
GOSR1:BET1L:STX5 [Golgi membrane] (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPI-mediated anterograde transport (Homo sapiens)
COPI vesicle uncoating (Homo sapiens)
RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Homo sapiens)
cis-Golgi t-SNARES [Golgi membrane] (Homo sapiens)
GOSR1:BET1L:STX5 [Golgi membrane] (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
cis-Golgi cis SNARE bundle [Golgi membrane] (Homo sapiens)
cis-Golgi t-SNARES [Golgi membrane] (Homo sapiens)
GOSR1:BET1L:STX5 [Golgi membrane] (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
NSF ATPase activity dissociates cis-SNARE at cis-Golgi (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
cis-SNARE:3xSNAP:NSF hexamer [Golgi membrane] (Homo sapiens)
cis-Golgi cis SNARE bundle [Golgi membrane] (Homo sapiens)
cis-Golgi t-SNARES [Golgi membrane] (Homo sapiens)
GOSR1:BET1L:STX5 [Golgi membrane] (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
cis-Golgi cis-SNARE binds NSF and SNAPs (Homo sapiens)
cis-Golgi cis SNARE bundle [Golgi membrane] (Homo sapiens)
cis-Golgi t-SNARES [Golgi membrane] (Homo sapiens)
GOSR1:BET1L:STX5 [Golgi membrane] (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
cis-SNARE:3xSNAP:NSF hexamer [Golgi membrane] (Homo sapiens)
cis-Golgi cis SNARE bundle [Golgi membrane] (Homo sapiens)
cis-Golgi t-SNARES [Golgi membrane] (Homo sapiens)
GOSR1:BET1L:STX5 [Golgi membrane] (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Homo sapiens)
RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Homo sapiens)
cis-Golgi t-SNARES [Golgi membrane] (Homo sapiens)
GOSR1:BET1L:STX5 [Golgi membrane] (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
cis-Golgi t-SNARES [Golgi membrane] (Homo sapiens)
GOSR1:BET1L:STX5 [Golgi membrane] (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Intra-Golgi traffic (Homo sapiens)
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
STX5:PalmC-YKT6:BET1L:GOSR1:NSF hexamer:3xSNAPs [Golgi membrane] (Homo sapiens)
STX:PalmC-YKT6:BET1L:GOSR1 [Golgi membrane] (Homo sapiens)
STX5:PalmC-YKT6:BET1L [Golgi membrane] (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
Formation of cis-SNARE complex and membrane fusion in intra-Golgi retrograde traffic (Homo sapiens)
COG complex:CUX1 dimer:GOLGA5 dimer:STX5:PalmC-YKT6:BET1L:GOSR1:intra-Golgi retrograde cargo [Golgi membrane] (Homo sapiens)
STX5:PalmC-YKT6:BET1L [Golgi membrane] (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
STX:PalmC-YKT6:BET1L:GOSR1 [Golgi membrane] (Homo sapiens)
STX5:PalmC-YKT6:BET1L [Golgi membrane] (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
NSF and SNAPs bind the cis-SNARE at the Golgi (Homo sapiens)
STX5:PalmC-YKT6:BET1L:GOSR1:NSF hexamer:3xSNAPs [Golgi membrane] (Homo sapiens)
STX:PalmC-YKT6:BET1L:GOSR1 [Golgi membrane] (Homo sapiens)
STX5:PalmC-YKT6:BET1L [Golgi membrane] (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
STX:PalmC-YKT6:BET1L:GOSR1 [Golgi membrane] (Homo sapiens)
STX5:PalmC-YKT6:BET1L [Golgi membrane] (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
The COG complex and CUX1 and GOLGA5 dimers contribute to intra-Golgi vesicle tethering (Homo sapiens)
COG complex:CUX1 dimer:GOLGA5 dimer:STX5:PalmC-YKT6:BET1L:GOSR1:intra-Golgi retrograde cargo [Golgi membrane] (Homo sapiens)
STX5:PalmC-YKT6:BET1L [Golgi membrane] (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
STX5:PalmC-YKT6:BET1L [Golgi membrane] (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
The COG tethering complex interacts with numerous SNAREs at the Golgi membrane (Homo sapiens)
COG complex:Golgi snares [Golgi membrane] (Homo sapiens)
other COG interacting snares [Golgi membrane] (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
other COG interacting snares [Golgi membrane] (Homo sapiens)
BET1L [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NYM9 BET1L
Gene Names
BET1L, GS15
Chain
chain:1-111
Reference Genes
BioGPS Gene:51272 BET1L
COSMIC (genes):BET1L BET1L
CTD Gene:51272 BET1L
dbSNP Gene:51272 BET1L
ENSEMBL:ENSG00000177951 BET1L
HGNC:19348 BET1L
KEGG:hsa:51272 BET1L
Monarch:51272 BET1L
NCBI Gene:51272 BET1L
OMIM:615417 BET1L
UCSC:Q9NYM9 BET1L
Reference Transcript
RefSeq:NM_001098787.1 BET1L
Other Identifiers
11745186_a_at
11745187_a_at
11745188_a_at
16733808
17120642
220470_PM_at
220470_at
223023_PM_at
223023_at
2457495
2660101
3022923
3034739
3195803
3357726
3357732
3357734
3357735
3357736
3357737
3357738
3357739
3357740
3357741
3357742
3357743
3357744
3357745
3357746
3357747
3357748
3357749
3357750
3357751
3357752
3357753
3674705
3844456
3844458
4045090
45274_at
51272
74963_f_at
74964_at
7945349
87682_at
A_21_P0011501
A_23_P127879
A_24_P386639
A_33_P3225882
A_33_P3330384
GE54911
GO:0000139
GO:0005484
GO:0005515
GO:0005768
GO:0005794
GO:0005829
GO:0015031
GO:0016020
GO:0016192
GO:0031201
GO:0031410
GO:0042147
GO:0043226
GO:0060090
GO:0061024
GO:0061025
GO:2000156
HMNXSV003008394
HMNXSV003028436
HMNXSV003032638
HMNXSV003049220
ILMN_1789086
ILMN_2060652
PH_hs_0015469
TC11003513.hg
g12653798_3p_at
g7706072_3p_at
p33598
Participates
as a member of
other COG interacting snares [Golgi membrane] (Homo sapiens)
as an output of
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Homo sapiens)
NSF ATPase activity dissociates cis-SNARE at cis-Golgi (Homo sapiens)
as a component of
STX5:PalmC-YKT6:BET1L [Golgi membrane] (Homo sapiens)
GOSR1:BET1L:STX5 [Golgi membrane] (Homo sapiens)
Inferred To
Homologues of BET1L [Golgi membrane]
(Saccharomyces cerevisiae)
Homologues of BET1L [Golgi membrane]
(Schizosaccharomyces pombe)
SFT1 [Golgi membrane]
(Saccharomyces cerevisiae)
bet1l [Golgi membrane]
(Danio rerio)
bet1l [Golgi membrane]
(Xenopus tropicalis)
BET1L [Golgi membrane]
(Bos taurus)
BET1L [Golgi membrane]
(Canis familiaris)
BET1L [Golgi membrane]
(Dictyostelium discoideum)
BET1L [Golgi membrane]
(Gallus gallus)
BET1L [Golgi membrane]
(Sus scrofa)
Ghost homologue of BET1L [Golgi membrane]
(Caenorhabditis elegans)
Ghost homologue of BET1L [Golgi membrane]
(Drosophila melanogaster)
Ghost homologue of BET1L [Golgi membrane]
(Plasmodium falciparum)
bet1 [Golgi membrane]
(Schizosaccharomyces pombe)
BET1 [Golgi membrane]
(Saccharomyces cerevisiae)
sft1 [Golgi membrane]
(Schizosaccharomyces pombe)
Bet1l [Golgi membrane]
(Mus musculus)
Bet1l [Golgi membrane]
(Rattus norvegicus)
Cross References
ENSEMBL
ENST00000382762
,
ENSP00000372210
OpenTargets
ENSG00000177951
HPA
ENSG00000177951-BET1L
PRO
Q9NYM9
Pharos - Targets
Q9NYM9
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O95183 VAMP5
0.527
3
UniProt:Q9P2W9 STX18
1
STX18 [endoplasmic reticulum membrane]
(R-HSA-2029079)
0.527
3
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